Patents by Inventor QIANHUI YI

QIANHUI YI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted imidazoles for the treatment of cancer
    Patent number: 11434231
    Abstract: There are provided compounds, their preparation and their use in the treatment of KRAS-driven cancers. The compounds according to the invention (general formula Class III) disrupt dimerization of KRAS and are inhibitors of KRAS mutants such as KRAS G12D, KRAS G12V and KRAS 12C. Embodiments of the compounds according to the invention are selective inhibitors of KRAS mutants over the wild-type (WT) KRAS.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: September 6, 2022
    Inventors: Xiaohong Tian, Jian Hui Wu, Qianhui Yi
  • Substituted oxazoles for the treatment of cancer
    Patent number: 10844051
    Abstract: There are provided compounds, their preparation and their use in the treatment of medical conditions including cancers and immune disorders.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: November 24, 2020
    Inventors: Jian Hui Wu, Xiaohong Tian, Qianhui Yi
  • COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCERS AND OTHER MEDICAL CONDITIONS
    Publication number: 20200339554
    Abstract: There are provided compounds, their preparation and their use in the treatment of KRAS-driven cancers. The compounds according to the invention (general formula Class III) disrupt dimerization of KRAS and are inhibitors of KRAS mutants such as KRAS G12D, KRAS G12V and KRAS 12C. Embodiments of the compounds according to the invention are selective inhibitors of KRAS mutants over the wild-type (WT) KRAS.
    Type: Application
    Filed: July 8, 2020
    Publication date: October 29, 2020
    Inventors: XIAOHONG TIAN, JIAN HUI WU, QIANHUI YI
  • COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCERS AND OTHER MEDICAL CONDITIONS
    Publication number: 20180208586
    Abstract: There are provided compounds, their preparation and their use in the treatment of medical conditions including cancers and immune disorders.
    Type: Application
    Filed: July 22, 2016
    Publication date: July 26, 2018
    Inventors: JIAN HUI WU, XIAOHONG TIAN, QIANHUI YI