Patents by Inventor Qing-Fen Gan

Qing-Fen Gan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS
    Publication number: 20180153830
    Abstract: Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.
    Type: Application
    Filed: February 1, 2018
    Publication date: June 7, 2018
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Hoffmann-La Roche Inc.
    Inventors: Uri BEN-DAVID, Nissim BENVENISTY, Payal ARORA, Qing-Fen GAN, Ralph J. GARIPPA
  • SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS
    Publication number: 20170027890
    Abstract: Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.
    Type: Application
    Filed: September 8, 2016
    Publication date: February 2, 2017
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Hoffmann-La Roche Inc.
    Inventors: Uri BEN-DAVID, Nissim BENVENISTY, Payal ARORA, Qing-Fen GAN, Ralph J. GARIPPA
  • Selective inhibitors of undifferentiated cells
    Patent number: 9456998
    Abstract: Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: October 4, 2016
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Hoffmann-La Roche Inc.
    Inventors: Uri Ben-David, Nissim Benvenisty, Payal Arora, Qing-Fen Gan, Ralph J. Garippa
  • SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS
    Publication number: 20150148359
    Abstract: Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.
    Type: Application
    Filed: May 22, 2013
    Publication date: May 28, 2015
    Inventors: Uri Ben-David, Nissim Benvenisty, Payal Arora, Qing-Fen Gan, Ralph J. Garippa
  • Assays for measuring phosphate modification enzyme activity
    Patent number: 7901901
    Abstract: The present invention relates to assays that can measure the activity of enzymes that catalyze phosphate modifications, such as kinases, phosphatases, cyclases and phosphodiesterases. The assays can also be used to identify and screen for substances that modulate the activity of kinases, phosphatases, cyclases and phosphodiesterases.
    Type: Grant
    Filed: December 9, 2009
    Date of Patent: March 8, 2011
    Assignee: Roche Palo Alto LLC
    Inventor: Qing-Fen Gan
  • Scintillation proximity assay for measuring polymerase activity
    Patent number: 7851156
    Abstract: The present invention provides for methods of assaying the activity of a polymerase enzyme by using a Scintillation Proximity Assay (SPA) without the need of primers modified with affinity tags. The methods of the present invention can be practiced with any number of RNA and DNA polymerase enzymes.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: December 14, 2010
    Assignee: Roche Palo Alto LLC
    Inventor: Qing-Fen Gan
  • ASSAYS FOR MEASURING PHOSPHATE MODIFICATION ENZYME ACTIVITY
    Publication number: 20100086952
    Abstract: The present invention relates to assays that can measure the activity of enzymes that catalyze phosphate modifications, such as kinases, phosphatases, cyclases and phosphodiesterases. The assays can also be used to identify and screen for substances that modulate the activity of kinases, phosphatases, cyclases and phosphodiesterases.
    Type: Application
    Filed: December 9, 2009
    Publication date: April 8, 2010
    Inventor: Qing-Fen Gan
  • Assays for measuring phosphate modification enzyme activity
    Patent number: 7674600
    Abstract: The present invention relates to assays that can measure the activity of enzymes that catalyze phosphate modifications, such as kinases, phosphatases, cyclases and phosphodiesterases. The assays can also be used to identify and screen for substances that modulate the activity of kinases, phosphatases, cyclases and phosphodiesterases.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: March 9, 2010
    Assignee: Roche Palo Alto LLC
    Inventor: Qing-Fen Gan
  • Assays for measuring phosphate modification enzyme activity
    Publication number: 20080145880
    Abstract: The present invention relates to assays that can measure the activity of enzymes that catalyze phosphate modifications, such as kinases, phosphatases, cyclases and phosphodiesterases. The assays can also be used to identify and screen for substances that modulate the activity of kinases, phosphatases, cyclases and phosphodiesterases.
    Type: Application
    Filed: December 13, 2007
    Publication date: June 19, 2008
    Inventor: Qing-Fen Gan
  • Scintillation proximity assay for measuring polymerase activity
    Publication number: 20070134707
    Abstract: The present invention provides for methods of assaying the activity of a polymerase enzyme by using a Scintillation Proximity Assay (SPA) without the need of primers modified with affinity tags. The methods of the present invention can be practiced with any number of RNA and DNA polymerase enzymes.
    Type: Application
    Filed: December 8, 2006
    Publication date: June 14, 2007
    Inventor: Qing-Fen Gan