Patents by Inventor Qiangwei FAN

Qiangwei FAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multi-target compound with anticoagulation and antiplatelet activity, preparation method therefor, and use thereof
    Patent number: 11643439
    Abstract: Provided is a multi-target compound with anticoagulation and platelet GPIIb/IIIa receptor antagonism. The formula of the multi-target compound is as follows: A-L-B-L?-C. A and B are binding sites with a thrombin, C is a binding site with a platelet GPIIb/IIIa receptor, L is a first linking group, and L? is a second linking group. Also provided are a preparation method for the compound and use of the compound. The compound has the effects on inhibiting human thrombin activity and a platelet GPIIb/IIIa receptor in vitro, and has the effects on antiplatelet aggregation in vitro/in vivo, and anticoagulation and antithrombosis in vivo.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: May 9, 2023
    Assignee: SHAANXI MICOT TECHNOLOGY LIMITED COMPANY
    Inventors: Wei Ding, Qiangwei Fan, Bo Yin, Guoqin Fu
  • MULTI-TARGET COMPOUND WITH ANTICOAGULATION AND ANTIPLATELET ACTIVITY, PREPARATION METHOD THEREFOR, AND USE THEREOF
    Publication number: 20180305409
    Abstract: Provided is a multi-target compound with anticoagulation and platelet GPIIb/IIIa receptor antagonism. The formula of the multi-target compound is as follows: A-L-B-L?-C. A and B are binding sites with a thrombin, C is a binding site with a platelet GPIIb/IIIa receptor, L is a first linking group, and U is a second linking group. Also provided are a preparation method for the compound and use of the compound. The compound has the effects on inhibiting human thrombin activity and a platelet GPIIb/IIIa receptor in vitro, and has the effects on antiplatelet aggregation in vitro/in vivo, and anticoagulation and antithrombosis in vivo.
    Type: Application
    Filed: August 5, 2015
    Publication date: October 25, 2018
    Inventors: Wei DING, Qiangwei FAN, Bo YIN, Guoqin FU