Abstract: The present invention belongs to the field of medicine. Provided is a pharmaceutical composition for enhancing the anti-tumor effect of an EZH2 inhibitor. The pharmaceutical composition comprises an EZH2 inhibitor and a PPAR?agonist, wherein the PPAR? agonist enhances the anti-solid tumor effect of the EZH2 inhibitor. Further provided in the present invention are a related preparation of the pharmaceutical composition and the use thereof in the preparation of an anti-tumor drug. Experimental results show that when the EZH2 inhibitor GSK126 and the PPAR? agonist fenofibrate are used in combination to treat B16F10 cells, SMMC7721 cells and GL261 cells, it is found that the use thereof in combination with fenofibrate can significantly enhance the inhibitory effect of GSK126 on cell proliferation.

Abstract: A grating regulating device is applied to a 3D displaying device. The 3D displaying device includes a display panel, the display panel includes a first polarizing unit, the grating regulating device is provided on one side of the display panel away from the first polarizing unit, and the grating regulating device includes: a first substrate and a second substrate, wherein the first substrate and the second substrate face each other; a second polarizing unit provided on one side of the second substrate away from the first substrate; and a third polarizing unit provided on one side of the first substrate away from the second substrate; and an absorption axis of the first polarizing unit and an absorption axis of the second polarizing unit are perpendicular, and the absorption axis of the second polarizing unit and an absorption axis of the third polarizing unit are perpendicular.

Abstract: This application provides a battery cell, a battery, and an electric device. The battery cell includes: an electrode assembly; a housing, where the housing has a first opening for accommodating the electrode assembly; an end cover configured to cover the first opening, where the end cover has a protruding structure, the protruding structure protrudes along a first direction away from the interior of the battery cell, and the first direction is a thickness direction of the end cover; and an electrode terminal, where the electrode terminal has a protruding portion protruding from the protruding structure along a second direction, and the second direction is perpendicular to the first direction. The battery cells are interconnected in the second direction through the protruding portions of the electrode terminals, which can enhance the strength of the connection between the battery cells.

Abstract: Systems and methods for providing application-layer characterization is disclosed. Quick User Datagram Protocol (UDP) Internet Connection (QUIC) is an end-to-end encrypted, transport-layer protocol, with a goal to improve communication security and quality of experience (QoE) towards end-users. The systems and methods disclosed herein relate to estimating application-level traffic attributes without decrypting QUIC packets. Based on size, timing, and direction information available in the encrypted packet, the system analyzes associated network traffic to infer an identity of each request and response pair, including time, size, and request-response match, as well as multiplexing feature in each QUIC connection. In the case of request and response multiplexing, several requests will be gathered and matched as a group with their corresponding responses, to form a super request-response pair.

Abstract: The present disclosure belongs to the technical field of plant genetic engineering. An objective of the present disclosure is to increase an anthocyanidin content of a rice seed. The present disclosure provides use of ZlMYB1 and ZlMYB2 genes from Zizania latifolia in increasing an anthocyanidin content of a rice seed, where the ZlMYB1 gene has the nucleotide sequence set forth in SEQ ID NO: 1; and the ZlMYB2 gene has the nucleotide sequence set forth in SEQ ID NO: 2. In the present disclosure, the ZlMYB1 and ZlMYB2 genes can be effectively overexpressed in rice. When a growth environment is consistent with that of a control plant, rice seeds from a rice plant overexpressing the ZlMYB1 and ZlMYB2 genes turn black and have a significantly increased anthocyanidin content compared with those from the control plant.

Abstract: A battery cell, a battery and an electricity-consuming apparatus are provided by the present application. The battery cell includes an electrode assembly including an electrode main body that includes an electrode sheet and a separator stacked with each other, and an electrode tab extending from an end face of the electrode main body; and an infiltrating film including a first end and a second end arranged opposite to each other in a length direction thereof, in which the second end is connected to the separator, and the first end extends beyond the electrode main body.

Abstract: Devices, systems, methods, and techniques are disclosed herein for automatic testing with feature tags trained by machine learning for updates in version control systems. An example method includes deploying multiple updates in a code repository of a version control system and mapping the multiple updates using multiple feature labels. The multiple feature labels have been trained in a machine learning model to represent corresponding functional features. A processing device then identifies a subset of codes in the code repository. The subset of codes in the code repository is functionally affected by the multiple updates and is identified based on the multiple feature labels. The processing device performs a verification job on each of the subset of codes in the code repository in preparation for committing the multiple updates in the code repository.

Abstract: The present invention relates to a specific binding protein targeting PD-L1 and CD73, wherein the specific binding protein is capable of specifically binding to PD-L1 and/or a fragment thereof, and CD73 and/or a fragment thereof. The present invention further relates to use of the specific binding protein in the treatment, prevention and/or diagnosis of diseases such as immune diseases, acute and chronic inflammatory diseases, and tumor diseases.

Abstract: A display substrate and a display device are disclosed. The display substrate includes a base substrate and a plurality of sub-pixels located thereon. Each sub-pixel includes a pixel circuit and a pixel electrode electrically connected thereto, and each pixel circuit includes a driving sub-circuit. The pixel electrode includes a main electrode part and a first electrode extension part extending therefrom. The display substrate includes first type of sub-pixels. The main electrode part of each sub-pixel of the first type of sub-pixels is not overlapped with a control electrode of the driving sub-circuit of the sub-pixel or an electrode part directly electrically connected to the control electrode, and the first electrode extension part of each pixel electrode is at least partially overlapped with the control electrode or the electrode part. The first type of sub-pixels include at least two sub-pixels configured to emit light of different colors.

Abstract: A system including one or more processors and one or more non-transitory computer-readable media storing computing instructions configured to run on the one or more processors and perform: tracking touchpoints by a user over a first time period; after receiving an order, determining, using a machine-learning model, a respective contribution of each of the touchpoints, wherein the machine-learning model is trained to predict a probability of the user placing the order during a second time period based on an input feature vector representing a set of touchpoints; and allocating a respective percentage of credit for the order to the each of the touchpoints based on the respective contributions of the each of the touchpoints. Other embodiments are disclosed.

Abstract: Provided is a pixel structure. The pixel structure includes: a first electrode, a second electrode, and a liquid crystal layer that are disposed on one side of a substrate and successively stacked, wherein one of the first electrode and the second electrode is a pixel electrode and the other of the first electrode and the second electrode is a common electrode, and the second electrode includes a plurality of electrode branches sequentially arranged in a first direction, wherein each of the electrode branches includes a first end portion, a body portion, and a second end portion that are successively connected in a second direction, the body portion including at least one body segment.

Abstract: The present disclosure provides a display module, a display panel thinning method, a display panel, and a display device. The display module provided by the present disclosure includes: a display panel, a protective film located on a to-be-protected face of the display panel, a first anti-acid film located on the protective film, a second anti-acid film located on the first anti-acid film, and a sealant.

Abstract: A display substrate (20) and a display device (40). The display substrate (20) comprises a base substrate and a plurality of sub-pixels (100) located on the base substrate. Each sub-pixel (100) comprises a pixel circuit and a pixel electrode (134) electrically connected to the pixel circuit, and each pixel circuit comprises a driving sub-circuit. The pixel electrodes (134) each comprises an electrode body part (140) and a first electrode extension part (142) extending from the electrode body part (140). The display substrate (20) comprises first-type sub-pixels. The electrode body part (140) of each first-type sub-pixel (100) does not overlap a control electrode of the driving sub-circuit of the sub-pixel or an electrode part directly electrically connected to the control electrode, and the first electrode extension part (142) of each pixel electrode (134) at least partially overlaps the control electrode or the electrode part.

Abstract: The present disclosure provides a display panel, including: a first panel and a second panel opposite to the first panel; the first panel includes: gate lines extending along a first direction and data lines extending along a second direction, and the gate lines and the data lines intersect to define pixel regions; the second panel includes: a plurality of support column periodic units arranged in an array along the first direction and the second direction, each support column periodic unit includes a plurality of support columns, and at least a part of the support columns each satisfy: a connection line between the support column and a support column closest thereto extends along a third direction, and an included angle between the third direction and the first direction is not equal to 0°. The present disclosure further provides a display device.

Abstract: A display substrate (20) and a display device (40). The display substrate (20) comprises a base substrate and a plurality of sub-pixels (100) located on the base substrate. Each sub-pixel (100) comprises a pixel circuit and a pixel electrode (134) electrically connected to the pixel circuit, and each pixel circuit comprises a driving sub-circuit. The pixel electrodes (134) each comprises an electrode body part (140) and a first electrode extension part (142) extending from the electrode body part (140). The display substrate (20) comprises first-type sub-pixels. The electrode body part (140) of each first-type sub-pixel (100) does not overlap a control electrode of the driving sub-circuit of the sub-pixel or an electrode part directly electrically connected to the control electrode, and the first electrode extension part (142) of each pixel electrode (134) at least partially overlaps the control electrode or the electrode part.

Abstract: The present invention discloses a method for constructing and optimizing a molecular structure model of lignite, comprising: collecting and processing a lignite sample, analyzing a lignite experimental sample, calculating the number of carbon atoms in lignite and the number of carbon atoms in other parameters, obtaining the sizes of aromatic clusters, and determining the composition features and number of aromatic structural units in lignite; calculating the total number of carbon atoms and the number of aliphatic carbon atoms in lignite; obtaining the categories and number of oxygen-containing functional groups in lignite based on the contents of aromatic hydrocarbon, aliphatic hydrocarbon and various oxygen-containing functional groups, and designing the structural forms of nitrogen and sulfur; constructing a molecular structure model of lignite.

Abstract: A display panel, a method for detecting a display panel and an electronic device are provided. a display panel are provided, including a display area and a peripheral region surrounding the display area; a plurality of bonding pads in the peripheral region; a lighting pad in the peripheral region; a plurality of source signal lines at least in the display region; a plurality of source signal line leads in the peripheral region and electrically connected to the plurality of source signal lines and electrically connected to the plurality of bonding pads; a plurality of sub-pixel columns in the display region and electrically connected to the plurality of source signal lines; and a detection circuit, arranged in the peripheral region and between the plurality of binding pads and the display area.

Abstract: A display substrate includes an underlay substrate, a test signal access pin layer, and a signal access pin layer. The underlay substrate includes a display region and a border region at a periphery of the display region. The border region includes a signal access region at one side of the display region and at least one test signal access region adjacent to the signal access region. The test signal access pin layer is in the at least one test signal access region. The signal access pin layer is in the signal access region. A height difference between a surface of the test signal access pin layer away from the underlay substrate and a surface of the signal access pin layer away from the underlay substrate is greater than 0.

Abstract: The present invention discloses a process for improving the fluidity of palbociclib isethionate and a composition, and belongs to the field of pharmaceutical preparations. The process includes a step of conducting granulation on palbociclib isethionate and pharmaceutically acceptable auxiliary materials to obtain granules with a tap density of 0.55-0.72 g/mL and an angle of repose of less than or equal to 44°. According to the process of the present invention, the palbociclib isethionate composition has good granular fluidity during filling of capsules, and prepared palbociclib isethionate capsules have uniform content, good stability and controllable quality. A preparation method is convenient to operate and easy to understand and adjust, and has good controllability in expanded production.