Patents by Inventor Qifang Li

Qifang Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240140937
    Abstract: Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
    Type: Application
    Filed: November 28, 2023
    Publication date: May 2, 2024
    Applicant: Pfizer Inc.
    Inventors: Markus Boehm, Shawn Cabral, Matthew S. Dowling, Kentaro Futatsugi, Kim Huard, Esther Cheng Yin Lee, Allyn T. Londregan, Jana Polivkova, David A. Price, Qifang Li
  • Patent number: 11866425
    Abstract: Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
    Type: Grant
    Filed: June 11, 2021
    Date of Patent: January 9, 2024
    Assignee: Pfizer Inc.
    Inventors: Markus Boehm, Shawn Cabral, Matthew S. Dowling, Kentaro Futatsugi, Kim Huard, Esther Cheng Yin Lee, Allyn T. Londregan, Jana Polivkova, David A. Price, Qifang Li
  • Publication number: 20210309646
    Abstract: Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
    Type: Application
    Filed: June 11, 2021
    Publication date: October 7, 2021
    Applicant: Pfizer Inc.
    Inventors: Markus Boehm, Shawn Cabral, Matthew S. Dowling, Kentaro Futatsugi, Kim Huard, Esther Cheng Yin Lee, Allyn T. Londregan, Jana Polivkova, David A. Price, Qifang Li
  • Patent number: 11034678
    Abstract: Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: June 15, 2021
    Assignee: Pfizer Inc.
    Inventors: Markus Boehm, Shawn Cabral, Matthew S. Dowling, Kentaro Futatsugi, Kim Huard, Esther Cheng Yin Lee, Allyn T. Londregan, Jana Polivkova, David A. Price, Qifang Li
  • Publication number: 20200181127
    Abstract: Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
    Type: Application
    Filed: February 18, 2020
    Publication date: June 11, 2020
    Applicant: Pfizer Inc.
    Inventors: Markus Boehm, Shawn Cabral, Matthew S. Dowling, Kentaro Futatsugi, Kim Huard, Esther Cheng Yin Lee, Allyn T. Londregan, Jana Polivkova, David A. Price, Qifang Li
  • Publication number: 20180258081
    Abstract: Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
    Type: Application
    Filed: May 11, 2018
    Publication date: September 13, 2018
    Applicant: Pfizer Inc.
    Inventors: Markus Boehm, Shawn Cabral, Matthew S. Dowling, Kentaro Futatsugi, Kim Huard, Esther Cheng Yin Lee, Allyn T. Londregan, Jana Polivkova, David A. Price, Qifang Li
  • Patent number: 10071992
    Abstract: Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: September 11, 2018
    Assignee: Pfizer Inc.
    Inventors: Markus Boehm, Shawn Cabral, Matthew S. Dowling, Kentaro Futatsugi, Kim Huard, Esther Cheng Yin Lee, Allyn T. Londregan, Jana Polivkova, David A. Price, Qifang Li
  • Publication number: 20180051012
    Abstract: Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
    Type: Application
    Filed: August 11, 2017
    Publication date: February 22, 2018
    Applicant: Pfizer Inc.
    Inventors: Markus Boehm, Shawn Cabral, Matthew S. Dowling, Kentaro Futatsugi, Kim Huard, Esther Cheng Yin Lee, Allyn T. Londregan, Jana Polivkova, David A. Price, Qifang Li
  • Publication number: 20160051582
    Abstract: A pharmaceutical composition for treatment of chronic pain includes lidocaine, glucose, sodium chloride and sodium bicarbonate. The pharmaceutical composition could be applied for treatment of chronic pains in local position such as soft tissue, muscle tendon, synovial bursa.
    Type: Application
    Filed: March 16, 2015
    Publication date: February 25, 2016
    Inventors: QIFANG LI, HUA KANG, HONG JIANG
  • Patent number: 9218393
    Abstract: A hierarchical data server provides a query and storage system for hierarchical data with three interfaces that are, data interface for accepting hierarchical data, query interface for accepting a query, and result interface for returning output of the query. The system models hierarchical data with one data object called data vine and one data structure type called data vine list. A data vine includes a name, a property list, and a child list. A data vine list is an ordered list of data vines. A data vine is recursively defined with its child list as a data vine list. The system introduces five basic operators, cast, restrict, unique, sort, and traverse. Each operator acts on one data vine list and returns another data vine list. A property list in a data vine is unordered with set operations implemented, which include default operation, update operation, elimination operation, replacement operation, and intersection operation.
    Type: Grant
    Filed: April 15, 2013
    Date of Patent: December 22, 2015
    Inventor: Qifang Li
  • Publication number: 20140310301
    Abstract: A hierarchical data server provides a query and storage system for hierarchical data with three interfaces that are, data interface for accepting hierarchical data, query interface for accepting a query, and result interface for returning output of the query. The system models hierarchical data with one data object called data vine and one data structure type called data vine list. A data vine includes a name, a property list, and a child list. A data vine list is an ordered list of data vines. A data vine is recursively defined with its child list as a data vine list. The system introduces five basic operators, cast, restrict, unique, sort, and traverse. Each operator acts on one data vine list and returns another data vine list. A property list in a data vine is unordered with set operations implemented, which include default operation, update operation, elimination operation, replacement operation, and intersection operation.
    Type: Application
    Filed: April 15, 2013
    Publication date: October 16, 2014
    Inventor: Qifang Li
  • Patent number: 8431597
    Abstract: The present invention relates to a compound of the Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3A, R3B, R4, R5, X, m, and n are as defined herein. Such novel benzamidazole derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: April 30, 2013
    Assignee: Pfizer Inc.
    Inventors: Michael J. Munchhof, Lawrence A. Reiter, Susan D. La Greca, Christopher S. Jones, Qifang Li
  • Publication number: 20120157495
    Abstract: The present invention relates to a compound of the Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3A, R3B, R4, R5, X, m, and n are as defined herein. Such novel benzamidazole derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: February 24, 2012
    Publication date: June 21, 2012
    Inventors: Michael J. MUNCHHOF, Lawrence A. Reiter, Susan D. La Greca, Christopher S. Jones, Qifang Li
  • Patent number: 8148401
    Abstract: The present invention relates to a compound of the Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3A, R3B, R4, R5, X, m, and n are as defined herein. Such novel benzamidazole derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: April 3, 2012
    Assignee: Pfizer Inc.
    Inventors: Michael J. Munchhof, Lawrence A. Reiter, Susan D. La Greca, Christopher S. Jones, Qifang Li
  • Publication number: 20100029615
    Abstract: The present invention relates to a compound of the formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, A, X, n, and are as defined herein. Such novel benzamidazole derivatives are useful in trv treatment of abnormal cell growth, such as cancer, in mammals. This invention ate relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing sue compounds.
    Type: Application
    Filed: December 5, 2007
    Publication date: February 4, 2010
    Inventors: Michael John Munchhof, Lawrence Alan Reiter, Andrei Shavnya, Christopher Scott Jones, Qifang Li, Robert Gerald Linde ll
  • Publication number: 20090005416
    Abstract: The present invention relates to a compound of the Formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3A, R3B, R4, R5, X, m, and n are as defined herein. Such novel benzamidazole derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: June 19, 2008
    Publication date: January 1, 2009
    Inventors: Michael J. Munchhof, Lawrence A. Reiter, Susan D. La Greca, Christopher S. Jones, Qifang Li
  • Patent number: 6701516
    Abstract: P++ software that provides a Prolog language data storing and processing method, includes making a plurality of different application programs, introduces two structure types into arguments of clauses, implements these two structure types in predicate inputting, memory storing, processing through unification and back tracking, and outputting for each query. The first structure type is hierarchically defined and recursively processed. Its member can be a variable, a data term, or of any other structure type except itself. Its variable child member can be substituted by one of this structure type making a result in the same structure type with different length. The second structure type is recursively defined and processed. Its member can be a variable, a data term, or of any structure type including itself. It has fixed number of members. With these two structure types, addition and multiplication are extended to multi-dimensional space operations.
    Type: Grant
    Filed: June 28, 2000
    Date of Patent: March 2, 2004
    Inventor: Qifang Li