Abstract: This application provides a born-again TSK fuzzy classifier based on knowledge distillation. The born-again TSK fuzzy classifier based on knowledge distillation is denoted as CNNBaTSK, and a fuzzy rule of CNNBaTSK includes two parts: an antecedent part based on soft label information and a consequent part based on original data. A method for constructing the fuzzy rule of CNNBaTSK includes following steps: Step 1: taking, by the CNNBaTSK, the original data as input, obtaining a probability distribution of an output layer through a layer-by-layer neural expression, and introducing a distillation temperature to generate soft label information of DATASET; Step 2: partitioning the soft label information into five fixed fuzzy partitions to construct the fuzzy rule in a fuzzy part of the CNNBaTSK; Step 3: introducing the original data to calculate a consequent parameter, and optimizing the consequent parameter of CNNBaTSK using a non-iterative learning method.

Abstract: Provided is a method for preventing or treating a metabolic disorder, including administering to a subject a therapeutically effective amount of TRABID protein or a functionally related variant thereof, or a nucleic acid encoding TRABID protein or a functionally related variant thereof. Also provided is a method for reducing fat accumulation through TRABID-induced deubiquitination to promote autophagy activity and lipid metabolism.

Abstract: A surgical instrument includes: a handle and a working head connected with the handle, in which the handle or the working head provides a power; a firing sleeve assembly detachably connected with the working head, in which a clip-jaw is provided on a side of the firing sleeve assembly far away from the working head; and a clip-cartridge assembly inserted into the firing sleeve assembly and detachably connected with the working head. The working head includes: a firing drive assembly for driving the firing sleeve assembly to achieve closing or opening of the clip-jaw, a clip delivery drive assembly for driving the clip-cartridge assembly to deliver a ligating clip, and a switching assembly for transmitting the power to the firing drive assembly or the clip delivery drive assembly.

Abstract: A method of the present disclosure for producing methylammonium lead halide perovskite quantum dots includes providing a Pb-oleic acid solution containing a Pb source that is soluble in oleic acid, oleic acid, and a non-polar solvent, providing a methylammonium-oleic acid solution containing methylammonium acetate and oleic acid, providing a reaction solution of tetrabutylammonium halide and oleylamine, and mixing the Pb-oleic acid solution, the methylammonium-oleic acid solution, and the reaction solution.

Abstract: Provided is a method for preventing or treating a metabolic disorder, including administering to a subject a therapeutically effective amount of TRABID protein or a functionally related variant thereof, or a nucleic acid encoding TRABID protein or a functionally related variant thereof. Also provided is a method for reducing fat accumulation through TRABID-induced deubiquitination to promote autophagy activity and lipid metabolism.

Abstract: A method of the present disclosure for producing methylammonium lead halide perovskite quantum dots includes providing a Pb-oleic acid solution containing a Pb source that is soluble in oleic acid, oleic acid, and a non-polar solvent, providing a methylammonium-oleic acid solution containing methylammonium acetate and oleic acid, providing a reaction solution of tetrabutylammonium halide and oleylamine, and mixing the Pb-oleic acid solution, the methylammonium-oleic acid solution, and the reaction solution.