Patents by Inventor Qiang Tian

Qiang Tian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel compounds and compositions as protease inhibitors
    Publication number: 20030119788
    Abstract: The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.
    Type: Application
    Filed: September 9, 2002
    Publication date: June 26, 2003
    Applicant: AXYS PHARMACEUTICALS, INC.
    Inventors: Clifford M. Bryant, James T. Palmer, Robert M. Rydzewski, Eduardo L. Setti, Zong-Qiang Tian, Shankar Venkatraman, Dan-Xiong Wang
  • Benzoquinone ansamycins
    Publication number: 20030114450
    Abstract: The invention relates to benzoquinone ansamycin analogs useful for the treatment of cancer and other diseases or conditions characterized by undesired cellular proliferation or hyperproliferation. Therapies involving the administration of such benzoquinone ansamycin analogs, optionally in combination with an inhibitor of an HSP90 client protein, are useful to treat cancer and non-cancerous disease conditions.
    Type: Application
    Filed: August 5, 2002
    Publication date: June 19, 2003
    Inventors: Daniel Santi, David C. Myles, Zong-Qiang Tian, C. Richard Hutchinson, Robert Johnson, Yi-Qing Zhou, Li Feng
  • Novel compounds and compositions as protease inhibitors
    Publication number: 20030092634
    Abstract: The present invention relates to novel cysteine protease inhibitors; the pharmaceutically acceptable salts and N-oxides thereof; their uses as therapeutic agents and the methods of their making.
    Type: Application
    Filed: November 4, 2002
    Publication date: May 15, 2003
    Applicant: Axys Pharmaceuticals, Inc.
    Inventors: Ann M. Buysse, Rohan V. Mendonca, James T. Palmer, Zong-Qiang Tian, Shankar Venkatraman
  • Compounds and compositions as protease inhibitors
    Patent number: 6506733
    Abstract: Compounds of the formula: are provided, and are useful as cysteine protease inhibitors, particularly in the treatment of diseases such as osteoporosis or autoimmune disorders in which cathepsins K or S contribute to the pathology or symptomatolgy of the disease.
    Type: Grant
    Filed: March 15, 2000
    Date of Patent: January 14, 2003
    Assignee: Axys Pharmaceuticals, Inc.
    Inventors: Ann M. Buysse, Rohan V. Mendonca, James T. Palmer, Zong-Qiang Tian, Shankar Venkatraman
  • Compounds and compositions as protease inhibitors
    Patent number: 6476026
    Abstract: The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.
    Type: Grant
    Filed: March 15, 2000
    Date of Patent: November 5, 2002
    Assignee: Axys Pharmaceuticals, Inc.
    Inventors: Clifford M. Bryant, James T. Palmer, Robert M. Rydzewski, Eduardo L. Setti, Zong-Qiang Tian, Shankar Venkatraman, Dan-Xiong Wang
  • Gene whose expression promotes differentiation of myeloid progenitor cells into neutrophils and/or monocytes/macrophages
    Publication number: 20020108137
    Abstract: The present invention provides a human gene sequence that encodes the CDDP-1 polypeptide, which is involved in cell differentiation, in particular differentiation of undifferentiated progenitor cells into neutrophils, monocytes/macrophages, mast cells, and/or erythroid cells. Assays for detecting CDDP-1 expression, vectors that express CDDP-1, methods for using CDDP-1 to induce or promote cell differentiation, and transgenic animals deficient in one or both CDDP-1 alleles are described.
    Type: Application
    Filed: January 11, 2001
    Publication date: August 8, 2002
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Richard C. Schwartz, Qiang Tian
  • Motilide compounds
    Publication number: 20020094962
    Abstract: The present invention provides novel macrolide compounds of the formulas 1
    Type: Application
    Filed: November 21, 2001
    Publication date: July 18, 2002
    Inventors: Gary Ashley, Brian Metcalf, Zong-Qiang Tian, Daniel Santi
  • Novel compounds and compositions as protease inhibitors
    Publication number: 20020086996
    Abstract: The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.
    Type: Application
    Filed: December 14, 2001
    Publication date: July 4, 2002
    Applicant: AXYS PHARMACEUTICALS, INC.
    Inventors: Clifford M. Bryant, James T. Palmer, Robert M. Rydzewski, Eduardo L. Setti, Zong-Qiang Tian, Shankar Venkatraman, Dan-Xiong Wang