Abstract: The present invention discloses a pyrimidine heterocyclic compound, and a preparation method and medical use thereof. Specifically, the present invention discloses a pyrimidine heterocyclic compound with a structure shown in Formula (A) or a pharmaceutically acceptable salt thereof (groups are each defined in the specification), a pharmaceutical composition comprising the compound, and use of the compound in treatment of cell proliferative diseases (such as cancers).

Abstract: A cryogenic full containment storage tank for realizing a low-liquid-level material extraction function by using a pump column, comprising an inner tank, an outer tank, a pump column, a submersible pump and a material pre-extraction device; wherein the material pre-extraction device comprises a cofferdam, a Venturi mixer, a backflow pipe, a return control valve, a lead-out pipeline and a liquid level detection system. The cryogenic full containment storage tank can make use of a low-temperature medium flowing back from the pump column to extract the low liquid level material outside the cofferdam into the cofferdam to form a local high liquid level and maintain the normal operation of the submersible pump.

Abstract: A configuration method for a mini program plug-in, includes: obtaining operation information of a plug-in setting operation performed by a mini program manager in a plug-in configuration page for a target mini program; determining plug-in configuration information for the target plug-in at the target mini program based on the operation information of the plug-in setting operation; obtaining a publishing instruction of the mini program manager for the target plug-in; generating a plug-in page access address for the target plug-in according to the plug-in configuration information in response to the publishing instruction; and sending the plug-in page access address for the target plug-in to a device of the mini program manager.

Abstract: Disclosed in the present invention is a compound as represented by formula (IA) or formula (IC) or a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof. The definition of each group in the formula is shown in the description for details. Further disclosed are a pharmaceutical composition containing the compound and the use thereof in the preparation of a drug for preventing and/or treating diseases or conditions related to HPK1 activity.

Abstract: A method comprises: determining that a vehicle is at a first location; controlling motion of the vehicle using an advanced driver assistance system (ADAS); determining a second location for the vehicle based on receiving a first sensor return indicating at least a first static object and a second static object; determining a third location for the vehicle based on a heading angle of the vehicle and a first travel distance of the vehicle since the first location; determining a fourth location for the vehicle by fusing the second and third locations with each other, and controlling the motion of the vehicle using the ADAS based on the fourth location.

Abstract: A method comprises: determining that a vehicle is at a first location; controlling motion of the vehicle using an advanced driver assistance system (ADAS); determining a second location for the vehicle based on receiving a first sensor return indicating at least a first static object and a second static object, and based on a first travel distance of the vehicle since the first location; determining a third location for the vehicle based on lane sensing information of a lane monitoring system of the vehicle and a second travel distance of the vehicle since the first location, the lane sensing information reflecting a vehicle curvature; determining a fourth location for the vehicle by fusing the second and third locations with each other; and controlling the motion of the vehicle using the ADAS based on the fourth location.

Abstract: A method comprises: determining that a vehicle is at a first location; controlling motion of the vehicle using an advanced driver assistance system (ADAS); determining a second location for the vehicle based on lane sensing information of a lane monitoring system of the vehicle and a first travel distance of the vehicle since the first location, the lane sensing information reflecting a lane curvature; determining a third location for the vehicle based on a heading angle of the vehicle and a second travel distance of the vehicle since the first location; determining a fourth location for the vehicle by fusing the second and third locations with each other; and controlling the motion of the vehicle using the ADAS based on the fourth location.

Abstract: A display panel is provided. The display panel includes a driving backplane with a connecting electrode, an insulating layer arranged on the connecting electrode, and a light-emitting unit arranged on the driving backplane. The insulating layer includes an opening exposing part of a surface of the connecting electrode. The light-emitting unit is electrically connected with a bump electrode, and the bump electrode is electrically connected with the connecting electrode through the opening. The opening has a ridge and furrow profile, which can increase an area of a sidewall of the opening, such that a contact area between the bump electrode and the sidewall is increased to prevent peeling or cracking between the films.

Abstract: A method of treating cancer in a subject by targeting at least one of KIF20A, SEPT7, RGS3 and EphrinB or disrupting protein-protein interaction in the EPHRINB-RGS3-KIF20A-SEPT7 axis. The method entails administering to the subject an RNA-based inhibitor such as an siRNA, shRNA, or miRNA or a peptide inhibitor which targets at least one of KIF20A, SEPT7, RGS3 and EphrinB or blocks the binding of KID20A to RGS3 and/or SEPT7 or the binding of EphrinB and RGS3.

Abstract: A flexible screen and a display device. The flexible screen includes a substrate, a cover plate and a display unit located between the substrate and the cover plate, where the flexible screen further includes a sealing layer and an insulating flow blocking medium, the sealing layer is located between the substrate and the cover plate, and surrounds a periphery of the display unit, a gap is formed between the sealing layer and the display unit, and the flow blocking medium fills the gap to isolate the display unit from outside.

Abstract: A computer-implemented method comprises: generating first output using a first sensor of a vehicle comprising an infrared camera or an event-based sensor, the first output indicating a portion of surroundings of the vehicle; providing the first output to a LiDAR of the vehicle having a field of view (FOV); configuring a resolution of the LiDAR based at least in part on the first output; generating a representation of at least part of the surroundings of the vehicle using the LiDAR; providing, to a perception component of the vehicle, second output of a second sensor of the vehicle and third output of the LiDAR, the perception component configured to perform object detection, sensor fusion, and object tracking regarding the second and third outputs, wherein the first output bypasses at least part of the perception component; and performing motion control of the vehicle using a fourth output of the perception component.

Abstract: A method of porting a first application, corresponding to a third-party development tool, into a second application, corresponding to a sub-application that depends on a parent application to run, is performed by an electronic device. The device transforms the first application from a first project mechanism into a second project mechanism. The device converts a design resource in the transformed first application from a first resource format into a second resource format. The device exports the design resource to a development tool of the sub-application. The device converts a code resource in the transformed first application from a first programming language into a second programming language. The device exports the code resource to the development tool of the sub-application, The device also performs secondary development on the design resource and the code resource in the development tool of the sub-application.

Abstract: Embodiments of the present disclosure discloses a display panel and a display device. The display panel includes a first substrate, a second substrate disposed opposite the first substrate, a plurality of electrical-connection units located between the first substrate and the second substrate, and a first barrier layer including at least a plurality of first barrier units located between the first substrate and the second substrate, wherein the electrical-connection units electrically connect the first substrate and the second substrate, and one of the first barrier units is disposed to surround one of the electrical-connection units.

Abstract: A compound having HPK1 inhibitory activity as shown in formula (IA) or (IC), and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, and a pharmaceutical composition containing the compound, and use of same in preparation of a drug for preventing and/or treating diseases or conditions associated with HPK1 activity.

Abstract: Disclosed are a pyrimidine-fused cyclic compound having an inhibitory effect on KRAS gene mutation, or a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, and a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating cancer.

Abstract: A method of porting a first application, corresponding to a third-party development tool, into a second application, corresponding to a sub-application that depends on a parent application to run, is performed by an electronic device. The device transforms the first application from a first project mechanism into a second project mechanism. The device converts a design resource in the transformed first application from a first resource format into a second resource format. The device exports the design resource to a development tool of the sub-application. The device converts a code resource in the transformed first application from a first programming language into a second programming language. The device exports the code resource to the development tool of the sub-application. The device also performs secondary development on the design resource and the code resource in the development tool of the sub-application.

Abstract: A pre-lithiated silicon-based anode includes a silicon-based anode, lithium disposed on a surface or in an interior of the silicon-based anode, and a protective coating on the surface of the silicon-based anode. The pre-lithiated silicon-based anode allows subsequent processing to be performed safely in the atmosphere.

Abstract: The present disclosure discloses a fracture repair device realizing transition from mechanical fixation (association of osteosynthesis, AO) to biological fixation (biological osteosynthesis, BO), including: a bone repair instrument, wherein auxiliary components are arranged at positions, close to a repaired bone surface, of the bone repair instrument, and each auxiliary component is made of a degradable metal material or a composite material thereof or a degradable polymeric material. The device of the present disclosure only has the advantages of AO rigid mechanical fixation, but also can effectively improve the defects of bone disconnection, fixed segment osteoporosis, re-fracture after defixation, etc., frequently occurring under AO rigid mechanical fixation, realizing transition from mechanical fixation (association of osteosynthesis, AO) to biological fixation (biological osteosynthesis, BO) during bone fixation or repair.

Abstract: A vehicle comprises: a vehicle body; a sub-short range active light sensor mounted to the vehicle body and configured to detect a lane boundary of a surface on which the vehicle is traveling; and an advanced driver-assistance system configured to register a lane boundary detection by the sub-short range active light sensor and perform an action in response to the lane boundary detection.

Abstract: A display panel is provided. The display panel includes a driving backplane with a connecting electrode, an insulating layer arranged on the connecting electrode, and a light-emitting unit arranged on the driving backplane. The insulating layer includes an opening exposing part of a surface of the connecting electrode. The light-emitting unit is electrically connected with a bump electrode, and the bump electrode is electrically connected with the connecting electrode through the opening. The opening has a ridge and furrow profile, which can increase an area of a sidewall of the opening, such that a contact area between the bump electrode and the sidewall is increased to prevent peeling or cracking between the films.