Abstract: Application of glutamate dehydrogenase GdhA of Peptostreptococcus asaccharolyticus in increasing the yield of poly-?-glutamic acid from Bacillus licheniformis. The glutamate dehydrogenase GdhA of the Bacillus licheniformis WX-02 per se is replaced with the glutamate dehydrogenase derived from the Peptostreptococcus asaccharolyticus by means of homologous recombination, which significantly increases the level of synthesizing the poly-?-glutamic acid for the Bacillus licheniformis, and the yield of the obtained poly-?-glutamic acid from strains is increased at least by more than 20% compared with control strains.

Abstract: A distributed fiber-optic acoustic sensing system and a signal processing method. The distributed fiber-optic acoustic sensing system is based on a high spatial resolution distributed fiber-optic acoustic sensor. The interval between adjacent sensing units is centimeter or millimeter level. Through specific digital signal processing, signal enhancement can be realized, noise in the system and environment are suppressed, at the same time, problems such as interference fading is solved, and the sensor signal-to-noise ratio of subunits can be increased by two to three orders of magnitude. Each subunit can serve as an independent high-sensitivity sensor for sensing. The multiple subunits can form one or more new sensor arrays. The azimuth estimation and spatial orientation of signal sources can be realized by the array signal processing method.

Abstract: The present invention provides a high-strength and high-heat-resistant bio-based polyamide composition, which consists of the following parts of materials by mass: 43.50-89.95% of bio-based polyamide resin slices; 10-50% of reinforcements; 0.01-2% of rare earth compounds; 0.01-1% of copper salt antioxidant combinations; 0.01-1% of free-radical scavengers; 0.01-0.5% of heat-conducting masterbatches; 0.01-1% of stabilizers; and 0-1% of dispersants. The advantage of the present invention is presented in that: the bio-based polyamide resin slice is prepared through a stepwise polycondensation process of pentanediamine and adipic acid, or through a stepwise polycondensation process of pentanediamine, adipic acid and terephthalic acid and the pentanediamine is prepared through fermentation of starch, so the prepared polyamide resin pertains to an environmentally-friendly engineering plastic.

Abstract: Methods, systems, and devices for access control configurations for inter-processor communications are described to support reconfiguration of a dynamic access control configuration at a device. The configuration may support additional configuration fields that may be added to existing access control rules of the device. A processor of the device may request creation of a new shared memory resource, using a subregion of an existing memory resource, where the additional fields may indicate a parent memory resource for the new memory resource. The additional fields may also include a value which may indicate a processor which has write permission for a respective memory region of the shared memory, where other processors of the device may be prevented from writing to the memory region. The additional fields may further indicate a chain of delegation, or a history, of which processors have been assigned the exclusive write permission for the respective memory region.

Abstract: A first device is logged in with a first user account. The first device displays an avatar of a second user account in a first user interface of the first device. In response to an interaction instruction triggered on the avatar of the second user account, the first device generates an interaction message according to a first field corresponding to the first user account, an action description field corresponding to the interaction instruction, and a second field corresponding to the second user account. The first device transmits the interaction message to a second device that is logged in with the second user account.

Abstract: This application provides a method for issuing a digital certificate performed by a digital certificate issuing center that includes a public-private key generation module and an authentication module. The method includes: receiving a public-private key request from a node in a blockchain network; generating a public key and a private key of the node by using the public-private key generation module, and transmitting the public and private keys to the node; receiving the public key of the node and registration information of the node, and authenticating the registration information by using the authentication module; and generating, in accordance with a determination that the authentication succeeds, a digital certificate of the node by using the authentication module, and transmitting the digital certificate to the node. The embodiments of this application can improve the probative value of an issued digital certificate, thereby improving the security of data exchange in a blockchain network.

Abstract: A combined bio-artificial liver support system, includes branch tubes that are connected in sequence: a blood input branch tube, an upstream tail end, a first plasma separation branch tube comprising at least a first plasma separator, a non-biological purification branch tube comprising at least a plasma perfusion device and a bilirubin adsorber, a biological purification branch tube comprising at least a hepatocyte culture cartridge assembly, and a plasma return branch tube, a downstream tail end of which is set as a blood output end.

Abstract: A method for multi-stage programming of a non-volatile memory structure, wherein the method comprises: (1) initiating a programming operation with respect to a memory block, (2) applying a programming algorithm to the memory block, wherein the programming algorithm comprises at least a first programming stage and a second programming stage, and (3) between the first programming stage and the second programming stage, applying a time delay according to a pre-determined amount of time. Further, the pre-determined amount of time may be defined as the amount of time that, according to a probabilistic function, permits de-trapping of any charges unintentionally trapped within a memory cell of the memory block as a result of the first programming stage.

Abstract: A display panel and a display device are disclosed. The display panel includes a first substrate and a second substrate that are aligned and bonded together, and further includes a spacer disposed between the first substrate and second substrate. One end of the spacer is disposed on the second substrate, and the other end faces the first substrate. The first substrate further includes a first limiting groove that is disposed on one side adjacent to the second substrate and that corresponds to a position of the spacer. The other end of the spacer extends into the first limiting groove. A first limiting protruding strip is disposed on a groove wall of the first limiting groove, and the surface of the first limiting protruding strip facing the spacer abuts against the side wall of the spacer, defining a gap between the spacer and the groove wall of the first limiting groove.

Abstract: Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) agonists and methods of their use to treat diseases involving IGFBP-3 and IGFBP-3R are provided. The agonists may be antibodies or other molecules specific for binding to and activating IGFBP-3R. The agonists are used to treat e.g. cancer, metabolic syndrome and obstructive respiratory disorders. In addition, methods of diagnosing cancer and predicting the chance of recurrence, metastasis and/or survival by measuring the level of IGFBP-3R in tumor tissue are provided.

Abstract: A display panel and a display device are disclosed. The display panel includes a first substrate and a second substrate that are aligned and bonded together, and further includes a spacer disposed between the first substrate and second substrate. One end of the spacer is disposed on the second substrate, and the other end faces the first substrate. The first substrate further includes a first limiting groove that is disposed on one side adjacent to the second substrate and that corresponds to a position of the spacer. The other end of the spacer extends into the first limiting groove. A first limiting protruding strip is disposed on a groove wall of the first limiting groove, and the surface of the first limiting protruding strip facing the spacer abuts against the side wall of the spacer, defining a gap between the spacer and the groove wall of the first limiting groove.

Abstract: The present disclosure provides a diffusive gradients in thin films (DGT) probe test device for a sediment core in a lake, including: a sampling tube, where, a settlement limit device is disposed on an outer wall of the sampling tube and a DGT probe and a multi-parameter water-quality detection electrode are installed within the sampling tube; a movable mudguard device comprising a connecting rod and a mudguard, where, the connecting rod rotates around a rotating shaft to drive the mudguard to move from a position where an opening at the lower end of the sampling tube is sealed to a side of the sampling tube; a position-limit mechanism removably installed outside the sampling tube; a hammering device located above the sampling tube and fixedly connected to the sampling tube; and a floating ball located above the hammering device and connected to the hammering device via a first pull rope.

Abstract: A battery exchange method is implemented in a control device communicatively coupled to a work machine and a battery exchange device. The method includes receiving a battery exchange request from the work machine, calculating a synchronization location and a synchronization time of the work machine and the battery exchange device, generating pre-judgment information, sending the pre judgment information and a synchronization command to the battery exchange device to control the battery exchange device to move toward the work machine according to the pre-judgment information and the synchronization command, continually receiving the first status information from the work machine and second status information from the battery exchange device, determining whether synchronization of the work machine and the battery exchange device is complete, and sending a battery exchange command to the battery exchange device to control the battery exchange device to exchange the battery of the work machine.

Abstract: The invention relates to the technical field of test equipment, in particular to a test device for simulating pollutant migration and transformation in icing and melting processes of a water body. The device comprises: a transparent cylinder body with the top open and the bottom closed, used for holding a test water body; a transparent box body, wherein the top of the box body is provided with a through hole through which the cylinder body is provided in the box body; a first refrigerating system including a first evaporator provided in the cylinder body close to an opening of the cylinder body, wherein the first refrigerating system is used for controlling the temperature of a first space from a surface of a test water body in the cylinder body to the opening of the cylinder body through the first evaporator; and a second refrigerating system used for controlling the temperature in the box body.

Abstract: Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) agonists and methods of their use to treat diseases involving IGFBP-3 and IGFBP-3R are provided. The agonists may be antibodies or other molecules specific for binding to and activating IGFBP-3R. The agonists are used to treat e.g. cancer, metabolic syndrome and obstructive respiratory disorders. In addition, methods of diagnosing cancer and predicting the chance of recurrence, metastasis and/or survival by measuring the level of IGFBP-3R in tumor tissue are provided.

Abstract: The present invention relates to a method for writing data comprising a sequence of bits, the data being written in a form of nucleic acid, by in-vitro enzymatically producing memory nucleic acid from a strand of memory writing substrate nucleic acid, wherein the strand of memory writing substrate nucleic acid comprises a plurality of spacer sections and memory writing sections sandwiched between the spacer sections. Each of the spacer sections comprises one or more nucleobases, and each of the memory writing sections comprises a nucleobase other than the nucleobases of an adjacent spacer section upstream of the memory writing section in a travel direction of an enzyme along the strand of memory writing substrate nucleic acid.

Abstract: A method for writing data including a sequence of bits, the data being written in a form of DNA, by in-vitro enzymatically producing memory DNA from a strand of memory writing substrate DNA is disclosed. In one aspect, the method includes repeating of: receiving a sub-sequence of the sequence of bits, the sub-sequence including at least one bit; selecting memory nucleotides based on the sub-sequence; contacting, in liquid medium including the strand of memory writing substrate DNA contacted with an enzyme, the selected memory nucleotides and the enzyme; and synthesizing a portion of the memory DNA from a portion of the strand of memory writing substrate DNA by the enzyme and at least one of the memory nucleotides of the solution, thereby producing memory DNA including memory nucleotides corresponding to bits of the sequence of bits. The disclosed technology further relates to a micro-fluidic system including a microfluidic chip and a controller.

Abstract: Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) agonists and methods of their use to treat diseases involving IGFBP-3 and IGFBP-3R are provided. The agonists may be antibodies or other molecules specific for binding to and activating IGFBP-3R. The agonists are used to treat e.g. cancer, metabolic syndrome and obstructive respiratory disorders. In addition, methods of diagnosing cancer and predicting the chance of recurrence, metastasis and/or survival by measuring the level of IGFBP-3R in tumor tissue are provided.

Abstract: The invention relates to the technical field of test equipment, in particular to a test device for simulating pollutant migration and transformation in icing and melting processes of a water body. The device comprises: a transparent cylinder body with the top open and the bottom closed, used for holding a test water body; a transparent box body, wherein the top of the box body is provided with a through hole through which the cylinder body is provided in the box body; a first refrigerating system including a first evaporator provided in the cylinder body close to an opening of the cylinder body, wherein the first refrigerating system is used for controlling the temperature of a first space from a surface of a test water body in the cylinder body to the opening of the cylinder body through the first evaporator; and a second refrigerating system used for controlling the temperature in the box body.

Abstract: The present disclosure provides a diffusive gradients in thin films (DGT) probe test device for a sediment core in a lake, including: a sampling tube, where, a settlement limit device is disposed on an outer wall of the sampling tube and a DGT probe and a multi-parameter water-quality detection electrode are installed within the sampling tube; a movable mudguard device comprising a connecting rod and a mudguard, where, the connecting rod rotates around a rotating shaft to drive the mudguard to move from a position where an opening at the lower end of the sampling tube is sealed to a side of the sampling tube; a position-limit mechanism removably installed outside the sampling tube; a hammering device located above the sampling tube and fixedly connected to the sampling tube; and a floating ball located above the hammering device and connected to the hammering device via a first pull rope.