Abstract: A composition and a use of the composition in the preparation of a medicament for treating eye diseases. The composition includes 0.5-1.5% by weight of a muscarinic acetylcholine receptor M3 agonist; 0.005-0.5% by weight of naphazoline, a pharmaceutically acceptable salt thereof or a combination thereof; and 0.1-1% by weight of ketorolac tromethamine. While enhancing the effect of a muscarinic acetylcholine receptor M3 agonist such as a pilocarpine active ingredient in treating presbyopia, the composition effectively significantly reduces or even eliminates side effects caused by the pilocarpine active ingredient.

Abstract: A method and device for optimal power flow calculation in power systems based on generalized Nash equilibrium are disclosed.

Abstract: A camera is provided. The camera includes an optical assembly having one or more lens defining an optical axis. The camera also includes an image sensor and an enclosure forming an exterior wall of the camera. The camera further includes an actuator assembly to move the image sensor relative to the optical assembly. In addition, the camera includes a base that is a static component of the camera, wherein the base comprises a seat that faces in a direction that is parallel to the optical axis and away from the optical assembly. The camera also includes a flexure that is attached to the seat, that suspends the image sensor from the base, and that allows motion of the image sensor enabled by the actuator assembly. In some cases, the base does not extend between the flexure and the enclosure.

Abstract: A method and a system for optimizing operating swing of a vertical shaft suspended hydrogenerator unit, and the method includes: measure turning swing and operating parameters of the unit during turning, calculate direction of relative displacement between the rotating center of each bearing for the unit and a center line of a main shaft, and calculate and adjust offset distance of an installation center for a guide bearing to a certain direction by the temperature of a bearing bush; then carry out a temperature rise test of the unit, optimize the operating swing of the hydrogenerator unit while the bush temperature is less than the design requirement, and select optimal bush gap to achieve optimal operating swing and ensure that the bush temperature, the cooling oil level, the cooling oil temperature and the operating swing reach the most scientific and reasonable balanced state.

Abstract: A camera may comprise a sensor-shift structure including a substrate to allow an image sensor to be movable relative to one or more lenses of the camera in one or more directions. During a drop or shock event, the substrate may experience unwanted movement and collide with a base structure in the vicinity. The camera may include one or more protection structures to prevent the substrate from directly colliding with the base structure to protect the base structure from potential damages. The protection structures may be implemented using components placed at the substrate and/or the base structure.

Abstract: The present invention provides a method for synthesizing tyloxapol of formula (I), including the following steps: first reacting p-tert-octylphenol of formula (III) with formaldehyde under alkaline conditions to obtain 2,5-dimethylol p-tert-octylphenol of formula (IV); then reacting 2,5-dimethylol p-tert-octylphenol with p-tert-octylphenol of formula (III) under acidic conditions to obtain the phenolic resin of formula (II); and finally, reacting the phenolic resin of formula (II) with ethylene oxide to obtain tyloxapol of formula (I).

Abstract: The present invention relates to the synthesis of 3-[(1S,2S)-1-[5-[(4S)-2,2-dimethyloxan-4-yl]-2-[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-4-methyl-6,7-dihydro-4H-pyrazolo [4,3-c] pyridine-5-carbonyl] indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one, or a salt thereof, and related synthetic intermediate compounds.

Abstract: In one embodiment, a method for achieving zero packet loss in wireless roaming is implemented by a processor of a wireless client device in a system. The wireless client device establishes a first data plane in association with a first radio connected to a first access point and a second data plane in association with a second radio. The first data plane is different from and operates concurrently with the second data plane. The wireless client device determines a second access point by scanning a plurality of operating channels using the second radio. The wireless client device synchronizes the second data plane with a network controller to connect the second radio with the second data plane to the second access point. The wireless client device switches traffic of the first data plane connected to the first access point to the second data plane connected to the second access point.

Abstract: Provided is a method for preparing oxidized glutathione and a new crystal form and impurity thereof, including the following steps: using dimethyl sulfoxide (DMSO) as an oxidizing agent to oxidize reduced glutathione to crude oxidized glutathione; and recrystallizing and refining in purified water to obtain high-purity heptahydrate crystals of oxidized glutathione.

Abstract: A flexure for a camera module is provided. The flexure includes a dynamic platform to which an image sensor is connected such that the image sensor moves with the dynamic platform. The flexure also includes a static platform connected to a static portion of the camera. The flexure further includes a plurality of flexure arms that mechanically connect the dynamic platform to the static platform. The plurality of flexure arms includes a first flexure arm including one or more signal traces having a first impedance and a base layer having a first width. The plurality of flexure arms includes a second flexure arm including one or more signal traces having a second impedance and a base layer having a second width. The first impedance is greater than the second impedance. The first width is less than the second width. The second flexure arm routes image data from the image sensor.

Abstract: The invention belongs to the field of drug preparations and discloses an ophthalmic sustained-release drug delivery system. The ophthalmic sustained-release drug delivery system consists of biocompatible solid and liquid substances, as well as substances with pharmacological activity and pharmacologically acceptable salt of the substances, and can be mixed with a matrix which is liquid at room temperature, has the density larger than that of water and almost incompatible with water, so that the drug release rate and the degradation time of the delivery system are changed. According to the sustained-release drug delivery system, a drug is solidified into a ball at an eye, so that the drug liquidity is reduced, drug release is sustained, the administration times is reduced, and the compliance of patients is improved.

Abstract: A method comprises steps of in response to an initiating signal, providing a drive signal with a first amplitude range for a first period to drive an transducer of the ultrasonic surgical instrument; subsequent to the first period, providing a first transition signal with a decreasing amplitude for a first predetermined interval; subsequent to the first predetermined interval, providing a drive signal with a second amplitude range for a second period, wherein an upper limit of the second amplitude range is lower than a lower limit of the first amplitude range; subsequent to the second period, providing a second transition signal with an increasing amplitude for a second predetermined interval; and subsequent to the second predetermined interval, providing a drive signal with a third amplitude range for a third period, wherein a lower limit of the third amplitude range is higher than the upper limit of the second amplitude range.

Abstract: The invention belongs to the field of drug preparations and discloses an ophthalmic sustained-release drug delivery system. The ophthalmic sustained-release drug delivery system consists of biocompatible solid and liquid substances, as well as substances with pharmacological activity and pharmacologically acceptable salt of the substances, and can be mixed with a matrix which is liquid at room temperature, has the density larger than that of water and almost incompatible with water, so that the drug release rate and the degradation time of the delivery system are changed. According to the sustained-release drug delivery system, a drug is solidified into a ball at an eye, so that the drug liquidity is reduced, drug release is sustained, the administration times is reduced, and the compliance of patients is improved.

Abstract: A basket and a stroller with the basket are disclosed. The stroller includes a frame, a seat and a basket. The seat is disposed on the frame, and the basket is connected to the frame and located under the seat. The basket includes a bottom, a front stopper, a rear stopper and two side stoppers. The front stopper, the rear stopper and the side stoppers are connected to a front side, a rear side, and left and right sides of the bottom respectively. By the movement of the rear stopper with respect to the bottom, the deformation of the rear stopper itself, or the detachable connection of the rear stopper to the bottom, an opening for objects to enter the basket is formed at a rear side of the basket.

Abstract: Various embodiments include an engaging arrangement that may be used to attach a lens barrel to a lens carrier of a camera. In some embodiments, the engaging arrangement may restrict movement of the lens barrel relative to the lens carrier along at least an optical axis. In various examples, the engaging arrangement may include one or more grooves and one or more protrusions. For instance, a groove may be defined by the lens barrel or the lens carrier, and a protrusion may extend from the lens barrel or the lens carrier to at least partially into the groove. In some cases, the engaging arrangement may include an adhesive positioned continuously 360 degrees around the engaging arrangement between the lens barrel and the lens carrier.

Abstract: The present invention belongs to the field of medicine and relates to a method for preparing pranoprofen. The present invention also relates to a composition containing pranoprofen and impurities, a quality control method, an intermediate compound for synthesizing pranoprofen and a preparation method thereof. The method of the present invention overcomes the deficiencies of the prior art, shortens the synthetic route, lowers the requirements of process conditions, simplifies the process operation, improves labor safety, is more suitable for industrial production, is more environmentally friendly and has higher yield.

Abstract: A high-pressure composite container is provided. At least a plastic-liner is provided with a plastic shell and a metal end encapsulated by the plastic shell. The plastic-liner of the sealing structure only consists of the plastic shell and the metal end, and the sealing structure is simple. The metal end and a bottle mouth valve jointly compress a sealing ring on the bottle mouth valve, so that the sealing ring forms a stable compression amount, and finally the high-pressure gas cylinder has excellent sealing performance. In addition, the metal end and the plastic shell are well positioned both axially and circumferentially. In the case of high and low pressure and temperature alternation, the relative positions of the metal end and the plastic shell do not change, and a sealing surface of the plastic shell does not deform and dislocate.

Abstract: In some embodiments, a camera actuator includes an actuator base, an autofocus voice coil motor, and an optical image stabilization voice coil motor. In some embodiments, the autofocus voice coil motor includes a lens carrier mounting attachment moveably mounted to the actuator base, a plurality of shared magnets mounted to the base, and an autofocus coil fixedly mounted to the lens carrier mounting attachment for producing forces for moving a lens carrier in a direction of an optical axis of one or more lenses of the lens carrier. In some embodiments, the optical image stabilization voice coil motor includes an image sensor carrier moveably mounted to the actuator base, and optical image stabilization coils moveably mounted to the image sensor carrier within the magnetic fields of the shared magnets, for producing forces for moving the image sensor carrier in a plurality of directions orthogonal to the optical axis.

Abstract: A flexure for a camera includes a dynamic platform to which an image sensor and a substrate are connected such that the image sensor and the substrate move together with the dynamic platform. A driver associated with an actuator to move the image sensor relative to a lens group is mounted to the substrate. The flexure also includes a static platform connected to a static portion of the camera, a plurality of flexure arms that mechanically connect the dynamic platform to the static platform, a routing layer and a base layer both at least partially forming the dynamic platform, the static platform, and the plurality of flexure arms, and at least one segmentation region extending through the base layer and configured to physically isolate a return current from the driver and through the base layer from a return current from the image sensor and through the base layer.

Abstract: An ultrasonic surgical instrument includes a waveguide for transmitting ultrasonic energy, the distal end of the waveguide connected to a blade; a jaw member pivotable with respect to the blade; an inner tube sleeved on the waveguide; and an outer tube sleeved on the inner tube. The jaw member is pivotally connected to the distal end of the outer tube, the distal end of the inner tube acting on the jaw member, and the inner tube sliding with respect to the outer tube and driving the jaw member to pivot with respect to the blade. A first abutting portion provided on the distal ends of the inner tube and the outer tube forms a support between the inner and outer tube, so as to avoid a radial clearance change between the inner tube and the outer tubes without affecting the relative sliding movement of the inner and outer tubes.