Abstract: The present disclosure relates to the field of medicinal chemistry, in particular to a phenyl triazole MLL1-WDR5 protein-protein interaction inhibitor (I) and a preparation method thereof, and pharmacodynamics experiments prove that the compound of the present disclosure has relatively strong MLL1-WDR5 protein-protein interaction inhibition activity.

Abstract: The present invention discloses a bevel swing head interpolation tool changing mechanism, which includes a bed, a sliding table, a column, a ram, a swing head and a tool magazine, in which the swing head moves along the X-axis, Y-axis and Z-axis of the machine tool, the axis of the swing head and a B-axis form an included angle between 30°-60°, the tool magazine is equipped with a tool, and the swing head moves along its own axis direction and change the tool. The invention provides a bevel swing head interpolation tool changing mechanism and a method thereof, capable of quick and convenient tool changing through the mutual cooperation of the movement of the linear axes of the machine tool, without complex equipment such as manipulators used, and which is simple in structure, good in stability and easy to maintain.

Abstract: The present invention discloses a multi-degree-of-freedom numerical control turntable including: a B-shaft rotating assembly; a C1-shaft workbench swing assembly; a C2-shaft workbench rotating assembly; and an S-shaft workbench movement assembly. The B-shaft rotating assembly includes a rotating connection land and a B-shaft power control mechanism; the C2-shaft workbench rotating assembly includes a movement base, a workbench and a C2-shaft power control mechanism; the S-shaft workbench movement assembly includes a swing base and an S-shaft power control mechanism; and the C1-shaft workbench swing assembly includes a swing arm and a C1-shaft power control mechanism, with the C1-shaft line intersecting the B-shaft line. The S-shaft power control mechanism can drive the movement base to move along an S-shaft line on the swing base to cause a region to be machined of a workpiece to approach the intersection point of the C1-shaft line and the B-shaft line.

Abstract: A system and method of providing a broadband patch antenna includes a main patch having a first strip and a second strip positioned about a ground strip extending from a ground plane, wherein at least a portion of the first strip of the main patch is disposed above the ground strip and forms a first radiating edge with the ground strip, and at least a portion of the second strip of the main patch is disposed below the ground strip and forms a second radiating edge with the ground plane. A parasitic patch is coupled to the main patch along at least a portion of a non-radiating edge of the main patch, and the parasitic patch includes a first strip and a second strip, wherein at least a portion of the first strip of the parasitic patch is disposed above the ground strip and at least a portion of the second strip of the parasitic patch is disposed below the ground strip.

Abstract: A system and method of providing a broadband patch antenna includes a main patch having a first strip and a second strip positioned about a ground strip extending from a ground plane, wherein at least a portion of the first strip of the main patch is disposed above the ground strip and forms a first radiating edge with the ground strip, and at least a portion of the second strip of the main patch is disposed below the ground strip and forms a second radiating edge with the ground plane. A parasitic patch is coupled to the main patch along at least a portion of a non-radiating edge of the main patch, and the parasitic patch includes a first strip and a second strip, wherein at least a portion of the first strip of the parasitic patch is disposed above the ground strip and at least a portion of the second strip of the parasitic patch is disposed below the ground strip.