Abstract: Provided are an arginine deiminase mutant, a covalent dimer and a conjugate and a use thereof. The provided arginine deiminase mutant forms a covalent disulfide bond between arginine deiminase subunits by means of mutation of an amino acid site on arginine deiminase. Also provided are a covalent conjugate and a use in the field of cancer treatment. Site-directed mutagenesis of an amino acid site promotes formation of a covalent disulfide bond between non-covalent homodimeric arginine deiminase subunits, and a formed dimer has a more stable structure; in addition, the exposure level of an epitope on an interaction interface can be reduced, the in vivo immunogenicity is reduced, and a more excellent anti-tumor effect is exhibited.

Abstract: A monitoring module includes a pressurization component and a thin-film sensor. The pressurization component is configured to apply pressure to a measured part. The thin-film sensor is configured to measure a pulse wave signal at the measured part, and the thin-film sensor is disposed between the pressurization component and the measured part.

Abstract: Provided are an organic compound and an application thereof. The organic compound has a structure as shown in Formula I. The overlap degree between HOMO and LUMO is effectively reduced through structural framework design and specific group introduction, thus the energy level difference between the triplet state and the singlet state is reduced to below 300 meV, the reverse crossing of the energy from the triplet to the singlet is satisfied. The organic compound obtains a relatively balanced radiative transition rate and good TADF characteristics, and has excellent carrier transport performance, balance and stability of electron mobility and hole mobility, low preparation cost, and environmental friendliness. The organic compound can be used as a light-emitting layer material of an OLED device, and the material has a TADF light-emitting mechanism and high light-emitting quantum efficiency, which can reduce the drive voltage and energy consumption, and improve luminous efficiency and working life.

Abstract: A method of making a free-standing nanoporous Zn is provided. The method includes compacting a predetermined amount of Zn compound precursor into a form of an anode; controlling a thickness of the Zn compound precursor to obtain desirable porosity; and reducing the Zn compound precursor in an electrochemical cell having an electrolyte at a predetermined volage against a reference electrode to obtain a nanoporous Zn anode. The nanoporous Zn includes continuous metal ligaments and pores each having a uniform width of around a few hundred nanometers. The nanoporous Zn may serve as an anode in a rechargeable Zn battery having the nanoporous Zn anode coupled to a conductive substrate, a physical block, an electrolyte, a reference electrode, and a cathode electrode, to deliver a high areal capacity and a long cycle life.

Abstract: A self-locking power plug includes an insulating seat, conductors, a locking plate, a slider, and an elastic element. The insulating seat includes a mating surface and defines an insertion direction toward the mating surface. A track is provided in the insulating seat parallel to the insertion direction, and first, second, and third channels exposing the conductors and opening onto the mating surface are formed within the insulating seat. The locking plate is placed inside the insulating seat and transversely extends across a longitudinal direction of the first channel. The slider is movable along the track between a released position and a locked position and drives the locking plate to rotate. The elastic element abuts against the insulating seat and the slider. At the released position, the locking plate is perpendicular to the first channel. At the locked position, the locking plate is inclined relative to the first channel.

Abstract: A self-locking power plug includes: an insulation base having an engage surface and defining an insertion direction, a rail and a first channel, a second channel and a third channel are disposed in the insulation base; plural conductive members mounted in the insulation base and exposed in the aforesaid three channels; a locking sheet disposed in the insulation base and having a penetrated hole, a fixed side and a moveable side; a slide block disposed on the rail and sliding between a locked position and a released position, the slide block hooks the moveable side to drive the locking sheet to rotate; and an elastic unit disposed in the insulation base and abutting against the insulation base and the slide block to make the slide block be preloaded with a force along a direction opposite to the insertion direction and towards the locked position.

Abstract: This application is directed to controlling power consumption of a data interface of an electronic device. The electronic device includes a data port for coupling the electronic device to an external device, a data interface circuit coupled to the data port, and a power controller coupled to the data interface circuit. The data interface circuit is configured to receive a first power signal provided based on an interface power control signal and exchange data with the external device coupled via the data port. The power controller is configured to receive a second power signal distinct from the first power signal, monitor an interface operation state of the data interface circuit, and generate the interface power control signal based on the interface operation state. In some implementations, the power controller includes latches for holding state signals corresponding to the interface operation state, before and while the first power signal is disabled.

Abstract: This application is directed to a data interface having an input interface for receiving a differential input signal and a reference interface for providing a predefined reference voltage. A high pass filter is coupled to the input interface, and configured to filter the differential input signal and generate a filtered differential input signal. A differential integrator is coupled to the high pass filter and reference interface, and configured to receive the filtered differential input signal and generate a differential output signal including a first output signal and a second output signal. Each of the first and second output signals has a common mode output voltage substantially equal to the predefined reference voltage. In some embodiments, the data interface includes a connector including a plurality of data lanes and a pair of command pins that are distinct from the data lanes and coupled to the input interface.

Abstract: An integrated conducting ring and a hair styling appliance are provided. The integrated conducting ring includes a housing, a rotating member, and a wiring assembly. The housing is provided with a middle through hole and multiple mounting holes. The rotating member can be rotatably mounted in the middle through hole, and is provided with multiple annular electrodes and multiple lead wires. The multiple annular electrodes correspond to the multiple mounting holes; and the multiple lead wires are correspondingly connected to the multiple annular electrodes and extend out from a first end of the rotating member. The first end of the rotating member is connected to a driven mechanism, and a second end of the rotating member is connected to a drive mechanism. The wiring assembly includes multiple conducting members, and each conducting member is correspondingly mounted in one mounting hole and abuts against the corresponding annular electrode.

Abstract: Embodiments of this application disclose a detection method and a wearable device. The wearable device may collect physiological data and exercise data of a user in a plurality of periods such as pre-exercise, in-exercise, and post-exercise. An exercise and health result of the user may be obtained based on the physiological data and the exercise data.

Abstract: The embodiment of the disclosure relates to a media generation method, apparatus, device and storage medium. The method provided herein includes: receiving a media generation request of a user; in response to the media generation request, determining a first media content from a media library associated with the user; and presenting a second media content generated based at least on the first media content, the second media content including a first portion and a second portion, the first portion corresponding to picture content of the first media content, and the second portion indicating reference information associated with the first media content.

Abstract: A system and method for power line communication (PLC) reception are provided. In one embodiment, a tractor controller is provided comprising a main processor, a first co-processor, a second co-processor, and third co-processor. The first co-processor is configured to create a digital waveform from an analog power line communication (PLC) message received from a trailer via a power line. The second co-processor is configured to: for each of a plurality of chirps in the digital waveform, compare a given chirp with a previous chirp to predict whether a phase change occurred; and create a digital bit stream representing the PLC message from the predictions. The third co-processor is configured to process the digital bit stream and send the digital bit stream to the main processor. Other embodiments are provided.

Abstract: A airbag assembly includes an expansion airbag layer and a protrusion airbag layer disposed on a surface of the expansion airbag layer, and an air passage for air circulation is disposed between the two airbag layers. The protrusion airbag layer includes a plurality of sub-airbags. The plurality of sub-airbags include a first sub-airbag and a second sub-airbag. The first sub-airbag is disposed at a location closer to a middle part of the expansion airbag layer than the second sub-airbag. A capacity of an inflation cavity of the first sub-airbag is less than a capacity of an inflation cavity of the second sub-airbag.

Abstract: A socket connector includes an insulative body (100), a conductor (200), a ball (300) and a slider (400). The insulative body (100) has a socket (101), a slide channel (102) and a communicating path (103), and the communicating path (103) is connected to one side on the socket (101) and one sided on the slide channel (102). The conductor (200) is arranged in the socket (101), and the communicating path (103) is disposed corresponding to one side of the conductor (200). The ball (300) is disposed in the communicating path (103). The slider (400) is disposed in the slide channel (102), and the slider (400) has a slope (401). The slider (400) is slidable along the slide channel (102) to a locking position to press the ball (300) by the slope (401) so as to push the ball (300) into the socket (101) to abut against the conductor (200).

Abstract: Provided is a characteristic element combination anomaly derivative method of determining occurrence of a deep concealed plate-shaped ore body of a hydrothermal deposit. The method determines the spatial occurrence of the deep concealed ore body of the hydrothermal deposit through four working procedures, including: fine measurement of a metallogenic structure and systematic collection of samples, sample processing and multi-element quantitative analysis, mathematical model construction of characteristic element combination anomaly, and determination of the occurrence (the strike, the dip direction, the dip angle and the pitch direction) of the deep concealed ore body. The method solves the problem of judging the occurrence of the deep concealed ore body by interpreting geochemical anomalies of a primary halo and a secondary halo.

Abstract: A compound represented by formula I, and a racemate, stereoisomer, tautomer, solvate, polymorph, or pharmaceutically acceptable salts thereof are provided. The compound has good prostate tumor cell proliferation inhibitory activity and anti-AR activity. The compound has good in-vivo metabolic properties, has high AUC and Cmax, is good in druggability, and can be used for preventing and/or treating androgen-related disorders. The compound also has a good hair growth promoting effect, and can effectively increase the number of hair follicles and the growth length of hair.

Abstract: An organic compound, having a structure shown in formula (I), is provided. The organic compound includes: where X and Y are each independently selected from substituted carbon, divalent heteroatom or substituted heteroatom with a valence greater than 2; A and R are each independently selected from hydrogen, deuterium, substituted or unsubstituted C1-C10 alkyl, substituted or unsubstituted C6-C30 aryl, or substituted or unsubstituted C2-C30 heterocyclic; and when one of A and R is hydrogen or deuterium, another of A and R is not hydrogen or deuterium; and substituents of the substituted carbon, the substituted heteroatom with the valence greater than 2, the substituted C1-C10 alkyl, the substituted C6-C30 aryl and the substituted C2-C30 heterocyclic are each independently selected from one or a combination of deuterium, nitro, cyano, substituted or unsubstituted C1˜C10 alkyl, substituted or unsubstituted C6˜C30 aryl, or substituted and unsubstituted C2˜C30 heterocyclic.

Abstract: Described herein are compounds useful as sweet flavor modifiers. Ingestible compositions that include one or more of these compounds in combination with a natural or artificial sweetener are also described.

Abstract: A smartwatch includes a watch body, an airbag, and a sensor. The watch body is electrically coupled to the sensor. The sensor is disposed on an inner wall of the airbag. When the smartwatch is worn on a wrist of the user, the airbag and the sensor cover the radial artery of the wrist. The sensor is configured to measure the plurality of pulse waves of the radial artery when the airbag is under different pressure strength. The watch body is configured to determine the blood pressure of the user based on the plurality of pulse waves.