Abstract: The invention is directed to methods to inhibit p38-&agr; kinase using compounds of the formula 1

Abstract: A hollow cathode magnetron comprises an open top target within a hollow cathode. The open top target can be biased to a negative potential so as to form an electric field within the cathode to generate a plasma. The magnetron uses at least one electromagnetic coil to shape and maintain a density of the plasma within the cathode. The magnetron also has an anode located beneath the cathode. The open top target can have one of several different geometries including flat annular, conical and cylindrical, etc.

Abstract: The invention is directed to methods to inhibit p38-&agr; kinase using compounds of the formula 1

Abstract: The invention is directed to methods to inhibit p38-&agr; kinase using compounds of the formula 1

Abstract: The invention is directed to methods to inhibit p38-&agr; kinase using compounds of the formula 1

Abstract: The present invention pertains to methods for preventing metal or metal-derived material from flaking during sputter processing of substrates. Methods of the invention are particularly useful for non-planar sputter targets. The magnetic field configuration in a sputter apparatus is modulated during a pasting process. Flaking from regions of the target, shield, or other internal components of the sputter apparatus is inhibited by pasting methods which include encapsulation and optionally removal of material, for example by erosion via high density plasma.

Abstract: The invention is directed to inhibition of p38-a kinase using compounds of the formula 1

Abstract: The invention is directed to methods to inhibit p38-&agr; kinase using compounds of the formula 1

Abstract: The present invention provides a Vitex agnus castus extract wherein the extract is obtained by extracting dried and pulverized fruits of the plant Vitex agnus castus with a 90-100% ethanol solvent, separating the extraction solution from the rest of the plant material, removing the solvent from the extraction solution and recovering the extract. The present invention also provides for a dietary supplement comprising a Vitex agnus castus extract having a linoleic acid content of at least ten weight percent by the composition and a calcium source and the use of the extract and dietary supplement to treat conditions particularly affecting women.

Abstract: A bilayer mask employed for lift off has a top strip which bridges between first and second bilayer portions and is completely undercut so that when one or more materials is sputter deposited the materials do not form fences abutting recessed edges of a bottom layer in undercuts below a top layer. Sacrificial protective layers are formed on a sensor and lead layers for protecting these components while overlapping portions of these materials on the top of the sensor formed during deposition can be removed by ion beam sputtering, after which the sacrificial protective layers can be removed by ion milling or reactive ion etching.

Abstract: A PVD system comprises a hollow cathode magnetron with a downstream plasma control mechanism. The magnetron has a hollow cathode with a non-planar target and at least one electromagnetic coil to generate and maintain a plasma within the cathode. The magnetron also has an anode located between the cathode and a downstream plasma control mechanism. The control mechanism comprises a first, second and third electromagnetic coil beneath a mouth of the target, vertically spaced so as to form a tapered magnetic convergent lens between the target mouth and a pedestal of the magnetron.

Abstract: A PVD system comprises a hollow cathode magnetron with a capability of producing a high magnetic field for PVD and a low magnetic field for pasting. The high magnetic field is used for PVD and causes an optimal uniform film to form on a substrate but redeposits some metals onto a top portion of a target within the magnetron. The low magnetic field erodes redeposited materials from a top portion of a target within the magnetron.

Abstract: An x-ray tube apparatus includes a housing defining a chamber and an x-ray tube mounted therein. The x-ray tube includes an envelope defining an evacuated void in which an anode assembly is rotatably mounted to a bearing assembly. The anode assembly interacts with a cathode assembly for the production of x-rays. The bearing assembly includes a cooling channel that is defined within the bearing assembly to direct cooling fluid, such as oil, across an inner surface of the bearing housing. A flow director is located in a fluid input port in the housing and has a fluid input aperture for connecting the flow director to the heat removal system. A cavity is defined by the housing of the flow director and two fluid output apertures are in fluid communication with each other and the fluid input opening. One of the fluid output apertures supplies cooling fluid to the cooling channel in the bearing assembly and the other fluid output aperture supplies cooling fluid to the chamber in the housing.

Abstract: A PVD system comprises a hollow cathode magnetron with a capability of producing a high magnetic field for PVD and a low magnetic field for pasting. The high magnetic field is used for PVD and causes an optimal uniform film to form on a substrate but redeposits some metals onto a top portion of a target within the magnetron. The low magnetic field erodes redeposited materials from a top portion of a target within the magnetron.

Abstract: A PVD system comprises a hollow cathode magnetron with a downstream plasma control mechanism. The magnetron has a hollow cathode with a non-planar target and at least one electromagnetic coil to generate and maintain a plasma within the cathode. The magnetron also has an anode located between the cathode and a downstream plasma control mechanism. The control mechanism comprises a first, second and third electromagnetic coil beneath a mouth of the target, vertically spaced so as to form a tapered magnetic convergent lens between the target mouth and a pedestal of the magnetron.

Abstract: An x-ray tube includes an envelope defining an evacuated chamber in which an anode assembly is rotatably mounted to a bearing assembly and interacts with a cathode assembly for production of x-rays. The x-ray tube further includes a heat shield disposed in the envelope. The heat shield serves to reduce heat radiating from the anode assembly which is transferred to the bearing assembly or otherwise serves to insulate the bearing assembly from such radiated heat. The heat shield is brazed or otherwise bonded to the anode assembly and is comprised of a material having a low emissivity so that a minimum amount of heat radiates through the heat shield.