Abstract: The present invention relates to a pharmaceutical composition for preventing and/or treating neurodegenerative diseases. On the one hand, the active ingredient C21 steroid saponin of the pharmaceutical composition can significantly reduce the generation of an amyloid ?-protein in N2a-APP695 cells and increase the clearance of excess A3; and on the other hand, the active ingredient C21 steroid saponin of the pharmaceutical composition can promote the proliferation of neuron cells, and has a protective effect on the neuronal cytotoxicity induced by neurotransmitters such as glutamate caused by the excessive accumulation of A3, thereby comprehensively playing a role in the treatment of neurodegenerative diseases. Therefore, the pharmaceutical composition has good application prospects in the preparation of an A3 formation inhibitor and a neuroprotective agent, and in drugs for preventing or treating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Huntington's disease.

Abstract: The present disclosure belongs to the technical field of plant genetic engineering. An objective of the present disclosure is to increase an anthocyanidin content of a rice seed. The present disclosure provides use of ZlMYB1 and ZlMYB2 genes from Zizania latifolia in increasing an anthocyanidin content of a rice seed, where the ZlMYB1 gene has the nucleotide sequence set forth in SEQ ID NO: 1; and the ZlMYB2 gene has the nucleotide sequence set forth in SEQ ID NO: 2. In the present disclosure, the ZlMYB1 and ZlMYB2 genes can be effectively overexpressed in rice. When a growth environment is consistent with that of a control plant, rice seeds from a rice plant overexpressing the ZlMYB1 and ZlMYB2 genes turn black and have a significantly increased anthocyanidin content compared with those from the control plant.

Abstract: A method of ctDNA library construction and sequencing data analysis for simultaneously detecting multiple common mutations in liver cancer. The library construction method and sequencing data analysis process have the following advantages: 1. Simultaneous detection of multiple mutation forms in liver cancer without capturing; 2. Suitable for efficient capture of ultra-small target regions; 3. The library may support 10-20 tests; 4. Ligate the DNA barcode to the starting ctDNA molecule during the library construction process, and cooperate with the biological information analysis process to achieve high specific detection of low-frequency mutations in ctDNA; 5. The library is usable for PCR hot spots detection and sequencing by a capture method at the same time, the added DNA barcode may effectively filter out false positive mutations and achieve high-specificity sequencing based on duplex.

Abstract: An exemplary method for buffering an image into a buffer device includes following steps: checking a first predetermined criterion; when the first predetermined criterion is not met, converting at least a first image in the buffer device into at least a corresponding second image in the buffer device, wherein a size of the corresponding second image is smaller than a size of the first image; and when the first predetermined criterion is met, storing a third image derived from the image into the buffer device.