Abstract: A power supply (2000), a method of operating a power supply, a computer program (1020) and a computer program product (1010) is provided. The power supply is adapted to convert an oscillating Alternating Current, AC, to a single-directional Direct Current, DC. The power supply comprises a rectifier bridge (2100); a capacitor (2700); at least a first, a second and a third Electronic Switching Device, BSD (2400, 2500, 2600); a resistor (2300); a controller (2800) connected to the first, second and third ESDs. The controller is adapted to control switching of the first, second and third ESDs to operate the power supply in one of four modes of operation.

Abstract: An embedded terminals remote online development system is divided into three parts: an embedded terminal, a cloud forwarding platform and an IDE. Under remote online development, the cloud forwarding platform establishes a communication connection with the IDE through the Internet and establishes a connection with a communication module of the embedded terminal through a communication base station, so that the communication between the IDE and embedded terminal is completed. To be compatible with a local development mode, it is also possible to establish a connection between the IDE and the embedded terminal in a wired manner such as serial communication, to realize local online development. The embedded terminals remote online development system with good universality and flexibility is established in combination with a cloud platform, so the development difficulty of embedded terminals is lowered, repetitive work during development is reduced, development cycle is shortened, and development cost is reduced.

Abstract: Provided are a battery module and a battery pack. The battery pack includes a battery module. The battery module includes a liquid cooling structure and multiple battery cells. The liquid cooling structure includes an upper case plate, a lower case plate, and a support member. The upper case plate and the lower case plate are oppositely arranged to form accommodation spaces, a surface of the upper case plate and a surface of the lower case plate facing each other are cooling surfaces, the cooling surfaces are provided with grooves, and the grooves are adapted to the circumferential side surfaces of the battery cells. The support member extends along the upper case plate and is perpendicularly connected between the upper case plate and the lower case plate.

Abstract: Disclosed is a method for extracting near-field incident waves of a fixed offshore engineering structure. The method includes the steps: calculating a dimensionless wave height parameter and a dimensionless water depth parameter based on measured wave information, and selecting applicable wave theories; obtaining analytic signals of measured waves at one or two wave measuring points according to classification of the wave theories; calculating components occupied by incident waves in disturbance waves based on a first-order diffraction theory and a second-order diffraction theory respectively according to the classification; separating the wavelet signal analytic signals according to a proportion of the components of the incident waves for wavelet inverse transformation, to obtain the near-field incident waves of the fixed offshore engineering structure. The present invention can effectively take into account both computational efficiency and accuracy.

Abstract: An immunomodulatory hydrogel is prepared using methoxy polyethylene glycol amine (mPEG-NH2) as an initiator, the mPEG-NH2 reacts with L-tyrosine-N-carboxyanhydrides (L-Tyr-NCAs) to form a methoxy polyethylene glycol-poly L-tyrosine (PETyr) as a PETyr block copolymer. The PETyr is then reacted with tyrosinase to form an oxidized methoxy polyethylene glycol-poly L-tyrosine copolymer (PETO). By co-dissolving the PETO with octyl itaconate nanomicelles (ITA8) in a disperse medium, an itaconic acid-loaded immunomodulatory hydrogel (PETO-ITA8) is obtained.

Abstract: The present invention relates to the technical field of artificial intelligence, and in particular, to a road disease recognition method, system, a device, and a storage medium. The road disease recognition method includes: collecting a historical pavement image with a disease, and sequentially detecting and segmenting the historical pavement image to generate a plurality of visualized sample images, where the sample images have feature parameters marking the sample images; establishing a sample training set using the sample images; building a discriminative model for determining a disease category, and training the discriminative model using the sample training set to obtain a trained discriminative model; acquiring a new pavement image, sequentially detecting and segmenting the new pavement image, and then inputting the new pavement image that is detected and segmented into the discriminative model to generate a determination result.

Abstract: An extraction cleaner may include a base, an upright body pivotally coupled to the base, a supply tank removably coupled to the upright body and a recovery tank removably coupled to the upright body. The base may include a non-removable door and a removable suction nozzle. At least one fluid dispensing nozzle may be provided on the door. The door may be pivotally coupled to the base for providing access to an agitator. The cleaner may include and auto-spray configuration. The cleaner may include a support on the upright portion for the recovery tank. The cleaner may include an additive tank received in a receptacle of the supply tank. The recovery tank may include a float and/or an airflow management configuration. The cleaner may include a cleaning tool and a suction changeover valve and/or a fluid changeover valve. The cleaner may include a mixing valve for supplying fluid to a fluid changeover valve.

Abstract: The present disclosure relates to a GLP-1R agonist compound and use thereof, and specifically provides a compound represented by Formula I, or an isotope-labelled compound, a stereoisomer, or a pharmaceutically acceptable salt thereof, and use thereof as a medicament. The compound exhibits excellent agonistic effects and pharmacodynamic properties on GLP-1R and, as a modulator, is useful for manufacturing a medicament for the treatment, amelioration, or prevention of metabolic diseases and related diseases, thus having broad application prospects.

Abstract: Techniques are described for detecting a periphery of a surface based on a point set representing the surface. The surface may correspond to a display medium upon which content is projected. A shape model may be matched and aligned to a contour of the point set. A periphery or edge of the surface and corresponding display medium may be determined based on the aligned shape model.

Abstract: Provided herein are methods and compositions relating to glucagon-like peptide-1 receptor (GLP1R) libraries having nucleic acids encoding for a scaffold comprising a GLP1R binding domain. Libraries described herein include variegated libraries comprising nucleic acids each encoding for a predetermined variant of at least one predetermined reference nucleic acid sequence. Further described herein are protein libraries generated when the nucleic acid libraries are translated. Further described herein are cell libraries expressing variegated nucleic acid libraries described herein.

Abstract: The present application provides a display panel and a display device. The display panel includes pixel regions and light-transmitting regions, and the light-transmitting regions are located between adjacent pixel regions; the light-transmitting regions each include an adjustment sub-region; and the transmittance of a light adjustment layer in the adjustment sub-region to light of a preset color is greater than the transmittance of the light adjustment layer in regions in the light-transmitting region other than the adjustment sub-region to the light of the preset color. In this way, by increasing the transmittance to the light of the preset color in the adjustment sub-region in the light-transmitting region, the color of the light being transmitted through a screen may be closer to the preset color, which can meet the requirements for color of the display panel in application scenarios.

Abstract: A display panel, a method for manufacturing a display panel, and a display device. The display panel includes: a substrate; and a pixel definition layer located on the substrate. The pixel definition layer includes isolation structures and pixel openings; and a nucleation inhibiting layer including first inhibiting units. A first orthographic projection of each of the first inhibiting units on the pixel definition layer covers corresponding one of the pixel openings in the transitional display area; and common electrodes including a first common electrode and a second common electrode, a second orthographic projection of the first common electrode on the pixel definition layer covers the first display area and at least part of an area except for the first orthographic projections in the transitional display area.

Abstract: Embodiments of the disclosure provide an image data processing method and apparatus, an electronic device, and a storage medium. The method includes: obtaining, in response to an expression image trigger operation of a target user, an operation object associated with the expression image trigger operation on a session page of an instant messaging application; based on the operation object being image data, extracting a target object feature in the image data, and obtaining a first image set associated with the target object feature from an object feature library; and determining a target expression image in response to a selection trigger operation of the target user in the first image set, and displaying the target expression image on the session page.

Abstract: Provided herein are methods and compositions relating to variant nucleic acid libraries encoding for antibodies including single domain antibodies. Libraries generated using methods described herein have improved characteristics including improved binding affinity. Libraries described herein include variegated libraries comprising nucleic acids each encoding for a predetermined variant of at least one predetermined reference nucleic acid sequence. Further described herein are protein libraries generated when the nucleic acid libraries are translated. Further described herein are cell libraries expressing variegated nucleic acid libraries described herein.

Abstract: Provided herein are methods and compositions relating to adenosine A2A receptor libraries having nucleic acids encoding for a scaffold comprising an adenosine A2A binding domain. adenosine A2A receptor libraries described herein encode for immunoglobulins such as antibodies.

Abstract: A rolling bearing combined fault diagnosis method based on a multi-domain feature construction is provided, including: collecting vibration signals of rolling bearings, extracting time-domain and frequency-domain features of fault-sensitive vibration signals of the rolling bearings, and obtaining an in-domain feature set; performing an improved empirical mode decomposition on the vibration signals of the rolling bearings to obtain time-frequency features; constructing a multi-domain fault sample set based on the in-domain feature set and the time-frequency features; performing a fault mechanism analysis on the multi-domain fault sample set to obtain modulation features under each single fault; carrying out a feature engineering on the time-domain and frequency-domain features, and screening out relevant features, redundant features and irrelevant features; performing an unsupervised hierarchical clustering on test set fault samples, and then inputting the test set fault samples into a KNN model for a classifi

Abstract: A selective catalytic reduction (SCR) system, comprising a box body, a mixer, a baffle and a carrier, the mixer, the baffle and the carrier being sequentially arranged inside the box body in an airflow direction inside the box body, the baffle being provided with a plurality of through holes, and the distribution density of the through holes and/or the hole area of the through holes being negatively correlated with a distribution uniformity index of NH3 at the baffle. The configuration of the distribution density and the hole area of the through holes can improve the mixing uniformity of ammonia gas, so that a reaction effect of a catalyst and a mixed gas in the carrier is enhanced. The settings of the distribution density and the hole area of the through holes can improve the mixing uniformity of an ammonia gas.

Abstract: Provided herein are methods and compositions relating to CD3 libraries having nucleic acids encoding for a scaffold comprising a CD3 domain. CD3 libraries described herein encode for immunoglobulins such as antibodies.