Abstract: Provided herein are bioactive molecule conjugates, preparation methods and use thereof, particularly bioactive molecule conjugates (such as antibody-drug conjugates and small molecule drug conjugates) obtained by improved coupling of a drug and a targeting moiety, as well as their preparation method and use for the treatment of a disease associated with an abnormal cell activity.

Abstract: The present invention relates to the field of garbage landfill. The present invention discloses a classified landfill device and method for garbage landfills, and the problem solved by the present invention is that the device proposed in the above background absorbs metals in the garbage using a magnet, but when the surface of the magnet has absorbed a large amount of metal, the device needs to be closed to treat the metal adsorbed on the surface of the magnet. The present invention comprises a screening mechanism, crushing mechanism and discharge mechanism. According to the classified landfill device and method for garbage landfill, the second crushing knife is set at an angle to divert the falling garbage to the front and rear sides, so that the two first crushing knives and the second crushing knife cooperate to crush the garbage respectively to avoid excessive accumulation of garbage.

Abstract: A temperature fuse assembly for a high-power DC circuit is provided. The temperature fuse assembly includes a case extending from a first case end to a second case end and an isolated lead projecting from the second case end. A bushing electrically isolates the isolated lead from the case. A high-gauge wire is electrically connected to the case at a first wire end and electrically connected to the isolated lead at a second wire end. A portion of the high-gauge wire is helically wound about an exterior of the bushing. When a temperature of the temperature fuse assembly exceeds a threshold temperature, the temperature fuse assembly is configured to conduct a DC current of the high-power DC circuit through the high-gauge wire. The high-gauge wire is configured to melt under a load of the DC current and interrupt the high-power DC circuit.

Abstract: A plural material dispensing system (10) includes a pump (38) having a cylinder (52) mounted between a first bracket (32) and a second bracket (34), a piston (54) disposed within the cylinder (52), and a pump rod (48) extending from the piston (54) and out of the first bracket (32). Material is provided to the cylinder (52) through a flow path extending through the pump rod (48). The piston (54) drives material downstream out of the cylinder (52), and the interface between the piston (54) and the inner surface of the cylinder (52) provides a dynamic seal during pumping. The flow of material into and out of the pump (38) is controlled by actively-controlled inlet and outlet valves.

Abstract: Disclosed is an implementation method for ultrasensitive Brink control for a delayed enzymatic reaction based on DNA strand displacement (DSD), relating to the field of feedback control technology based on DSD in biological systems. The method includes obtaining an enzymatic reaction process model with time delay; constructing a CRN-based Brink controller; obtaining a static mapping expression between an output of the Brink controller and an output of the system under a steady state condition; constructing a Brink controller by DSD reaction; obtaining a time delay representation, and applying it to DNA implementations of the enzymatic reaction process model; and combined with the Brink controller, controlling a delayed enzymatic reaction process model. The present invention is structurally free of subtraction, reduces the number of abstract chemical reactions required to implement, and greatly simplifies DNA implementation.

Abstract: A circuit board, a display panel and a display apparatus are provided. The circuit board includes a main circuit board and an adapter circuit board stacked on the main circuit board. The adapter circuit board is provided with at least one first pad region, and the first pad region includes a hollowed region penetrating through the adapter circuit board and multiple first pads distributed around the hollowed region. The main circuit board is provided with at least one second pad region including multiple second pads, and the first pads of each of the first pad regions are respectively soldered to the multiple second pads of a corresponding second pad region.

Abstract: Provided is a reverse-conducting IGBT chip including a first conductive type substrate; and several first conductive type short circuit regions arranged at intervals below the substrate and adjacent to a collector region. The short circuit regions are located outside a first preset range having the center of a chip as a center, in a second preset range outside the first preset range and having the center of the chip as a center, in a third preset range outside the second preset range and having the center of the chip as a center, and in a range outside the third preset range and enclosed by a chip edge.

Abstract: A drinking straw is integrally formed of a food-grade plastic material, is flexible and comprises a sheet body, a first engaging portion, and a second engaging portion. The first engaging portion and the second engaging portion are respectively formed on two side edges of the sheet body, and the sheet body can be wound into a tubular shape to enable the first engaging portion to engage with the second engaging portion to form a suction channel in the drinking straw. Consumers can clean an inner part of the drinking straw by disengaging the first engaging portion and the second engaging portion. The drinking straw of the present invention can be cleaned easily, can reduce the cost of manufacture, and can improve suction efficiency.

Abstract: A speech noise reduction processing method, an apparatus, a computer device and a storage medium. The method comprises: responsive to a distance between a speech collection device and a target object being detected to reach a preset value, acquiring a noisy speech signal collected by the speech collection device and performing frequency division processing on the noisy speech signal to obtain a low-frequency band signal; acquiring an amplitude spectrum and a phase spectrum of the low-frequency band signal; acquiring a modulation domain signal corresponding to the amplitude spectrum; performing spectral subtraction to obtain a noise-reduced modulation domain amplitude spectrum; compensating the modulation domain phase spectrum to obtain the compensated modulation domain phase spectrum; and obtaining a noise-reduced low-frequency band signal based on the compensated modulation domain phase spectrum, the noise-reduced modulation domain amplitude spectrum and the phase spectrum of the low-frequency band signal.

Abstract: In an example, a particular type of deep learning model is used in the global model of the GDMix model: a Factorization Machine. A Factorization Machine combines a Support Vector Machine (SVM) and Matrix Factorizations. It has the advantage of modeling data with huge sparsity well, while maintaining a linear time complexity. A modification may be further made to the Factorization Machine by introducing L2 norm reduction. This acts to divide calculations made by the Factorization Machine into a portion that can be precomputed and a portion that cannot be precomputed. The portion that can be precomputed is then precomputed in an offline manner. As such, when the model is operated in an online manner, the Factorization Machine only needs to compute the portion that cannot be precomputed, reducing the number of operations that need to performed at runtime and greatly improving processing speed over prior machine learned models.

Abstract: A faucet that includes a housing with a water supply assembly, a soap supply assembly, first and second sensing probe assemblies, and a controller provided in the housing, wherein a sensing region of the first sensing probe assembly is an upper portion of the housing, a sensing region of the second sensing probe assembly is a lower portion of the housing, an output terminal of each sensing probe assembly is electrically connected with an input terminal of the controller, and an output terminal of the controller is electrically connected with a control terminal of each of the water and soap supply assemblies. The controller controls the water supply assembly to start/stop water supply according to the sensing signal from the first or second sensing probe assembly, and controls the soap supply assembly to start/stop soap supply according to the sensing signal from the first or second sensing probe assembly.

Abstract: Computer-implemented machine learning-based techniques for assisted electronic message composition in a vertical messaging context. The vertical messaging context may be any electronic messaging context in which senders repetitively compose electronic messages to send to recipients where the messages are not identical but nonetheless have common tone, sentiment, content, and structure. The techniques assist users that compose electronic messages in a particular vertical messaging context in composing those messages quickly, with few or no grammatical errors, and with a likelihood of being positively received by the recipients of the messages.

Abstract: Provided are a method for manufacturing a molded composite inductor, and a molded composite inductor. The method includes: putting a plurality of conductors apart from each other into a mold, and extending two ends of each of the plurality of conductors out of the mold; filling the mold with magnetic powder such that the magnetic powder covers the plurality of conductors, and applying pressure to the magnetic powder such that the magnetic powder forms a magnetic body and is integrated with the plurality of conductors to form an inductor module.

Abstract: The present application relates to an internally embedded copper plate-type soft magnetic powder core inductor, a preparation method therefor, and a use thereof. The internally embedded copper plate-type soft magnetic powder core inductor comprises a copper plate, a surface of the copper plate is covered with a soft magnetic material, and an interfacing area of the soft magnetic material and the copper plate includes an insulating resin material.

Abstract: A faucet that includes a housing with a water supply assembly, a soap supply assembly, first and second sensing probe assemblies, and a controller provided in the housing, wherein a sensing region of the first sensing probe assembly is an upper portion of the housing, a sensing region of the second sensing probe assembly is a lower portion of the housing, an output terminal of each sensing probe assembly is electrically connected with an input terminal of the controller, and an output terminal of the controller is electrically connected with a control terminal of each of the water and soap supply assemblies. The controller controls the water supply assembly to start/stop water supply according to the sensing signal from the first or second sensing probe assembly, and controls the soap supply assembly to start/stop soap supply according to the sensing signal from the first or second sensing probe assembly.

Abstract: The invention is a novel lower-trolley system, comprising a lower trolley (3), a lower-trolley hoisting system, and a lower-trolley travelling system. The lower trolley (3), the lower-trolley hoisting system and the lower-trolley travelling system are all arranged on a quay crane; the lower-trolley hoisting system drives a hoist (14) of the lower trolley (3) to rise and fall, and the lower-trolley travelling system pulls the lower trolley (3) to make same travel in the direction of a double-trapezoid four-track girder (1) of the quay crane; and the lower trolley (3) is hung upside down on outer-side tracks (15) of the double-trapezoid four-track girder (1), and a container (12) hoisted by an upper trolley (2) can pass through the lower trolley (3).

Abstract: An upgraded quay crane system and an operation process, wherein a conventional quay crane girder is upgraded into a double-trapezoid four-track girder (1). An upper trolley (2) travels on upper trolley running tracks (a16) on an inner side of the double-trapezoid four-track girder (1), a lower trolley (3) is suspended upside down on lower trolley running tracks (a8) on an outer side of the double-trapezoid four-track girder (1), and a container (5) hoisted by the upper trolley (2) via a hoist (4) is able to pass through the lower trolley (3). The present quay crane system improves on the conventional quay crane having a single operation trolley by adding one more operation trolley on the outer side of the original quay crane girder. The two trolleys are vertically disposed, and the space structure for the lower trolley is cleverly designed, such that the two trolleys can operate independently without interfering with each other.