Patents by Inventor Qin Liu

Qin Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS
    Publication number: 20140303231
    Abstract: The invention features therapeutic compositions comprising agents useful for the treatment or prevention of pruritis, and methods useful for identifying such agents.
    Type: Application
    Filed: January 24, 2014
    Publication date: October 9, 2014
    Applicant: The Johns Hopkins University
    Inventors: Xinzhong Dong, Qin Liu, David J. Anderson
  • Inkjet ink composition containing anti-kogation agents
    Patent number: 8770736
    Abstract: Ink compositions and methods of using the same are disclosed. An example ink composition includes an inkjet vehicle, from about 0.1 wt % to about 10 wt % of colorants, from about 0.01 wt % to about 10 wt % of anti-kogation agents, and from about 0.01 wt % to about 10 wt % of dispersed resin beads.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: July 8, 2014
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Sundar Vasudevan, Qin Liu, James P. Shields
  • Surfactants With A Terminal Dialkyl- Or Cycloalkyl-Substituted Tertiary Amine And Inks Including The Same
    Publication number: 20140118816
    Abstract: Surfactants are provided that have a hydrophobic tail portion and a hydrophilic head portion. The hydrophilic head portion includes a terminal dialkyl-substituted tertiary amine or a terminal cycloalkyl-substituted tertiary amine. Also provided are pigment-based inks employing the surfactant, a combination of an electronic display and the pigment-based inks, and a process for reducing conductivity in primary amine-based surfactants and improving reliability of electronic inks employing such surfactants.
    Type: Application
    Filed: June 10, 2011
    Publication date: May 1, 2014
    Inventors: Zhang-Lin Zhou, Qin Liu, Mary Elizabeth Parent
  • Dual color electronically addressable ink
    Patent number: 8652245
    Abstract: A dual color electronically addressable ink includes a non-polar carrier fluid; a first colorant of a first color; and a second colorant of a second color that is different than the first color. The first colorant includes a first particle core, and a first functional group attached to a surface of the particle core. The first functional group is capable of carrying a positive charge and is chosen from a base or a salt of the base. The second colorant includes a particle core, and a second functional group attached to a surface of the particle core. The second functional group is capable of carrying a negative charge and is chosen from an acid or a salt of the acid. The ink further includes an additive chosen from polyhydroxystearic amide salt, polyhydroxystearic acid, aromatic butyric acid, and combinations thereof.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: February 18, 2014
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Qin Liu, Zhang-Lin Zhou, Yaron Grinwald, Gil Bar-Haim
  • Extended Wear Ophthalmic Lens
    Publication number: 20140022507
    Abstract: A method for making a silicone hydrogel contact lens is provided. In one embodiment, a prepolymer mixture is polymerized in a lens mold in an atmosphere having less than about 10000 ppm oxygen to form a silicone hydrogel contact lens suitable for extended wear as characterized by producing less than 10% corneal swelling after a period of continuous wear of 7 days including normal sleep periods. In one embodiment, the prepolymer mixture comprises at least one oxyperm material containing hydrophilic groups, wherein the at least one oxyperm material is a siloxane-containing macromer or monomer, at least one ionperm material, and a cross-linking agent. In certain embodiments, the polymerization of the prepolymer mixture may be carried out in an atmosphere having less than about 1000 ppm oxygen.
    Type: Application
    Filed: September 23, 2013
    Publication date: January 23, 2014
    Applicant: CIBA Vision Corporation
    Inventors: Paul Clement Nicolson, Richard Carlton Baron, Peter Chabrecek, John Court, Angelika Domschke, Hans Jorge Griesser, Arthur Ho, Jens Hopken, Bronwyn Glenice Laycock, Qin Liu, Dieter Lohmann, Gordon Francis Meijs, Eric Papaspiliotopoulos, Judy Smith Riffle, Klaus Schindhelm, Deborah Sweeney, Wilson Leonard Terry, Jr., Jurgen Vogt, Lynn Cook Winterton
  • PIGMENT-BASED INKS
    Publication number: 20140016179
    Abstract: A compound is disclosed. The compound has a general structure: wherein R1, R2, and R3 are each independently selected from the group consisting of hydrogen, substituted saturated hydrocarbons, non-substituted saturated hydrocarbons, substituted unsaturated hydrocarbons, and non-substituted unsaturated hydrocarbons; wherein E and D are each independently selected from the group consisting of CH2, O, S, and NH; and wherein a, b, x, y, and z are each independently any whole number between 0 and 45, inclusive, wherein the sum of a and b is less than 45 or equal to 45 and wherein the sum of x, y, and z is less than 45 or equal to 45.
    Type: Application
    Filed: July 12, 2012
    Publication date: January 16, 2014
    Inventors: Zhang-Lin Zhou, Qin Liu
  • Extended wear ophthalmic lens
    Patent number: 8568626
    Abstract: A method for making a silicone hydrogel contact lens is provided. In one embodiment, a prepolymer mixture is polymerized in a lens mold in an atmosphere having less than about 10000 ppm oxygen to form a silicone hydrogel contact lens suitable for extended wear as characterized by producing less than 10% corneal swelling after a period of continuous wear of 7 days including normal sleep periods. In one embodiment, the prepolymer mixture comprises at least one oxyperm material containing hydrophilic groups, wherein the at least one oxyperm material is a siloxane-containing macromer or monomer, at least one ionoperm material, and a cross-linking agent. In certain embodiments, the polymerization of the prepolymer mixture may be carried out in an atmosphere having less than about 1000 ppm oxygen.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: October 29, 2013
    Assignee: CIBA Vision Corporation
    Inventors: Paul Clement Nicolson, Richard Carlton Baron, Peter Chabrecek, John Court, Angelika Domschke, Hans Jorge Griesser, Arthur Ho, Jens Hopken, Bronwyn Glenice Laycock, Qin Liu, Dieter Lohmann, Gordon Francis Meijs, Eric Papaspiliotopoulos, Judy Smith Riffle, Klaus Schindhelm, Deborah Sweeney, Wilson Leonard Terry, Jr., Jurgen Vogt, Lynn Cook Winterton
  • Cyclohexenyl modulators of chemokine receptor activity
    Patent number: 8507559
    Abstract: The present application describes modulators of MCP-1 or CCR-2 of formula, (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein T, W, X, Y, Z, R1, R2, R4 and R6, are defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula, (I) are disclosed.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: August 13, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: Percy H. Carter, Gregory D. Brown, George V. De Lucca, Douglas G. Batt, Rui-Qin Liu, Feng Qiu
  • Extended wear ophthalmic lens
    Patent number: 8415404
    Abstract: An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. In one embodiment, an ophthalmic lens is a copolymerization product of at least one oxyperm, at least one ionoperm, and a crosslinker. In one embodiment, a lens has a tensile modulus of less than about 3.0 MPa, yet in another embodiment, the tensile modulus is between about 0.5 to about 1.5 MPa.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: April 9, 2013
    Assignee: Ciba Vision Corporation
    Inventors: Paul Clement Nicolson, Richard Carlton Baron, Peter Chabrecek, John Court, Angelika Domschke, Hans Jorg Griesser, Arthur Ho, Jens Hopken, Bronwyn Glenice Laycock, Qin Liu, Dieter Lohmann, Gordon Francis Meijs, Eric Papaspiliotopoulos, Judy Smith Riffle, Klaus Schindhelm, Deborah Sweeney, Wilson Leonard Terry, Jr., Jurgen Vogt, Lynn Cook Winterton
  • DUAL COLOR ELECTRONICALLY ADDRESSABLE INK
    Publication number: 20130071690
    Abstract: A dual color electronically addressable ink includes a non-polar carrier fluid; a first colorant of a first color; and a second colorant of a second color that is different than the first color. The first colorant includes a first particle core, and a first functional group attached to a surface of the particle core. The first functional group is capable of carrying a positive charge and is chosen from a base or a salt of the base. The second colorant includes a particle core, and a second functional group attached to a surface of the particle core. The second functional group is capable of carrying a negative charge and is chosen from an acid or a salt of the acid. The ink further includes an additive chosen from polyhydroxystearic amide salt, polyhydroxystearic acid, aromatic butyric acid, and combinations thereof.
    Type: Application
    Filed: September 15, 2011
    Publication date: March 21, 2013
    Inventors: Qin Liu, Zhang-Lin Zhou, Yaron Grinwald, Gil Bar-Haim
  • Protein splicing using short terminal split inteins
    Patent number: 8394604
    Abstract: The invention provides methods of producing functional split inteins having small N-intein and/or small C-intein. Using these split inteins with their protein trans-splicing and cleavage activities, we provide new and more effective methods of manipulating proteins. They include site-specific addition of synthetic peptides at protein's terminal and internal locations, ligation of synthetic and/or expressed polypeptides, controllable cyclization of synthetic and/or expressed polypeptides, and controllable cleavages of recombinant proteins. These methods have numerous utilities including but not limited to protein fluorescence labeling, fixation on microchips, site-specific PEGylation, and linkage with pharmaceutical molecules.
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: March 12, 2013
    Inventors: Paul Xiang-Qin Liu, Kaisong Zhou, Gerrit Volkmann
  • Pigment-based inks
    Patent number: 8331014
    Abstract: A pigment-based ink includes a non-polar carrier fluid and pigment particles suspended in the non-polar carrier fluid. The pigment particles have surface functionalized anionic groups. A combination of an electronic display and an electronic ink is provided, as is a method for modifying the pigment particles.
    Type: Grant
    Filed: November 2, 2010
    Date of Patent: December 11, 2012
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Qin Liu, Zhang-Lin Zhou
  • INKS INCLUDING BLOCK COPOLYMER GRAFTED PIGMENTS VIA AZIDE CHEMISTRY
    Publication number: 20120300284
    Abstract: Pigment based inks are provided. The inks include a non-polar carrier fluid; and a surface-functionalized pigment particle including a nitrogen-inked moiety to the surface of the pigment particle through a nitrogen link at one end of the nitrogen-linked moiety and a block copolymer having at least two blocks attached at another end, the pigment particle suspended in the non-polar carrier fluid. A combination of an electronic display and an electronic ink employing the pigment and a process for making the pigment-based inks are also provided.
    Type: Application
    Filed: May 25, 2011
    Publication date: November 29, 2012
    Inventors: Zhang-Lin Zhou, Qin Liu
  • NITROGEN-LINKED SURFACE FUNCTIONALIZED PIGMENTS FOR INKS
    Publication number: 20120275012
    Abstract: A pigment-based ink is disclosed. The ink includes a non-polar carrier fluid and a nitrogen-linked surface functionalized pigment particle, wherein the nitrogen-linked surface functionalized pigment particle is suspended in the non-polar carrier fluid and includes an azide moiety linked to the surface of a pigment particle. The azide moiety further includes an acidic or a basic functional group bonded to it. An electronic display utilizing the pigment-based ink and a method of formulating the pigment-based ink are also disclosed.
    Type: Application
    Filed: April 29, 2011
    Publication date: November 1, 2012
    Inventors: Zhang-Lin Zhou, Qin Liu
  • INKS WITH FLUORINATED MATERIAL-SURFACE MODIFIED PIGMENTS
    Publication number: 20120268806
    Abstract: Pigment-based inks with fluorinated material-surface modified pigments are provided. The inks include a non-polar carrier fluid, and pigment particles suspended in the non-polar carrier fluid. The pigment particles either have fluorinated acidic functional groups, which are charged through basic charge directors to give negatively charged pigment dispersions, or have fluorinated basic functional groups, which are charged thorough acidic charge directors to give positively charged pigment dispersions. A combination of an electronic display and an electronic ink is also provided, as is a method for modifying the pigment particles.
    Type: Application
    Filed: April 21, 2011
    Publication date: October 25, 2012
    Inventors: Zhang-Lin Zhou, Jong-Souk Yeo, Qin Liu
  • INKJET INK COMPOSITION CONTAINING ANTI-KOGATION AGENTS
    Publication number: 20120249623
    Abstract: Ink compositions and methods of using the same are disclosed. An example ink composition includes an inkjet vehicle, from about 0.1 wt % to about 10 wt % of colorants, from about 0.01 wt % to about 10 wt % of anti-kogation agents, and from about 0.01 wt % to about 10 wt % of dispersed resin beads.
    Type: Application
    Filed: December 21, 2009
    Publication date: October 4, 2012
    Inventors: Sundar Vasudevan, Qin Liu, James P. Shields
  • PIGMENT-BASED INKS
    Publication number: 20120105938
    Abstract: A pigment-based ink includes a non-polar carrier fluid and pigment particles suspended in the non-polar carrier fluid. The pigment particles have surface functionalized anionic groups. A combination of an electronic display and an electronic ink is provided, as is a method for modifying the pigment particles.
    Type: Application
    Filed: November 2, 2010
    Publication date: May 3, 2012
    Inventors: Qin Liu, Zhang-Lin Zhou
  • PIGMENT-BASED INK
    Publication number: 20120081778
    Abstract: A pigment-based ink comprises: a non-polar carrier fluid; and pigment particles suspended in the non-polar carrier fluid. The pigment particles are coated with a metal oxide that is modified with at least one silane coupling agent to introduce functional groups, steric stabilizers or both. A combination of an electronic display and an electronic ink is provided, as is a method for modifying the pigment particles.
    Type: Application
    Filed: October 5, 2010
    Publication date: April 5, 2012
    Inventors: Qin Liu, Zhang-Lin Zhou, Tim R. Koch
  • Diacylglycerol acyltransferases from flax
    Patent number: 8148602
    Abstract: The invention relates to isolated diacylglycerol acyltransferases and polynucleotide sequences encoding the DGAT enzymes; polynucleotide constructs, vectors and host cells incorporating the polynucleotide sequences; and methods of producing and using same. Also provided are transformed cells and transgenic plants, especially Camelina sativa plant, with enhanced oil accumulation and quality.
    Type: Grant
    Filed: March 9, 2009
    Date of Patent: April 3, 2012
    Inventors: Randall Weselake, Rodrigo Siloto, Qin Liu, André Laroche, Eric Murphy, Kimmo Koivu
  • METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PRURITIS
    Publication number: 20120073001
    Abstract: The invention features therapeutic compositions comprising agents useful for the treatment or prevention of pruritis, and methods useful for identifying such agents.
    Type: Application
    Filed: November 30, 2009
    Publication date: March 22, 2012
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Xinzhong Dong, Qin Liu, David J. Anderson