Abstract: A leakage-proof electronic atomizer includes a shell, a cartridge, a second orifice plate, and a pushing component. The shell is provided with a gas channel. The gas channel includes a gas inlet at one end and a gas outlet at the other end, and the top of the shell is provided with an accommodation cavity with an upper-end opening. The cartridge is detachably arranged in the accommodation cavity, and the pushing component is configured to drive a first orifice plate to slide so that first square holes of the first orifice plate are in communication with second square holes of the second orifice plate, allowing atomized e-liquid in the cartridge to enter into the gas channel.

Abstract: A heat-not-burn cigarette includes a shell, a driving assembly, and a locking mechanism. The shell is provided with an opening and an accommodation cavity. The opening communicates the accommodation cavity with an outside world. The locking mechanism is provided in the accommodation cavity. The driving assembly is transmissively connected to the locking mechanism to drive the locking mechanism to form a smaller clamping ring and a larger clamping ring. The locking mechanism includes a bearing assembly and at least one transmission assembly. The bearing assembly is adjustably connected to the transmission assembly, and the transmission assembly is connected to the driving assembly, so as to provide preset tracks for the bearing assembly. The bearing assembly expands or contracts along the preset tracks, such that the bearing assembly is adjustably attached to a peripheral side of a cigarette body.

Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.

Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.

Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.

Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.

Abstract: The present invention relates to an azetidine derivative for use as a Janus kinase (JAK) inhibitor, a drug composition comprising same, a preparation method therefor, and a use thereof in the treatment of JAK-related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers.