Abstract: The present disclosure relates to a dual-function protein for regulating blood glucose and lipid metabolism, wherein said dual-function protein comprises a human GLP-1 analog and human FGF21. In the present disclosure, provided is a method for preparing said dual function protein, and also provided is the use of said dual-function protein in the preparation of a biological substance for treating type 2 diabetes, obesity, dyslipidemia, fatty liver disease and/or metabolic syndrome. The dual-function protein provided in the present disclosure can synergistically regulate blood glucose and lipid levels in vivo, and satisfy multiple requirements for patients with type 2 diabetes such as lowering blood glucose, relieving hepatic steatosis, reducing body weight and improving metabolic disorders of circulating lipids.

Abstract: One example method for ad hoc client audio device support for virtual conferences includes transmitting, via a first communication channel by a virtual conference device connected to a virtual conference hosted by a virtual conference provider, a first signal, the first signal including connection information to enable a network connection between a remote client device and the virtual conference device; receiving, by the virtual conference device via a second communication channel, a request to connect from the remote client device; connecting to the remote client device using the second communication channel; receiving, via the connection to the remote client device, an audio stream from the remote client device, the audio stream captured by a microphone of the remote client device; and providing the audio stream to the virtual conference.

Abstract: Implementations of the present disclosure relate to selecting a transmitting virtual access point (VAP) for a MBSSID set. A method comprises selecting a VAP from a set of VAPs as a transmitting VAP based on context information about the set of VAPs, at least one of the set of VAPs other than the transmitting VAP being determined as at least one non-transmitting VAP The method also comprises generating a beacon frame for the set of VAPs by including an identifier of the transmitting VAP in a header part of the beacon frame and including at least one identifier of the at least one non-transmitting VAP in a payload part of the beacon frame. A generated beacon frame is broadcasted. In this way, a transmitting VAP of a set of VAPs is no longer determined by default, but can be selected for different cases.

Abstract: Embodiments of the present disclosure relate to a computer-implemented method, device, and computer program product. The method includes: determining, based on a set of user behavior data over a first time period, a set of behavioral features for a user behavior over the first time period. The method further includes: determining, based on the set of behavioral features, a set of anomaly scores for the user behavior according to an anomaly detection model. The anomaly detection model is trained based on user behavior data over a second time period. The method further includes: updating a previously determined anomaly score threshold based on comparison of the determined set of anomaly scores with the anomaly score threshold. The anomaly score threshold is used for indicating whether the user behavior is anomalous. By continuously updating the anomaly score threshold, the solution uses the updated anomaly score threshold for anomaly detection of user behavior.

Abstract: A method in an illustrative embodiment includes determining that a first object authenticated by an electronic device is accessing the electronic device. The method further includes, in response to a second object being detected within a detection range using a radar of the electronic device, determining, based on a detected signal, that the second object is a person. The method further includes determining a distance and an angle between the second object and the electronic device based on an azimuth signal in the detected signal. The method further includes in response to determining that the distance is less than a distance threshold and the angle is less than an angle threshold, determining, based on the biological feature signal, whether the second object is trustworthy. The method further includes deauthenticating the first object in response to determining that the second object is untrustworthy.

Abstract: A vertical semiconductor structure with an integrated sampling structure and a method for manufacturing the same; the vertical semiconductor structure includes a vertical-semiconductor-structure unit cell, a sampling unit cell, a control electrode, a first electrode, a second electrode, and a sampling electrode. The sampling electrode performs real-time sampling of a voltage difference between the first electrode and the second electrode; a PN junction is formed between a first/second P-type diffusion region and a second N-type base region, which forms a potential barrier blocking electron emission from the sampling electrode. Therefore, a voltage signal of the sampling electrode is input into a protection circuit, which detects whether the vertical-semiconductor-structure unit cell is desaturated when it determines that the unit cell is in the open state. Second, a sampling resistor is connected between the sampling electrode and the first electrode to ensure the stable operation of the sampling unit cell.

Abstract: Embodiments are disclosed for a compensating circuit for a boost circuit that outputs a voltage that is a function of a voltage signal. In one or more examples, the compensation circuit may include a gain that is adjustable in proportion to voltage output of the boost circuit and inversely proportionate to input current to the boost circuit.

Abstract: In embodiments of the present disclosure, there is provided an approach for selecting a channel puncturing scheme based on channel qualities. A method comprises detecting channel interference between neighbor access points (APs), and determining whether a preamble puncturing needs to be enabled based on some puncturing conditions. After determining that a preamble puncturing needs to be enabled, scores for candidate puncturing patterns are calculated based on channel qualities of the sub-channels in the channel, and a proper puncturing pattern can be selected based on the respective scores. Embodiments of the present disclosure can help AP to achieve an effective and better puncturing scheme in real deployment.

Abstract: In embodiments of the present disclosure, there is provided an approach for aligning target beacon transmission time (TBTT) for multi-link connection. A method comprises setting up a first link and a second link between an access point (AP) and a wireless device based on multi-link operation (MLO), and obtaining a first TBTT of the first link and a second TBTT of the second link. The method further comprises aligning the first TBTT and the second TBTT at a start time, and then transmitting beacon frames on the first link and the second link according to the aligning of the first TBTT and second TBTT. Embodiments of the present disclosure synchronize and align the beacon TBTTs for different links, and can reduce the wake-up time on all active links, thereby saving power for the wireless device.

Abstract: Embodiments of the disclosure include a method, a device, and a computer program product for video processing. This method includes: selecting frames having features of a first type from a first instance of a video as a first candidate set, the first instance having a first resolution; generating a set of training frames based at least on the first candidate set; acquiring a set of corresponding frames for the set of training frames in a second instance of the video, the second instance having a second resolution lower than the first resolution; and determining, using the set of training frames and the set of corresponding frames, a conversion parameter for conversion from the second resolution to a third resolution. This solution provides a smaller-scale and higher-quality training set for the training of a video conversion model, thus improving the quality of training while saving computational resources and increasing training speed.

Abstract: The present invention relates to technical field of chemical synthesis of drugs, and provides a preparation method of Macitentan and intermediate compound thereof. Adding THF solution containing compound II and 5-bromo-2-chloropyrimidine slowly into THF solution containing base to react, or adding THF solution containing compound II and THF solution containing 5-bromo-2-chloropyrimidine slowly at the same time into THF solution containing base to react and obtain Macitentan (shown as compound I), wherein the base is selected from sodium hydride, potassium hydride, lithium hydride or lithium bis(trimethylsilyl)amide. The selectivity of the preparation method is very good, which is suitable for industrial production. The obtained product Macitentan has good quality and high yield. And the product compound II also has good quality and high yield, its HPLC purity is up to 99.0%, the content of impurity A is less than 0.20%, the content of impurity B is less than 0.25%.

Abstract: The present invention relates to technical field of chemical synthesis of drugs, and provides a preparation method of Macitentan and intermediate compound thereof. Adding THF solution containing compound II and 5-bromo-2-chloropyrimidine slowly into THF solution containing base to react, or adding THF solution containing compound II and THF solution containing 5-bromo-2-chloropyrimidine slowly at the same time into THF solution containing base to react and obtain Macitentan (shown as compound I), wherein the base is selected from sodium hydride, potassium hydride, lithium hydride or lithium bis(trimethylsilyl)amide. The selectivity of the preparation method is very good, which is suitable for industrial production. The obtained product Macitentan has good quality and high yield. And the product compound II also has good quality and high yield, its HPLC purity is up to 99.0%, the content of impurity A is less than 0.20%, the content of impurity B is less than 0.25%.

Abstract: The present invention relates to technical field of chemical synthesis of drugs, and provides a preparation method of Macitentan and intermediate compound thereof. Adding THF solution containing compound II and 5-bromo-2-chloropyrimidine slowly into THF solution containing base to react, or adding THF solution containing compound II and THF solution containing 5-bromo-2-chloropyrimidine slowly at the same time into THF solution containing base to react and obtain Macitentan (shown as compound I), wherein the base is selected from sodium hydride, potassium hydride, lithium hydride or lithium bis(trimethylsilyl)amide. The selectivity of the preparation method is very good, which is suitable for industrial production. The obtained product Macitentan has good quality and high yield. And the product compound II also has good quality and high yield, its HPLC purity is up to 99.0%, the content of impurity A is less than 0.20%, the content of impurity B is less than 0.25%.

Abstract: A coated granule, a solid dispersion, a composition, and a preparation for oral masking, which improve the taste masking effect of vortioxetine hydrobromide, and improve the patient adherence and compliance.

Abstract: A degassing chamber and a semiconductor processing apparatus are provided. The degassing chamber includes a chamber; a substrate container, movable within the chamber in a vertical direction; and a heating component, disposed within the chamber. A substrate transferring opening is formed through a sidewall of the chamber for transferring substrates into or out of the chamber. The heating component includes a first light source component and a second light source component. The chamber is divided into a first chamber and a second chamber by the substrate transferring opening. The first light source component is located in the first chamber, and the second light source component is located in the second chamber. The first light source component and the second light source component are provided for heating a substrate in the substrate container.

Abstract: The present invention relates to technical field of chemical synthesis of drugs, and provides a preparation method of Macitentan and intermediate compound thereof. Adding. THF solution containing compound II and 5-bromo-2-chloropyrimidine slowly into THF solution containing base to react, or adding THF solution containing compound II and THF solution containing 5-bromo-2-chloropyrimidine slowly at the same time into THF solution containing base to react and obtain Macitentan (shown as compound I), wherein the base is selected from sodium hydride, potassium hydride, lithium hydride or lithium bis(trimethylsilyl)amide. The selectivity of the preparation method is very good, which is suitable for industrial production. The obtained product Macitentan has good quality and high yield. And the product compound II also has good quality and high yield, its HPLC purity is up to 99.0%, the content of impurity A is less than 0.20%, the content of impurity B is less than 0.25%.

Abstract: An array substrate and a display panel are provided. The array substrate includes a base layer, a first metal layer, a first insulating layer, a second metal layer, a second insulating layer, a first electrode layer, and a reflective layer successively stacked along a direction perpendicular to a plane in which the base layer is located. The second metal layer is used to form a source and a drain of a thin film transistor. The first electrode layer is used to form a pixel electrode. The second insulating layer is provided with a through-hole. The pixel electrode is connected to the drain of the thin film transistor through the through-hole. The reflective layer is provided with a first through-hole, and an orthographic projection of the first through-hole onto the base layer covers an orthographic projection of the through-hole onto the base layer.

Abstract: For workflow test, a processor executes a workflow instance. The workflow instance includes a first workflow description of step names for a plurality of jobs. The processor further receives a modification to the first workflow description as the workflow instance executes. In addition, the processor synchronizes the modified workflow description to the executing workflow instance as the workflow instance executes. A workflow context of the executing workflow instance is preserved.

Abstract: The present invention is related to a replenishment method and device in an assembly line. A usage storage area for storing a first object set and a spare storage area for storing a second object set are defined in the replenishment apparatus. The replenishment apparatus comprises a fixing carrier in the usage storage area and a moving carrier in the spare storage area. The replenishment method comprises driving the moving carrier to move the second object set in the spare usage area to the fixing carrier in the usage storage area when a remaining number of objects in the first object set carried in the fixing carrier is zero and the first object set in the fixing carrier is removed; and moving the moving carrier to leave the fixing carrier and recover to the spare usage area.

Abstract: The present invention is related to a replenishment method and device in an assembly line. A usage storage area for storing a first object set and a spare storage area for storing a second object set are defined in the replenishment apparatus. The replenishment apparatus comprises a fixing carrier in the usage storage area and a moving carrier in the spare storage area. The replenishment method comprises driving the moving carrier to move the second object set in the spare usage area to the fixing carrier in the usage storage area when a remaining number of objects in the first object set carried in the fixing carrier is zero and the first object set in the fixing carrier is removed; and moving the moving carrier to leave the fixing carrier and recover to the spare usage area.