Abstract: Various examples are provided related to the application of a kernel neural network (KNN) to the analysis of high dimensional and ultrahigh dimensional data for, e.g., risk prediction. In one embodiment, a method includes training a KNN with a training set to produce a trained KNN model, determining a likelihood of a condition based at least in part upon an output indication of the trained KNN corresponding to one or more phenotypes, identifying treatment or prevention strategy for an individual based at least in part upon the likelihood of the condition. The KNN model includes a plurality of kernels as a plurality of layers to capture complexity between the data with disease phenotypes. The training set of data includes genetic information applied as inputs to the KNN and the phenotype(s), and the output indication is based upon analysis of data comprising genetic information from the individual by the trained KNN.

Abstract: A light-emitting diode display panel, a manufacturing method thereof, and an organic light-emitting diode display device are provided. The light-emitting diode display panel includes: a base substrate including a display region and a peripheral region surrounding the display region; a plurality of sub-pixels located in the display region and located at a side of the base substrate; a color-resistance layer located at a side of a second electrode in the sub-pixel away from the base substrate; and a light-blocking structure located in the peripheral region and being an annular structure surrounding the plurality of sub-pixels. The light-blocking structure includes a first light-blocking structure and a second light-blocking structure. The first light-blocking structure includes at least one interval extending in a direction from the display region pointing to the peripheral region. The second light-blocking structure at least fully fills the interval.

Abstract: Embodiments of the disclosure provide a method, apparatus, device, and storage medium for content capturing. The method includes, presenting a first capturing page corresponding to a single-segment capturing mode to capture a first video segment; in response to an indication of capturing completion being detected while the first capturing page is being presented, presenting a first editing page for editing at least the first captured video segment; and presenting a second capturing page to capture a second video segment based on an indication of new capturing being detected while the first editing page is being presented. In this way, it is possible for users to conduct content creating more easily and quickly, and different capturing requirements can further be met.

Abstract: This application provides a born-again TSK fuzzy classifier based on knowledge distillation. The born-again TSK fuzzy classifier based on knowledge distillation is denoted as CNNBaTSK, and a fuzzy rule of CNNBaTSK includes two parts: an antecedent part based on soft label information and a consequent part based on original data. A method for constructing the fuzzy rule of CNNBaTSK includes following steps: Step 1: taking, by the CNNBaTSK, the original data as input, obtaining a probability distribution of an output layer through a layer-by-layer neural expression, and introducing a distillation temperature to generate soft label information of DATASET; Step 2: partitioning the soft label information into five fixed fuzzy partitions to construct the fuzzy rule in a fuzzy part of the CNNBaTSK; Step 3: introducing the original data to calculate a consequent parameter, and optimizing the consequent parameter of CNNBaTSK using a non-iterative learning method.

Abstract: Provided is a method for preventing or treating a metabolic disorder, including administering to a subject a therapeutically effective amount of TRABID protein or a functionally related variant thereof, or a nucleic acid encoding TRABID protein or a functionally related variant thereof. Also provided is a method for reducing fat accumulation through TRABID-induced deubiquitination to promote autophagy activity and lipid metabolism.

Abstract: A surgical instrument includes: a handle and a working head connected with the handle, in which the handle or the working head provides a power; a firing sleeve assembly detachably connected with the working head, in which a clip-jaw is provided on a side of the firing sleeve assembly far away from the working head; and a clip-cartridge assembly inserted into the firing sleeve assembly and detachably connected with the working head. The working head includes: a firing drive assembly for driving the firing sleeve assembly to achieve closing or opening of the clip-jaw, a clip delivery drive assembly for driving the clip-cartridge assembly to deliver a ligating clip, and a switching assembly for transmitting the power to the firing drive assembly or the clip delivery drive assembly.

Abstract: A method of the present disclosure for producing methylammonium lead halide perovskite quantum dots includes providing a Pb-oleic acid solution containing a Pb source that is soluble in oleic acid, oleic acid, and a non-polar solvent, providing a methylammonium-oleic acid solution containing methylammonium acetate and oleic acid, providing a reaction solution of tetrabutylammonium halide and oleylamine, and mixing the Pb-oleic acid solution, the methylammonium-oleic acid solution, and the reaction solution.

Abstract: Provided is a method for preventing or treating a metabolic disorder, including administering to a subject a therapeutically effective amount of TRABID protein or a functionally related variant thereof, or a nucleic acid encoding TRABID protein or a functionally related variant thereof. Also provided is a method for reducing fat accumulation through TRABID-induced deubiquitination to promote autophagy activity and lipid metabolism.

Abstract: A method of the present disclosure for producing methylammonium lead halide perovskite quantum dots includes providing a Pb-oleic acid solution containing a Pb source that is soluble in oleic acid, oleic acid, and a non-polar solvent, providing a methylammonium-oleic acid solution containing methylammonium acetate and oleic acid, providing a reaction solution of tetrabutylammonium halide and oleylamine, and mixing the Pb-oleic acid solution, the methylammonium-oleic acid solution, and the reaction solution.