Patents by Inventor QING LOU
QING LOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10930408Abstract: A triboluminescence isotope battery can include a housing defining a chamber, and one or more energy conversion devices. Each energy conversion device can include a holder, a cantilever beam, a triboluminescence component, a first photoelectric conversion component, a radioactive source, a first charge collecting component, a second charge collecting, a first thermoelectric conversion component, and a heat dissipation component.Type: GrantFiled: October 18, 2019Date of Patent: February 23, 2021Assignee: SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINAInventors: Jiaqing He, Yi Zhou, Delong Li, Qing Lou
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Patent number: 10874318Abstract: This disclosure relates to integrated channel integrity detection and to reconstruction of electrophysiological signals. An example system includes a plurality of input channels configured to receive respective electrical signals from a set of electrodes. An amplifier stage includes a plurality of differential amplifiers, each of the differential amplifiers being configured to provide an amplifier output signal based on a difference between a respective pair of the electrical signals. Channel detection logic is configured to provide channel data indicating an acceptability of each of the plurality of input channels based on an analysis of a common mode rejection of the amplifier output signals.Type: GrantFiled: March 6, 2018Date of Patent: December 29, 2020Assignee: CARDIOINSIGHT TECHNOLOGIES, INC.Inventors: Shahabedin Shahdoostfard, Qingguo Zeng, Ping Jia, Brian P. George, Kevin Ponziani, Qing Lou, Daniel Varghai, Jeffrey B. Adair
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Patent number: 10806359Abstract: One or more non-transitory computer-readable media have instructions executable by a processor and programmed to perform a method. The method includes analyzing the electrical data to locate one or more wave front lines over a given time interval. The electrical data represents electrophysiological signals distributed across a cardiac envelope for one or more time intervals. A respective trajectory is determined for each wave end of each wave front line that is located across the cardiac envelope over the given time interval. A set of connected trajectories are identified based on a duration that the trajectories are connected to each other by a respective wave front line during the given time interval. A connectivity association is characterized for the trajectories in the set of connected trajectories.Type: GrantFiled: April 27, 2017Date of Patent: October 20, 2020Assignee: CARDIOINSIGHT TECHNOLOGIES, INC.Inventors: Qingguo Zeng, Qing Lou, Ryan M. Bokan, Ping Jia, Connor S. Edel, Charulatha Ramanathan
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Patent number: 10729345Abstract: For example, one or more non-transitory computer-readable media includes executable instructions to perform a method. The method includes defining a plurality of spatial regions distributed across a geometric surface. At least one wave front that propagates across the geometric surface is detected based on electrical data representing electrophysiological signals for each of a plurality of nodes distributed on the geometric surface over at least one time interval. An indication of conduction velocity of the wave front is determined for at least one spatial region of the plurality of spatial regions during the time interval based on a duration that the wave front resides within the at least one spatial region. Slow conduction activity is identified for the at least one spatial region based on comparing the indication of conduction velocity relative to a threshold. Conduction data is stored in memory to represent each slow conduction event.Type: GrantFiled: May 4, 2018Date of Patent: August 4, 2020Assignee: CARDIOINSIGHT TECHNOLOGIES, INC.Inventors: Qing Lou, Jeffrey B. Adair, Qingguo Zeng, Ping Jia, Ryan Bokan, Connor Edel, Rahsean Ellis, Brian P. George, Raja Ghanem, Timothy G. Laske
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Publication number: 20200163570Abstract: An example method includes analyzing morphology and/or amplitude of each of a plurality of electrophysiological signals across a surface of a patient's body to identify candidate segments of each signal satisfying predetermined conduction pattern criteria. The method also includes determining a conduction timing parameter for each candidate segment in each of the electrophysiological signals.Type: ApplicationFiled: January 28, 2020Publication date: May 28, 2020Inventors: QING LOU, MEREDTH E. STONE, QINGGUO ZENG, JEFFREY B. ADAIR, CONNOR S. EDEL, PING JIA, KEVIN R. PONZIANI, BRIAN P. GEORGE, RYAN M. BOKAN, MATTHEW J. SABO, VLADIMIR A. TUROVSKIY, KETAL C. PATEL, CHARULATHA RAMANATHAN
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Patent number: 10575749Abstract: An example method includes analyzing morphology and/or amplitude of each of a plurality of electrophysiological signals across a surface of a patient's body to identify candidate segments of each signal satisfying predetermined conduction pattern criteria. The method also includes determining a conduction timing parameter for each candidate segment in each of the electrophysiological signals.Type: GrantFiled: April 27, 2017Date of Patent: March 3, 2020Assignee: CARDIOINSIGHT TECHNOLOGIES, INC.Inventors: Qing Lou, Meredith E. Stone, Qingguo Zeng, Jeffrey B. Adair, Connor S. Edel, Ping Jia, Kevin R. Ponziani, Brian P. George, Ryan M. Bokan, Matthew J. Sabo, Vladimir A. Turovskiy, Ketal C. Patel, Charulatha Ramanathan
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Publication number: 20200051707Abstract: A triboluminescence isotope battery can include a housing defining a chamber, and one or more energy conversion devices. Each energy conversion device can include a holder, a cantilever beam, a triboluminescence component, a first photoelectric conversion component, a radioactive source, a first charge collecting component, a second charge collecting, a first thermoelectric conversion component, and a heat dissipation component.Type: ApplicationFiled: October 18, 2019Publication date: February 13, 2020Inventors: Jiaqing HE, Yi ZHOU, Delong LI, Qing LOU
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Publication number: 20190336023Abstract: For example, one or more non-transitory computer-readable media includes executable instructions to perform a method. The method includes defining a plurality of spatial regions distributed across a geometric surface. At least one wave front that propagates across the geometric surface is detected based on electrical data representing electrophysiological signals for each of a plurality of nodes distributed on the geometric surface over at least one time interval. An indication of conduction velocity of the wave front is determined for at least one spatial region of the plurality of spatial regions during the time interval based on a duration that the wave front resides within the at least one spatial region. Slow conduction activity is identified for the at least one spatial region based on comparing the indication of conduction velocity relative to a threshold. Conduction data is stored in memory to represent each slow conduction event.Type: ApplicationFiled: May 4, 2018Publication date: November 7, 2019Inventors: QING LOU, JEFFREY B. ADAIR, QINGGUO ZENG, PING JIA, RYAN BOKAN, CONNOR EDEL, RAHSEAN ELLIS, BRIAN P. GEORGE, RAJA GHANEM, TIMOTHY G. LASKE
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Publication number: 20190304186Abstract: In an example, an n-dimensional method of fundamental solution (MFS) is used to compute reconstructed electrical activity on a cardiac envelope based on geometry data and electrical data, where n is a positive integer greater than three. The electrical data represents electrical activity measured non-invasively from a plurality of locations distributed on a body surface of a patient, and the geometry data represents three-dimensional body surface geometry for the locations distributed on the body surface where the electrical activity is measured and three-dimensional heart geometry for the cardiac envelope.Type: ApplicationFiled: April 2, 2018Publication date: October 3, 2019Inventors: YONG WANG, QINGGUO ZENG, PING JIA, QING LOU
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Publication number: 20190290154Abstract: This disclosure provides one or more computer-readable media having computer-executable instructions for performing a method. The method includes storing geometry data representing a primary geometry of a cardiac envelope that includes nodes distributed across the cardiac envelope and geometry of a body surface that includes locations where electrical signals are measured. The body surface is spaced apart from the cardiac envelope. The method also includes perturbing the primary geometry of the cardiac envelope a given distance and direction to define the perturbed geometry of the cardiac envelope including nodes spaced from the nodes of the primary geometry. The method also includes computing reconstructed bipolar electrical signals on the nodes of the primary cardiac envelope based on the electrical signals measured from the body surface and the geometry data, including the primary and perturbed geometries of the cardiac envelope.Type: ApplicationFiled: March 23, 2018Publication date: September 26, 2019Inventors: YONG WANG, QING LOU, QINGGUO ZENG, PING JIA
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Publication number: 20190282112Abstract: Systems and methods for cardiac fast firing (e.g., atrial fast firing) detection perform frequency analysis on channels of collected cardiac waveform data and test the data for outlier frequency complex content that is of higher frequency than baseline frequency complex content associated with cardiac fibrillation (e.g., atrial fibrillation) or other arrhythmogenic activity. Anatomical regions from whence the cardiac fast firing originates can be displayed in real time on an epicardial surface map via a graphical display, aiding administration of therapy. Prior to such detection, QRST complex removal can be performed to ensure that ventricular activity does not infect the atrial fast firing analysis. A frequency-based method for QRST complex removal is also disclosed.Type: ApplicationFiled: March 14, 2019Publication date: September 19, 2019Inventors: Ping JIA, Qingguo ZENG, Timothy G. LASKE, Qing LOU
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Publication number: 20190274568Abstract: This disclosure relates to integrated channel integrity detection and to reconstruction of electrophysiological signals. An example system includes a plurality of input channels configured to receive respective electrical signals from a set of electrodes. An amplifier stage includes a plurality of differential amplifiers, each of the differential amplifiers being configured to provide an amplifier output signal based on a difference between a respective pair of the electrical signals. Channel detection logic is configured to provide channel data indicating an acceptability of each of the plurality of input channels based on an analysis of a common mode rejection of the amplifier output signals.Type: ApplicationFiled: March 6, 2018Publication date: September 12, 2019Inventors: SHAHABEDIN SHAHDOOSTFARD, QINGGUO ZENG, PING JIA, BRIAN P. GEORGE, KEVIN PONZIANI, QING LOU, DANIEL VARGHAI, JEFFREY B. ADAIR
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Publication number: 20190271531Abstract: This disclosure relates to localization and tracking of an object. As one example, measurement data can be stored in memory to represent measured electrical signals at each of a plurality of known measurement locations in a given coordinate system in response to an applied signal at an unknown location in the given coordinate system. A dipole model cost function has parameters representing a dipole location and moment corresponding to the applied signal. A boundary condition can be imposed on the dipole model cost function. The unknown location in the given coordinate system, corresponding to the dipole location, can then be determined based on the stored measurement data and the dipole model cost function with the boundary condition imposed thereon.Type: ApplicationFiled: May 17, 2019Publication date: September 5, 2019Inventors: QINGGUO ZENG, PING JIA, CHARULATHA RAMANATHAN, LIJUN YU, JEFF BURRELL, BRIAN GEORGE, QING LOU, RYAN BOKAN, SONIYA BHOJWANI
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Patent number: 10376173Abstract: An example method includes performing amplitude-based detection to determine location of R-peaks for a plurality of electrograms. The method also includes performing wavelet-based detection to determine location of R-peaks for the plurality of electrograms. The method also includes adjusting the location of the R-peaks determined by the wavelet-based detection of R-peaks based on the location of R-peaks determined by the amplitude-based detection of R-peaks. The method also includes storing, in memory, R-peak location data to specify R-peak locations for the plurality of electrograms based on the adjusting.Type: GrantFiled: April 27, 2017Date of Patent: August 13, 2019Assignee: CARDIOINSIGHT TECHNOLOGIES, INC.Inventors: Brian P. George, Meredith E. Stone, Qingguo Zeng, Qing Lou, Connor S. Edel, Ping Jia, Jeffrey B. Adair, Vladimir A. Turovskiy, Matthew J. Sabo, Ryan M. Bokan, Ketal C. Patel, Charulatha Ramanathan, John E. Anderson, Andrew E. Hoover, Cheng Yao
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Patent number: 10323922Abstract: This disclosure relates to localization and tracking of an object. As one example, measurement data can be stored in memory to represent measured electrical signals at each of a plurality of known measurement locations in a given coordinate system in response to an applied signal at an unknown location in the given coordinate system. A dipole model cost function has parameters representing a dipole location and moment corresponding to the applied signal. A boundary condition can be imposed on the dipole model cost function. The unknown location in the given coordinate system, corresponding to the dipole location, can then be determined based on the stored measurement data and the dipole model cost function with the boundary condition imposed thereon.Type: GrantFiled: August 31, 2015Date of Patent: June 18, 2019Assignee: CARDIOINSIGHT TECHNOLOGIES, INC.Inventors: Qingguo Zeng, Ping Jia, Charulatha Ramanathan, Lijun Yu, Jeff Burrell, Brian George, Qing Lou, Ryan Bokan, Soniya Bhojwani
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Publication number: 20180310850Abstract: One or more non-transitory computer-readable media have instructions executable by a processor and programmed to perform a method. The method includes analyzing the electrical data to locate one or more wave front lines over a given time interval. The electrical data represents electrophysiological signals distributed across a cardiac envelope for one or more time intervals. A respective trajectory is determined for each wave end of each wave front line that is located across the cardiac envelope over the given time interval. A set of connected trajectories are identified based on a duration that the trajectories are connected to each other by a respective wave front line during the given time interval. A connectivity association is characterized for the trajectories in the set of connected trajectories.Type: ApplicationFiled: April 27, 2017Publication date: November 1, 2018Inventors: QINGGUO ZENG, QING LOU, RYAN M. BOKAN, PING JIA, CONNOR S. EDEL, CHARULATHA RAMANATHAN
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Publication number: 20170319089Abstract: An example method includes analyzing morphology and/or amplitude of each of a plurality of electrophysiological signals across a surface of a patient's body to identify candidate segments of each signal satisfying predetermined conduction pattern criteria. The method also includes determining a conduction timing parameter for each candidate segment in each of the electrophysiological signals.Type: ApplicationFiled: April 27, 2017Publication date: November 9, 2017Inventors: QING LOU, MEREDITH E. STONE, QINGGUO ZENG, JEFFREY B. ADAIR, CONNOR S. EDEL, PING JIA, KEVIN R. PONZIANI, BRIAN P. GEORGE, RYAN M. BOKAN, MATTHEW J. SABO, VLADIMIR A. TUROVSKIY, KETAL C. PATEL, CHARULATHA RAMANATHAN
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Publication number: 20170319088Abstract: An example method includes performing amplitude-based detection to determine location of R-peaks for a plurality of electrograms. The method also includes performing wavelet-based detection to determine location of R-peaks for the plurality of electrograms. The method also includes adjusting the location of the R-peaks determined by the wavelet-based detection of R-peaks based on the location of R-peaks determined by the amplitude-based detection of R-peaks. The method also includes storing, in memory, R-peak location data to specify R-peak locations for the plurality of electrograms based on the adjusting.Type: ApplicationFiled: April 27, 2017Publication date: November 9, 2017Inventors: BRIAN P. GEORGE, MEREDITH E. STONE, QINGGUO ZENG, QING LOU, CONNOR S. EDEL, PING JIA, JEFFREY B. ADAIR, VLADIMIR A. TUROVSKIY, MATTHEW J. SABO, RYAN M. BOKAN, KETAL C. PATEL, CHARULATHA RAMANATHAN, JOHN E. ANDERSON, ANDREW E. HOOVER, CHENG YAO
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Publication number: 20160354012Abstract: An example method includes storing invasive position data representing different positions of one or more sensors in a given coordinate system within a volume defined by an electromagnetic field and storing non-invasive position data representing different positions of a plurality of control points in the given coordinate system determined from a position of one or more sensors. The method also includes computing internal geometry data based on the invasive position data, the internal geometry data representing a three-dimensional anatomical surface within a patient's body. The method also includes computing electrode geometry data based on the non-invasive position data, the electrode geometry data representing a location of each of a plurality of electrodes on an outer surface of the patient's body. Electrical activity sensed by the plurality of electrodes can be reconstructed onto an anatomical envelope within the patient's body.Type: ApplicationFiled: June 2, 2016Publication date: December 8, 2016Inventors: QINGGUO ZENG, PING JIA, CHARULATHA RAMANATHAN, QING LOU, RYAN BOKAN, BRIAN P. GEORGE