Patents by Inventor Qichao RUAN

Qichao RUAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enamel Repair Visualization and Quantification
    Publication number: 20240201173
    Abstract: The present invention relates to methods for visualizing and quantifying the repair of tooth enamel, for example, for the evaluation of dentifrice compositions for the treatment or prevention of dental caries, early erosive damage, and enamel demineralization, and the promotion of enamel repair and remineralization.
    Type: Application
    Filed: December 19, 2023
    Publication date: June 20, 2024
    Applicant: Colgate-Palmolive Company
    Inventors: Qichao RUAN, Stacey Lavender
  • ORAL CARE COMPLEXES AND COMPOSITIONS
    Publication number: 20230201101
    Abstract: The present invention relates to a polyelectrolyte complex, and compositions thereof, for use in the treatment or prevention of dental caries, early erosive damage, and enamel demineralization, and the promotion of enamel repair and remineralization. This oral care composition comprises polyelectrolyte complexes comprising cationic polymers and anionic carboxylates.
    Type: Application
    Filed: December 19, 2022
    Publication date: June 29, 2023
    Applicant: Colgate-Palmolive Company
    Inventors: Qichao Ruan, Stacey Lavender
  • Oral Care Compositions
    Publication number: 20230038764
    Abstract: Disclosed herein are oral care compositions comprising hydroxyapatite and hydroxyethylcellulose as well as methods of reducing or inhibiting enamel erosion, repairing enamel erosion damage, and/or increasing enamel microcrack resistance using these compositions.
    Type: Application
    Filed: July 20, 2022
    Publication date: February 9, 2023
    Applicant: Colgate-Palmolive Company
    Inventors: Dennis ZHANG, Luciana RINAUDI MARRON, Stacey LAVENDER, Alice NG, Qichao RUAN
  • Oral Care Compositions
    Publication number: 20230045410
    Abstract: Disclosed herein are oral care compositions comprising hydroxyapatite and a basic amino acid as well as methods of reducing or inhibiting enamel erosion, repairing enamel erosion damage, and/or increasing enamel microcrack or microscratch resistance using these compositions.
    Type: Application
    Filed: July 20, 2022
    Publication date: February 9, 2023
    Applicant: Colgate-Palmolive Company
    Inventors: Dennis ZHANG, Luciana RINAUDI MARRON, Stacey LAVENDER, Zoe SCOULLOS, Yun XU, Qichao RUAN
  • Oral Care Compositions
    Publication number: 20230039655
    Abstract: Disclosed herein are oral care compositions comprising hydroxyapatite and a silica abrasive as well as methods of reducing or inhibiting enamel erosion, repairing enamel erosion damage, increasing enamel microcrack resistance and/or increasing enamel microscratch resistance using these compositions.
    Type: Application
    Filed: July 20, 2022
    Publication date: February 9, 2023
    Applicant: Colgate-Palmolive Company
    Inventors: Dennis ZHANG, Luciana RINAUDI MARRON, Stacey LAVENDER, Gokul GOVINDARAJU, Qichao RUAN
  • Method of Evaluating the Enamel Microcrack Resistance Efficacy of Compositions
    Publication number: 20230042124
    Abstract: Disclosed are methods of determining enamel micro-crack and/or microscratch resistance and also methods of identifying compositions that are effective in increasing enamel micro-crack and/or microscratch resistance or evaluating the efficacy of compositions in increasing enamel micro-crack and/or microscratch resistance.
    Type: Application
    Filed: July 20, 2022
    Publication date: February 9, 2023
    Applicant: Colgate-Palmolive Company
    Inventors: Qichao RUAN, Stacey LAVENDER
  • CHITOSAN -AMELOGENIN HYDROGEL FOR IN SITU ENAMEL GROWTH
    Publication number: 20190060207
    Abstract: A composition for re-constructing enamel-coated substrates such as a tooth which includes an amelogenin, chitosan, and water. The composition may also include compounds providing calcium and phosphate ions. Methods using the composition are also provided.
    Type: Application
    Filed: November 8, 2018
    Publication date: February 28, 2019
    Inventors: Janet Moradian-Oldak, Qichao Ruan
  • AMELOGENIN-CHITOSAN HYDROGEL FOR DENTIN HYPERSENSITIVITY
    Publication number: 20180236130
    Abstract: A method to regrow a protective layer over exposed/demineralized dentin that includes a step of identifying a subject having exposed/demineralized dentin. The demineralized dentin is contacted with a remineralization composition that includes an amelogenin and derived peptides, a chitosan, water, and a sufficient amount of a pH adjusting component such that the composition has a pH greater than about 6.0 such that dentinal tubules are occluded with apatite crystals and enamel is regrown on the dentinal tubules.
    Type: Application
    Filed: April 13, 2018
    Publication date: August 23, 2018
    Inventors: JANET MORADIAN-OLDAK, QICHAO RUAN, KAUSHIK MUKHERJEE
  • Amelogenin-chitosan hydrogel for dentin hypersensitivity
    Patent number: 9962465
    Abstract: A method to regrow a protective layer over exposed/demineralized dentin that includes a step of identifying a subject having exposed/demineralized dentin. The demineralized dentin is contacted with a remineralization composition that includes an amelogenin and derived peptides, a chitosan, water, and a sufficient amount of a pH adjusting component such that the composition has a pH greater than about 6.0 such that dentinal tubules are occluded with apatite crystals and enamel is regrown on the dentinal tubules.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: May 8, 2018
    Assignee: University of Southern California
    Inventors: Janet Moradian-Oldak, Qichao Ruan, Kaushik Mukherjee
  • ASSEMBLY OF LAYERED MONETITE-CHITOSAN NANOCOMPOSITE AND ITS TRANSITION TO ORGANIZED HYDROXYAPATITE
    Publication number: 20170273793
    Abstract: A multilayer structure that functions as a bone replacement material includes a plurality of organic matrix layers such that each organic matrix layer includes chitosan and a dicarboxylic acid. The multilayer structure also includes a plurality of calcium phosphate-containing layers wherein each calcium phosphate-containing layer is interposed between a pair of organic matrix layers. Characteristically, the chitosan is cross-linked by the dicarboxylic acid.
    Type: Application
    Filed: March 22, 2017
    Publication date: September 28, 2017
    Inventors: JANET MORADIAN-OLDAK, QICHAO RUAN
  • AMELOGENIN-CHITOSAN HYDROGEL FOR DENTIN HYPERSENSITIVITY
    Publication number: 20170007737
    Abstract: A method to regrow a protective layer over exposed/demineralized dentin that includes a step of identifying a subject having exposed/demineralized dentin. The demineralized dentin is contacted with a remineralization composition that includes an amelogenin and derived peptides, a chitosan, water, and a sufficient amount of a pH adjusting component such that the composition has a pH greater than about 6.0 such that dentinal tubules are occluded with apatite crystals and enamel is regrown on the dentinal tubules.
    Type: Application
    Filed: July 6, 2016
    Publication date: January 12, 2017
    Inventors: JANET MORADIAN-OLDAK, QICHAO RUAN, KAUSHIK MUKHERJEE
  • Chitosan -Amelogenin Hydrogel for In Situ Enamel Growth
    Publication number: 20140186273
    Abstract: A composition for re-constructing enamel-coated substrates such as a tooth which includes an amelogenin, chitosan, and water. The composition may also include compounds providing calcium and phosphate ions. Methods using the composition are also provided.
    Type: Application
    Filed: December 27, 2013
    Publication date: July 3, 2014
    Applicant: University of Southern California
    Inventors: Janet MORADIAN-OLDAK, Qichao RUAN