Abstract: The present disclosure provides a packaging apparatus. The packaging apparatus may include a main body. The main body may include a base plate, a first side plate, and a second side plate. The first side plate and the second side plate may be distributed around the base plate. The packaging apparatus may include an elastic sheet disposed above the base plate. The elastic sheet may include a first fixing part and a second fixing part. The first fixing part and the second fixing part may be connected with the first side plate and the second side plate, respectively. A space may be configured between the base plate and the elastic sheet. When the packaging apparatus is used to package a subject, the first side plate and the second side plate may be folded away from a side of the base plate where the subject is located.

Abstract: The present invention belongs to the field of pharmaceutical manufacturing technology. The present invention provides a pharmaceutical composition of a conjugate and a preparation method thereof. The pharmaceutical composition is preferably administered by injection. The docetaxel conjugate has a structural formula as shown in the following formula: (I).

Abstract: The present disclosure provides a packaging apparatus. The packaging structure may include a main body including one or more base plates and one or more elastic sheets. Each of the base plates may have two opposite first side edges, two opposite second side edges, and an opening. Each of the one or more elastic sheets may correspond to one of the one or more base plates. The one or more elastic sheets may be physically connected with the main body, and each of the one or more elastic sheets may cover at least a part of the opening. The main body may further include a first side plate disposed beside at least one of the two opposite first side edges and a second side plate disposed beside each of the two opposite second side edges.

Abstract: A method for managing data asset in a data bank is provided, including: acquiring a confirmation authentication request, wherein the confirmation authentication request includes a data asset to be confirmed, characteristic information of the data asset and characteristic information of a data provider uploaded by the data provider; performing a confirmation verification on the data asset through a confirmation blockchain based on the data asset, the characteristic information of the data asset and the characteristic information of the data provider in response to the confirmation authentication request; storing confirmation information corresponding to the data asset into the confirmation blockchain after it is determined that the data asset has passed the confirmation verification; inserting identification data for tracing a data owner into the data asset, obtaining and storing the data asset having the identification data.

Abstract: A method, an apparatus, and a system for time synchronization based on in-band telemetry are disclosed. The method includes: acquiring an estimated value of delay in a first transmission direction and an estimated value of delay in a second transmission direction; wherein the estimated value of delay in the first transmission direction is determined according to multiple delay samples in the first transmission direction, and the estimated value of delay in the second transmission direction is determined according to multiple delay samples in the second transmission direction, the first transmission direction is a direction from a second device to a first device, and the second transmission direction is vice versa; and determining a time system error of the first device relative to the second device according to the estimated value of delay in the first transmission direction and the estimated value of delay in the second transmission direction.

Abstract: The present disclosure provides a packaging apparatus. The packaging apparatus may include a main body. The main body may include a base plate, a first side plate, and a second side plate. The first side plate and the second side plate may be distributed around the base plate. The packaging apparatus may include an elastic sheet disposed above the base plate. The elastic sheet may include a first fixing part and a second fixing part. The first fixing part and the second fixing part may be connected with the first side plate and the second side plate, respectively. A space may be configured between the base plate and the elastic sheet. When the packaging apparatus is used to package a subject, the first side plate and the second side plate may be folded away from a side of the base plate where the subject is located.

Abstract: The present disclosure provides a packaging apparatus. The packaging structure may include a main body including one or more base plates and one or more elastic sheets. Each of the base plates may have two opposite first side edges, two opposite second side edges, and an opening. Each of the one or more elastic sheets may correspond to one of the one or more base plates. The one or more elastic sheets may be physically connected with the main body, and each of the one or more elastic sheets may cover at least a part of the opening. The main body may further include a first side plate disposed beside at least one of the two opposite first side edges and a second side plate disposed beside each of the two opposite second side edges.

Abstract: A method, an apparatus, and a system for time synchronization based on in-band telemetry are disclosed. The method includes: acquiring an estimated value of delay in a first transmission direction and an estimated value of delay in a second transmission direction; wherein the estimated value of delay in the first transmission direction is determined according to multiple delay samples in the first transmission direction, and the estimated value of delay in the second transmission direction is determined according to multiple delay samples in the second transmission direction, the first transmission direction is a direction from a second device to a first device, and the second transmission direction is vice versa; and determining a time system error of the first device relative to the second device according to the estimated value of delay in the first transmission direction and the estimated value of delay in the second transmission direction.

Abstract: A method for managing data asset in a data bank is provided, including: acquiring a confirmation authentication request, wherein the confirmation authentication request includes a data asset to be confirmed, characteristic information of the data asset and characteristic information of a data provider uploaded by the data provider; performing a confirmation verification on the data asset through a confirmation blockchain based on the data asset, the characteristic information of the data asset and the characteristic information of the data provider in response to the confirmation authentication request; storing confirmation information corresponding to the data asset into the confirmation blockchain after it is determined that the data asset has passed the confirmation verification; inserting identification data for tracing a data owner into the data asset, obtaining and storing the data asset having the identification data.

Abstract: The present disclosure discloses a method and a device for accessing location related information. The method includes: receiving a request for assigning a network address to a POI; encoding the POI based on a preset geographical name code database to obtain a POI code of the POI; mapping the POI code into a network address, the network address comprising at least one of an IPv6 unicast address, an IPv6 multicast address, or a domain name; and sending the network address to a network device, enabling the network device to obtain location related information of the POI by accessing a site corresponding to the network address.

Abstract: The present disclosure discloses a method and a device for accessing location related information. The method includes: receiving a request for assigning a network address to a POI; encoding the POI based on a preset geographical name code database to obtain a POI code of the POI; mapping the POI code into a network address, the network address comprising at least one of an IPv6 unicast address, an IPv6 multicast address, or a domain name; and sending the network address to a network device, enabling the network device to obtain location related information of the POI by accessing a site corresponding to the network address.

Abstract: The present invention belongs to the field of pharmaceutical manufacturing technology. The present invention provides a pharmaceutical composition of a conjugate and a preparation method thereof. The pharmaceutical composition is preferably administered by injection. The docetaxel conjugate has a structural formula as shown in the following formula: (I).

Abstract: The present invention discloses a codon-optimized gene encoding major capsid protein L1 of human papilloma virus, which is capable, after transduced into a yeast cell, of efficiently expressing the major capsid protein L1 of human papilloma virus. The present invention also discloses an immunogenic macromolecule which is essentially produced by expression of said codon-optimized gene encoding the major capsid protein L1 of human papilloma virus in a yeast cell. The present invention further discloses the use of said immunogenic macromolecule and a composition comprising said immunogenic macromolecule.

Abstract: The present invention discloses a codon-optimized gene encoding major capsid protein L1 of human papilloma virus, which is capable, after transduced into a yeast cell, of efficiently expressing the major capsid protein L1 of human papilloma virus. The present invention also discloses an immunogenic macromolecule which is essentially produced by expression of said codon-optimized gene encoding the major capsid protein L1 of human papilloma virus in a yeast cell. The present invention further discloses the use of said immunogenic macromolecule and a composition comprising said immunogenic macromolecule.

Abstract: The present invention discloses a codon-optimized gene encoding major capsid protein L1 of human papilloma virus, which is capable, after transduced into a yeast cell, of efficiently expressing the major capsid protein L1 of human papilloma virus. The present invention also discloses an immunogenic macromolecule which is essentially produced by expression of said codon-optimized gene encoding the major capsid protein L1 of human papilloma virus in a yeast cell. The present invention further discloses the use of said immunogenic macromolecule and a composition comprising said immunogenic macromolecule.

Abstract: The present invention discloses a codon-optimized gene encoding major capsid protein L1 of human papilloma virus, which is capable, after transduced into a yeast cell, of efficiently expressing the major capsid protein L1 of human papilloma virus. The present invention also discloses an immunogenic macromolecule which is essentially produced by expression of said codon-optimized gene encoding the major capsid protein L1 of human papilloma virus in a yeast cell. The present invention further discloses the use of said immunogenic macromolecule and a composition comprising said immunogenic macromolecule.