Abstract: The invention provides methods for making porous devices from substantially monodisperse populations of substantially spherical particles of polyarylketone polymers or of thio-analogues of such polymers, of selected sizes. The porous devices allow greater control of porosity than previously available porous devices. In some embodiments, the porous devices are frits, filters, membranes or monoliths.

Abstract: A heat dissipation assembly and a communication module. The heat dissipation assembly includes a housing and a heat generation device disposed inside the housing, wherein the housing is provided therein with a heat insulation cavity around the periphery of the heat generation device, the heat insulation cavity is provided with a through hole, and the housing is provided therein with a heat conduction assembly disposed through the through hole and configured to conduct the heat of the heat generation device to the housing.

Abstract: A filter includes an inlet side, an outlet side, and a body. The body includes a first substrate that includes an array of inlet holes passing through the first substrate, and a second substrate that includes an array of outlet holes passing through the second substrate. The body further includes an intermediate region that includes a plurality of channels extending along a plane that is transverse or at an angle to a main axis of the filter. Each channel communicates directly or indirectly with at least one of the inlet holes and at least one of the outlet holes. The filter provides a plurality of fluid flow paths through the body from the inlet side to the outlet side.

Abstract: A filter includes an inlet side, an outlet side, and a body. The body includes a first substrate that includes an array of inlet holes passing through the first substrate, and a second substrate that includes an array of outlet holes passing through the second substrate. The body further includes an intermediate region that includes a plurality of channels extending along a plane that is transverse or at an angle to a main axis of the filter. Each channel communicates directly or indirectly with at least one of the inlet holes and at least one of the outlet holes. The filter provides a plurality of fluid flow paths through the body from the inlet side to the outlet side.

Abstract: Provided herein are pyranonaphthoquinone compounds and methods of using pyranonaphthoquinone compounds. The method of using the pyranonaphthoquinone compounds includes selectively inhibiting 4E-BP1 phosphorylation by administering at least one pyranonaphthoquinone or pyranonaphthoquinone analog to a subject in need thereof.

Abstract: A micro-machined frit is provided for use in a chromatography column, having a substrate with a thickness, and holes extending through the thickness and providing fluid communication through the substrate. A micro-machined flow distributor is provided for use in a chromatography column having a substrate, holes extending through the substrate, and channels in fluid communication with the holes. A micro-machined integrated frit and flow distributor device is also provided having a substrate with a thickness, holes extending through the thickness and providing fluid communication therethrough, and channels in fluid communication with at least one of the holes. A chromatography column is provided having a tube, an extraction medium contained therein, and a micro-machined frit positioned proximate an end of the tube. The column can include a micro-machined flow distributor positioned between the frit and the end of the tube.

Abstract: A networking operation dispatch system based on electronic zones for rail vehicle comprises: a zone-end relay computer, a communication ranging antenna along rail, a locomotive-mounted response computer and a road networking computer, wherein: the zone-end relay computer is installed on an end of each electronic zone; the communication ranging antenna along rail has an equivalent length to the electronic zone, a first end of the communication ranging antenna along rail is connected with the zone-end relay computer and a second thereof is disposed in the air; the locomotive-mounted response computer is installed on each locomotive and communicates with the zone-end relay computer in the electronic zone occupied by the locomotive via the communication ranging antenna; and the road networking computer connects each zone-end relay computer to form a network. A rail security detecting sensor is provided in the electronic zone.

Abstract: A networking operation dispatch system based on electronic zones for rail vehicle comprises: a zone-end relay computer, a communication ranging antenna along rail, a locomotive-mounted response computer and a road networking computer, wherein: the zone-end relay computer is installed on an end of each electronic zone; the communication ranging antenna along rail has an equivalent length to the electronic zone, a first end of the communication ranging antenna along rail is connected with the zone-end relay computer and a second thereof is disposed in the air; the locomotive-mounted response computer is installed on each locomotive and communicates with the zone-end relay computer in the electronic zone occupied by the locomotive via the communication ranging antenna; and the road networking computer connects each zone-end relay computer to form a network. A rail security detecting sensor is provided in the electronic zone.

Abstract: The present invention provides a method for improving operation density of rail vehicles and for preventing head-on collision and rear-ending collision. Said method divides a rail line into equidistant electronic zones, the length of a zone being greater than the shortest safe distance between two running vehicles. Said method installs a locomotive passing detection alarm device in each zone, when a locomotive travels at high speed on the rail, the locomotive passing detection alarm device corresponding to the zone occupied by the locomotive itself will simultaneously access adjacent front and back zones, and determine whether the two adjacent zones are simultaneously occupied by locomotives. If the two adjacent. zones are simultaneously occupied by locomotives, the locomotive passing alarm device will send an alarm signal to the locomotives to warn or otherwise take measures.

Abstract: The present invention provides a method for improving operation density of rail vehicles and for preventing head-on collision and rear-ending collision. Said method divides a rail line into equidistant electronic zones, the length of a zone being greater than the shortest safe distance between two running vehicles. Said method installs a locomotive passing detection alarm device in each zone, when a locomotive travels at high speed on the rail, the locomotive passing detection alarm device corresponding to the zone occupied by the locomotive itself will simultaneously access adjacent front and back zones, and determine whether the two adjacent zones are simultaneously occupied by locomotives. If the two adjacent. zones are simultaneously occupied by locomotives, the locomotive passing alarm device will send an alarm signal to the locomotives to warn or otherwise take measures.

Abstract: A micro-machined frit is provided for use in a chromatography column, having a substrate with a thickness, and holes extending through the thickness and providing fluid communication through the substrate. A micro-machined flow distributor is provided for use in a chromatography column having a substrate, holes extending through the substrate, and channels in fluid communication with the holes. A micro-machined integrated frit and flow distributor device is also provided having a substrate with a thickness, holes extending through the thickness and providing fluid communication therethrough, and channels in fluid communication with at least one of the holes. A chromatography column is provided having a tube, an extraction medium contained therein, and a micro-machined frit positioned proximate an end of the tube. The column can include a micro-machined flow distributor positioned between the frit and the end of the tube.

Abstract: A microfabricated device has a first substrate, a second substrate, a film bulk acoustic resonator (FBAR) device, and a circuit. The second substrate is bonded to the first substrate to define a chamber. The FBAR device is located on a surface of the first substrate and inside the chamber. The circuit is located on a surface of the second substrate and inside the chamber. An electrical connection connects the circuit and the FBAR device.

Abstract: An attachment system. The attachment system includes a first structure and a second structure. The first structure has a surface and a recess in the surface. The second structure is molded into the recess and extends above the surface. The second structure adheres to the first structure at a boundary of the recess.

Abstract: A device comprises a first substrate, a second substrate and a compliant element. The compliant element is composed of a first, compliant material between the first substrate and the second substrate and has a side surface coated at least in part with a layer of a second material. The compliant element exhibits deformation consistent with the first substrate and a second side having been pressed together. In some embodiments, the second material is electrically conductive such that the compliant element provides a reliable electrical connection between the substrates. In other embodiments, the second material increases the hermeticity of the compliant element such that the compliant element provides a better hermetic seal between the substrates.

Abstract: Apparatus, packaging, and methods of manufacture of an integrated circuit are provided. The integrated circuit includes a component of a first type fabricated on a first substrate containing a first material, and a component of a second type fabricated on a second substrate containing a second material. The first material has better compatibility than the second material with fabrication and/or performance of the component of the first type, while the second material has better compatibility than the first material with fabrication and/or performance of the component of the second type. Also described, is a method of making the above-mentioned integrated circuit, the method including, among other steps, the step of disposing the first and second substrates opposite one another, and the step of establishing an electrical connection between the components.

Abstract: Methods for fragmenting and labeling DNA in a single reaction volume and incubation step using a uracil DNA glycosylase, an apurinic/apyrimidinic endonuclease, and a terminal transferase are disclosed. In a preferred embodiment the UDG, AP and TdT activities are first mixed together to form an enzyme mixture and then the enzyme mixture is mixed with the uracil containing DNA. The fragmentation and labeling reactions thus take place simultaneously as part of the same reaction. The methods may be used in a variety of applications where fragmenting and end-labeling single or double stranded DNA is desired.

Abstract: An attachment system. The attachment system includes a first structure and a second structure. The first structure has a surface and a recess in the surface. The second structure is molded into the recess and extends above the surface. The second structure adheres to the first structure at a boundary of the recess.

Abstract: Apparatus, packaging, and methods of manufacture of an integrated circuit are provided. The integrated circuit includes a component of a first type fabricated on a first substrate containing a first material, and a component of a second type fabricated on a second substrate containing a second material. The first material has better compatibility than the second material with fabrication and/or performance of the component of the first type, while the second material has better compatibility than the first material with fabrication and/or performance of the component of the second type. Also described, is a method of making the above-mentioned integrated circuit, the method including, among other steps, the step of disposing the first and second substrates opposite one another, and the step of establishing an electrical connection between the components.

Abstract: A microfabricated device has a first substrate, a second substrate, a film bulk acoustic resonator (FBAR) device, and a circuit. The second substrate is bonded to the first substrate to define a chamber. The FBAR device is located on a surface of the first substrate and inside the chamber. The circuit is located on a surface of the second substrate and inside the chamber. An electrical connection connects the circuit and the FBAR device.

Abstract: A device includes first and second supports, a rotatable body and first and second flexible members. The first flexible member extends between the first support and a first position on the rotatable body. The second flexible member extends between the second support and a second position on the rotatable body. At least one of the supports is capable of linear movement in a first direction with respect to the other. The first position is offset from the second position in a second direction orthogonal to the first direction.