Patents by Inventor Qing Shi

Qing Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic amino acid compounds pharmaceutical compositions comprising same and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds
    Patent number: 6528505
    Abstract: Disclosed are compounds which inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits &bgr;-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Grant
    Filed: June 22, 1999
    Date of Patent: March 4, 2003
    Assignees: Elan Pharmaceuticals, Inc., Eli Lilly & Company
    Inventors: James E. Audia, Bruce A. Dressman, Qing Shi
  • Sham-sensitive terminal oxidase gene from xylose-fermenting yeast
    Patent number: 6391599
    Abstract: Disclosed is a SHAM-sensitive terminal oxidase (STO) gene from the xylose-fermenting yeast Pichia stipitis. Also disclosed is a mutant of Pichia stipitis in which the STO gene natively present in the wild-type yeast was disrupted. Mutants of Pichia stipitis having reduced expression of PsSTO were found to exhibit enhanced fermentation of xylose to ethanol.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: May 21, 2002
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Nian-Qing Shi, Thomas W. Jeffries
  • Disruption of the cytochrome C gene in xylose-fermenting yeast
    Patent number: 6071729
    Abstract: Disclosed is a xylose-fermenting mutant yeast strain exhibiting reduced expression of cytochrome c and enhanced fermentation of xylose relative to xylose-fermenting yeast strains in which cytochrome c is fully functional. Also disclosed is a method of producing ethanol from xylose by culturing a xylose-fermenting mutant yeast strain exhibiting reduced expression of cytochrome c in the presence of xylose-containing material.
    Type: Grant
    Filed: March 23, 1999
    Date of Patent: June 6, 2000
    Inventors: Thomas W. Jeffries, Nian-Qing Shi