Patents by Inventor Qing Hong Zhao

Qing Hong Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040107006
    Abstract: A non-crosslinked, decellularized and purified mammalian tissue (e.g., bovine pericardium) having particular use as an implantable resorbable material. The material is treated by alkylating its primary amine groups in a manner sufficient to reduce the antigenicity of the tissue, permitting the treated tissue to be used in vivo and without crosslinking, and in turn, permitting it to be resorbable. The material can be used in surgical repair of soft tissue deficiencies for a certain period of time while the implant itself is gradually remodeled or absorbed by the host. Also provided are a method of preparing such a material, as well as a method of using such a material for surgical repair.
    Type: Application
    Filed: November 24, 2003
    Publication date: June 3, 2004
    Inventors: Ralph T. Francis, Qing Hong Zhao, Amy Desmith, B. Nicholas Oray
  • Patent number: 6652594
    Abstract: A non-crosslinked, decellularized and purified mammalian tissue (e.g., bovine pericardium) having particular use as an implantable resorbable material. The material is treated by alkylating its primary amine groups in a manner sufficient to reduce the antigenicity of the tissue, permitting the treated tissue to be used in vivo and without crosslinking, and in turn, permitting it to be resorbable. The material can be used in surgical repair of soft tissue deficiencies for a certain period of time while the implant itself is gradually remodeled or absorbed by the host. Also provided are a method of preparing such a material, as well as a method of using such a material for surgical repair.
    Type: Grant
    Filed: March 14, 2002
    Date of Patent: November 25, 2003
    Assignee: Synovis Life Technologies, Inc.
    Inventors: Ralph T. Francis, Qing Hong Zhao, Amy DeSmith, B. Nicholas Oray
  • Publication number: 20020138152
    Abstract: A non-crosslinked, decellularized and purified mammalian tissue (e.g., bovine pericardium) having particular use as an implantable resorbable material. The material is treated by alkylating its primary amine groups in a manner sufficient to reduce the antigenicity of the tissue, permitting the treated tissue to be used in vivo and without crosslinking, and in turn, permitting it to be resorbable. The material can be used in surgical repair of soft tissue deficiencies for a certain period of time while the implant itself is gradually remodeled or absorbed by the host. Also provided are a method of preparing such a material, as well as a method of using such a material for surgical repair.
    Type: Application
    Filed: March 14, 2002
    Publication date: September 26, 2002
    Inventors: Ralph T. Francis, Qing Hong Zhao, Amy DeSmith, B. Nicholas Oray
  • Publication number: 20020123789
    Abstract: A stent cover useful as a barrier between an expandable stent and the vascular surface. The cover provides an optimal combination of such properties as thickness, physical characteristics and biocompatability. The cover can be formed to and positioned upon the size and shape of the unexpanded stent, and to then be expanded in situ upon expansion of the stent itself. The cover is prepared from natural tissues such as umbilical arteries, bovine pericardium, and porcine peritoneum.
    Type: Application
    Filed: May 31, 2001
    Publication date: September 5, 2002
    Inventors: Ralph T. Francis, Qing Hong Zhao, B. Nicholas Oray, Anne E. Metzger
  • Patent number: 6312474
    Abstract: A non-crosslinked, decellularized and purified mammalian tissue (e.g., bovine pericardium) having particular use as an implantable resorbable material. The material is treated by alkylating its primary amine groups in a manner sufficient to reduce the antigenicity of the tissue, permitting the treated tissue to be used in vivo and without crosslinking, and in turn, permitting it to be resorbable. The material can be used in surgical repair of soft tissue deficiencies for a certain period of time while the implant itself is gradually remodeled or absorbed by the host. Also provided are a method of preparing such a material, as well as a method of using such a material for surgical repair.
    Type: Grant
    Filed: September 15, 1999
    Date of Patent: November 6, 2001
    Assignee: Bio-Vascular, Inc.
    Inventors: Ralph T. Francis, Qing Hong Zhao, Amy Desmith, B. Nicholas Oray