Patents by Inventor Qihui Wang
Qihui Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240398893Abstract: The invention relates to an anti-coronavirus polypeptide as well as derivatives and application thereof, provides the anti-coronavirus polypeptide, and provides cholesterol-containing derivatives of the polypeptide on the basis of the anti-coronavirus polypeptide. Particularly, the original strain and the variant strain of the SARS-COV-2 have an unexpected inhibition effect, can be used for preparing medicines or vaccines for preventing or treating the new coronavirus, and have great prevention or treatment potential.Type: ApplicationFiled: June 27, 2024Publication date: December 5, 2024Applicants: Institute of Microbiology, Chinese Academy of Sciences, Hybio Pharmaceutical Co., Ltd.Inventors: Fu GAO, Shaogui ZENG, Qihui WANG, Yangming TANG, Jiantao CHEN, Lili WU, Anqi ZHENG
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Publication number: 20240262894Abstract: Provided in the present disclosure is an antibody or an antigen-binding fragment thereof that binds to the respiratory syncytial virus F protein. Further provided in the present disclosure is the use of the antibody or the antigen-binding fragment thereof in the preparation of a drug for the treatment and/or prevention of RSV infections.Type: ApplicationFiled: June 13, 2022Publication date: August 8, 2024Inventors: Fu GAO, Lianpan DAI, Jian SONG, Senyu XU, Qihui WANG
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Publication number: 20240228547Abstract: The present application relates to a polypeptide for preventing or treating a novel coronavirus and an application thereof. The polypeptide is P3 polypeptide and any one of P3-1 polypeptide, P3-2 polypeptide, P3-3 polypeptide, P3-4 polypeptide, and P3-5 polypeptide derived from the P3 polypeptide. The amino acid sequences of the P3 polypeptide, the P3-1 polypeptide, the P3-2 polypeptide, the P3-3 polypeptide, the P3-4 polypeptide, and the P3-5 polypeptide are respectively shown in SEQ ID NOs: 1-6. The polypeptide of the present application has a strong inhibitory effect on original strains and a plurality of variant strains of the novel coronavirus, and can be used for preparing a drug or a vaccine for preventing and/or treating diseases caused by the novel coronavirus. The polypeptide is expected to also have the potential of preventing and/or treating new variant strains appearing in the future and sarbecovirus.Type: ApplicationFiled: February 14, 2024Publication date: July 11, 2024Inventors: Fu GAO, Qihui Wang, Lili Wu, Anqi Zheng, Huan Sun, Yan Chai, Pengcheng Han
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Publication number: 20240173395Abstract: Provided in the present disclosure are a Zika/dengue vaccine and its application thereof. The present disclosure introduces a mutation into the E-protein FL fusion region of the Zika virus or dengue virus. Antigens with said mutations are unable to bind to antibodies that causes ADE. After immunization with the vaccine of the present disclosure acquired from the said antigens, production of FL epitope-induced antibodies can be prevented, thereby reducing or eliminating the ADE effect.Type: ApplicationFiled: November 9, 2020Publication date: May 30, 2024Applicant: Institute of Microbiology, Chinese Academy of SciencesInventors: Fu GAO, Lianpan DAI, Jinghua YAN, Kun XU, Yuxuan HAN, Qihui WANG, Qingrui HUANG, Jinhe LI
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Publication number: 20230073067Abstract: Provided in the present invention are a humanized monoclonal antibody for the 2019 novel coronavirus (2019-nCOV) and the use thereof. The antibody is capable of specifically binding with a receptor binding domain (RBD) of 2019-nCOV and blocking the binding between the RBD of 2019-nCOV and ACE2, and furthermore inhibiting the infection caused by 2019-nCOV.Type: ApplicationFiled: February 23, 2021Publication date: March 9, 2023Applicant: Institute of Microbiology, Chinese Academy of ScienceInventors: Jinghua YAN, Rui SHI, Qihui WANG, Fu GAO, Sufang MA
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Publication number: 20210140401Abstract: Disclosed is a power-adjustable wave power generator, comprising a support platform (1), a power generator (2), a rotary shaft (3), an impeller rod (4), a blade frame (6), blades (7), a synchronous movement mechanism and a lifting mechanism. The power generator (2) is arranged on the support platform (1) and connected to the support platform (1). The impeller rod (4) is radially connected to the rotary shaft (3). The blade frame (6), which is provided with several blades (7), is slidably connected to the impeller rod (4). The synchronous movement mechanism adjusts the distance of the frame (6) relative to the rotary shaft (3). The lifting mechanism adjusts the angle of the blades. The power generator can not only effectively generate power under the condition of small waves, but also can adjust extracted energy according to a full load of power generation when a wave force remains unchanged, and can automatically prevent a disaster under the condition of a catastrophic climate.Type: ApplicationFiled: October 24, 2018Publication date: May 13, 2021Inventors: Shiyao FAN, Yingjing LIANG, Ning LV, Lin FAN, Qihui WANG, Huanjing YAN, Huijing LIANG, Dongdong WU, Lianbao AN, Fangfang HAO, Zhiyuan GUO, Bin WEN
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Patent number: 9746728Abstract: A display panel and a display device are provided to better protect a metal connecting line area in a peripheral wiring region, improve the protection degree and prevent the wire breakage. The display panel includes a gate insulating layer (102) disposed on a gate metal layer (101); and a protective layer (103), a passivation layer (105) and an indium tin oxide (ITO) coating layer (107) disposed on the gate insulating layer in sequence. The display panel and the display device can increase the film thickness in the peripheral wiring region, and hence can protect the entire peripheral wiring region and particularly the metal connecting line area exposed outside a color filter panel and improve the protection degree.Type: GrantFiled: June 30, 2014Date of Patent: August 29, 2017Assignees: BOE Technology Group Co., Ltd., Beijing BOE Display Technology Co., Ltd.Inventors: Ming Zhang, Manman Wang, Guoqiang Zhang, Chao Fan, Qihui Wang, Zhongfei Bai
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Patent number: 9694396Abstract: The present disclosure provides a stripping apparatus including a cleaning device, a transition unit and a stripping device. The cleaning device includes a first cleaning unit, a second cleaning unit and a third cleaning unit. The stripping device is connected with the transition unit; the transition unit is further connected with the first cleaning unit; the first cleaning unit is further connected with the second cleaning unit; the second cleaning unit is further connected with the third cleaning unit. Temperatures of the first cleaning unit, the second cleaning unit and the third cleaning unit are gradually decreased. The temperature of the third cleaning unit is equal to the temperature of water injected into the third cleaning unit.Type: GrantFiled: October 20, 2014Date of Patent: July 4, 2017Assignees: BOE TECHNOLOGY GROUP CO., LTD., BEIJING BOE DISPLAY TECHNOLOGY CO., LTD.Inventors: Zhixue Dong, Wei Li, Youngjin Song, Kai Yu, Zhongfei Bai, Qihui Wang, Yunliang Zheng, Meng Yang, Shuangqiang Zhang, Xiaoyu Shen
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Publication number: 20170110587Abstract: An array substrate and a manufacturing method thereof, a display panel, and a display device are provided. The array substrate includes a substrate; a source-drain metallic layer and a first passivation metallic protective layer formed in sequence on the substrate, the source-drain metallic layer including a source electrode and a drain electrode not contacted with each other; a conductive protection layer formed on the substrate on which the first passivation metallic protection layer has been formed; and a pixel electrode formed on the substrate on which the conductive protection layer has been formed, the pixel electrode contacting the conductive protection layer.Type: ApplicationFiled: September 1, 2016Publication date: April 20, 2017Inventors: Yao LIU, Jinchao BAI, Xiangqian DING, Huibin GUO, Xi CHEN, Qihui WANG, Jing WANG
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Publication number: 20150336137Abstract: The present disclosure provides a stripping apparatus including a cleaning device, a transition unit and a stripping device. The cleaning device includes a first cleaning unit, a second cleaning unit and a third cleaning unit. The stripping device is connected with the transition unit; the transition unit is further connected with the first cleaning unit; the first cleaning unit is further connected with the second cleaning unit; the second cleaning unit is further connected with the third cleaning unit. Temperatures of the first cleaning unit, the second cleaning unit and the third cleaning unit are gradually decreased. The temperature of the third cleaning unit is equal to the temperature of water injected into the third cleaning unit.Type: ApplicationFiled: October 20, 2014Publication date: November 26, 2015Applicants: BOE TECHNOLOGY GROUP CO., LTD., BEIJING BOE DISPLAY TECHNOLOGY CO., LTD.Inventors: ZHIXUE DONG, WEI LI, YOUNGJIN SONG, KAI YU, ZHONGFEI BAI, QIHUI WANG, YUNLIANG ZHENG, MENG YANG, SHUANGQIANG ZHANG, XIAOYU SHEN
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Publication number: 20150185570Abstract: A display panel and a display device are provided to better protect a metal connecting line area in a peripheral wiring region, improve the protection degree and prevent the wire breakage. The display panel includes a gate insulating layer (102) disposed on a gate metal layer (101); and a protective layer (103), a passivation layer (105) and an indium tin oxide (ITO) coating layer (107) disposed on the gate insulating layer in sequence. The display panel and the display device can increase the film thickness in the peripheral wiring region, and hence can protect the entire peripheral wiring region and particularly the metal connecting line area exposed outside a color filter panel and improve the protection degree.Type: ApplicationFiled: June 30, 2014Publication date: July 2, 2015Applicants: BEIJING BOE DISPLAY TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Ming Zhang, Manman Wang, Guoqiang Zhang, Chao Fan, Qihui Wang, Zhongfei Bai