Abstract: Various embodiments a method and apparatus for unmanned driving behavior decision-making and model training, and an electronic device. The method includes: acquiring sample data, wherein the sample data includes a sample image; extracting a sample feature vector corresponding to the sample data, wherein a feature vector of the sample image is extracted by manifold dimension reduction; and based on the sample feature vector, training by semi-supervised learning to obtain a target decision-making model, wherein the target decision-making model is used for decision-making classification.

Abstract: Disclosed are an abietane type diterpene compound, a preparation method and an application thereof, relating to the technical field of anti-tumor compounds, where the compound has a chemical structure as shown in the following formula I: Leucosceptrum canum is extracted to prepare the abietane type diterpene compound according to the present application, and the prepared compound is effectively applied in inhibiting human lung cancer cell A549 and human myeloid leukemia cell HL-60.

Abstract: Disclosed are an abietane type diterpene compound, a preparation method and an application thereof, relating to the technical field of anti-tumor compounds, where the compound has a chemical structure as shown in the following formula I: Leucosceptrum canum is extracted to prepare the abietane type diterpene compound according to the present application, and the prepared compound is effectively applied in inhibiting human lung cancer cell A549 and human myeloid leukemia cell HL-60.

Abstract: The disclosure provides compositions and methods for the Vectored Augmentation of the Destruction, Expression and/or Regulation of proteins, e.g., VA-DER systems and methods.

Abstract: The disclosure provides compositions and methods for the preparation, manufacture and therapeutic use of viral vectors, such as adeno-associated virus (AAV) particles having viral genomes encoding one or more antibodies or antibody fragments or antibody-like polypeptides, for the prevention and/or treatment of diseases and/or disorders.

Abstract: The disclosure provides a packaging structure and method of an acoustic device, relating the technical field of semiconductors, including: a substrate and a piezoelectric stack structure located on the substrate, a first organic material layer is disposed on the piezoelectric stack structure, a second organic material layer is disposed on the first organic material layer, the first organic material layer includes a first supporting part and a second supporting part, the second supporting part forms a first acoustic reflection structure, when being transmitted to the first acoustic reflection structure, acoustic waves can be reflected back to the effective area, so that the loss of the acoustic waves is reduced, and the performance of the acoustic device is improved.

Abstract: The disclosure provides a packaging structure and method of an acoustic device, relating the technical field of semiconductors, including: a substrate and a piezoelectric stack structure located on the substrate, a first organic material layer is disposed on the piezoelectric stack structure, a second organic material layer is disposed on the first organic material layer, the first organic material layer includes a first supporting part and a second supporting part, the second supporting part forms a first acoustic reflection structure, when being transmitted to the first acoustic reflection structure, acoustic waves can be reflected back to the effective area, so that the loss of the acoustic waves is reduced, and the performance of the acoustic device is improved.

Abstract: Disclosed is an in-situ vacuum reaction system for dynamically detecting defects, which includes an electron paramagnetic resonance spectrometer, an in-situ vacuum reaction chamber, a gas supply unit, a vacuum unit, an illumination unit, a temperature control unit and a mixing bottle, the in-situ vacuum reaction chamber is arranged inside a detection cavity of the electron paramagnetic resonance spectrometer, the gas supply unit is connected to the mixing bottle through a pipeline, and the mixing bottle is connected to a gas inlet of the in-situ vacuum reaction chamber through a pipeline, the vacuum unit is connected to the gas inlet of the in-situ vacuum reaction chamber through a pipeline, the illumination unit is arranged corresponding to a detachable window of the electron paramagnetic resonance spectrometer, and the temperature control unit is connected to the electron paramagnetic resonance spectrometer through a pipeline.

Abstract: The disclosure provides compositions and methods for the preparation, manufacture and therapeutic use of viral vectors, such as adeno-associated virus (AAV) particles having viral genomes encoding one or more antibodies or antibody fragments or antibody-like polypeptides, for the prevention and/or treatment of diseases and/or disorders.

Abstract: The present invention relates to adeno-associated viral (AAV) particles modulatory polynucleotides encoding at least one siRNA molecules and methods of use thereof.

Abstract: The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts for enhanced tropism to a target tissue.

Abstract: Compositions and methods relating to potentially pathogenic mutations in the nucleotide sequence of a human LIPA gene. Some LIPA gene products have been discovered to be associated with reduced lysosomal acid lipase (LAL) activity.

Abstract: The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts for enhanced tropism to a target tissue.

Abstract: The present invention relates to adeno-associated viral (AAV) particles modulatory polynucleotides encoding at least one siRNA molecules and methods of use thereof.

Abstract: Compositions and methods relating to potentially pathogenic mutations in the nucleotide sequence of a human LIPA gene. Some LIPA gene products have been discovered to be associated with reduced lysosomal acid lipase (LAL) activity.

Abstract: A method for subscription service in an IP multimedia subsystem is disclosed. A Session Border Controller (SBC) establishes IP channels between the SBC and an IMS terminal as well as between the SBC and a Resource List Server (RLS) after receiving a status subscribe request message from the IMS terminal; and the RLS sends the status information and an acknowledgment message to the IMS terminal through the IP channels after finding subscribed status information for the IMS terminal. A system for a subscription service in an IP multimedia subsystem network is further disclosed. The IP channels established in the present disclosure to transmit the subscription information on the RLS not only can transmit a great amount of information, but also has higher efficiency of information transmission, as long as the IMS terminal has a capability of processing IP data packets.

Abstract: A method for subscription service in an IP multimedia subsystem is disclosed. A Session Border Controller (SBC) establishes IP channels between the SBC and an IMS terminal as well as between the SBC and a Resource List Server (RLS) after receiving a status subscribe request message from the IMS terminal; and the RLS sends the status information and an acknowledgment message to the IMS terminal through the IP channels after finding subscribed status information for the IMS terminal. A system for a subscription service in an IP multimedia subsystem network is further disclosed. The IP channels established in the present disclosure to transmit the subscription information on the RLS not only can transmit a great amount of information, but also has higher efficiency of information transmission, as long as the IMS terminal has a capability of processing IP data packets.

Abstract: A system for recanalizing an occluded blood vessel including a centering catheter employed to center an ablative guide wire within the blood vessel as the guide wire traverses the occlusion. The centering catheter includes a catheter body with an operative lumen through which the ablative guide wire is slidingly disposed. The centering catheter further includes a distally disposed centering mechanism that, when activated, centers the ablative guide wire within the blood vessel as it traverses the occlusion. The centering mechanism can comprise various embodiments including a single inflatable balloon or segmented inflatable balloon, which is in fluid communication with an inflation lumen. An airless preparation lumen may be disposed within the inflation lumen for ease of centering catheter preparation. The ablative guide wire includes insulation that is preferably formed of heat shrink tubing, which is stretched prior or concurrently with the heating process.

Abstract: A stent delivery system which includes a catheter having a radially expandable stent coaxially arranged near a distal end of the catheter. The catheter is equipped with at least one stent securement hub disposed about a portion of the distal end of the catheter underlying the stent. Each of the at least one stent securement hubs being made of a radiopaque polymer.

Abstract: A system for recanalizing an occluded blood vessel including a centering catheter employed to center an ablative guide wire within the blood vessel as the guide wire traverses the occlusion. The centering catheter includes a catheter body with an operative lumen through which the ablative guide wire is slidingly disposed. The centering catheter further includes a distally disposed centering mechanism that, when activated, centers the ablative guide wire within the blood vessel as it traverses the occlusion. The centering mechanism can comprise various embodiments including a single inflatable balloon or segmented inflatable balloon, which is in fluid communication with an inflation lumen. An airless preparation lumen may be disposed within the inflation lumen for ease of centering catheter preparation. The ablative guide wire includes insulation that is preferably formed of heat shrink tubing, which is stretched prior or concurrently with the heating process.