Abstract: Provided is method of extracting and separating gallium by emulsion liquid membrane. The method of extracting and separating gallium by emulsion liquid membrane includes preparation of the emulsion liquid membrane, extraction and deextraction. By establishing a proper emulsion liquid membrane system, gallium is selectively extracted from the gallium leaching solution. In the scheme of the present disclosure, chosen factors are optimized through fractional fractorial design and central composite design so as to obtain an optimal processing scheme. The influences of gallium solution/emulsion volume ratio, extractant concentration, H2SO4 concentration, emulsion stirring duration and emulsion stirring speed on the gallium extraction rate are studied, and efficient enrichment of gallium is achieved.

Abstract: Provided herein are a crystal form of an isobutyrate nucleoside compound, and a preparation method. The crystal form is III; the X-ray powder diffraction pattern thereof has characteristic peaks at diffraction angles, 2?, 8.47±0.2°, 16.87±0.2°, 17.47±0.2°, 22.13±0.2° and 28.66±0.2°. The crystal form III has good physical and chemical stability. The preparation method for the crystal form is simple to operate and high in repeatability.

Abstract: The present invention provides a crystalline form of a nucleoside compound. The crystalline form is ATV014 crystalline form I, which has good solubility and thermal stability, and better bioavailability and dissolution profile in specific formulations. The good permeability and thermal stability of the crystalline form make it suitable for use in specific pharmaceutical formulations.

Abstract: The present invention provides novel crystalline forms of a nucleoside compound and salts thereof, which belongs to the technical field of medicines. The nucleoside compound is compound ATV014. The present invention focuses on investigating whether compound ATV014 has multiple solid forms. Surprisingly, it is discovered that compound ATV014 exists in a variety of stable solid forms, comprising: ATV-014 free base crystalline form I, ATV-014 hydrochloride crystalline form I, ATV-014 hydrochloride crystalline form II, ATV-014 hydrochloride crystalline form III, ATV-014 hydrochloride crystalline form IV, ATV-014 hydrobromide crystalline form I, and ATV-014 p-toluenesulfonate crystalline form I.

Abstract: Provided are methods for treating coronavirus infections by administering modified nucleosides, ester and amino acid ester prodrugs of nucleoside, their pharmaceutically acceptable salts, and drug combination thereof, of Formula (I). The compounds, combination, and methods provided are particularly useful for preventing, mitigating, or treating coronavirus infections or cytopathic effects resulting from the replication or reproduction of coronaviruses and their variants, including SARS-CoV-2.

Abstract: Embodiments of wearable electronic devices in game play applications are described. In an embodiment a method may include receiving a signal characteristic of movement of a MEMS inertial sensor (202) configured to generate data in response to movement of a human foot. The method may also include processing the signal received from the MEMS inertial sensor (202), in a processing device (203), to generate a command input for an application processing device (206, 208, 210, 212). Additionally, the method may include communicating the command input to the application processing device (206, 208, 210, 212) for control of an application hosted on the application processing device.