Abstract: A surface of copper foil wound onto a guide roller 26 is irradiated with light. Specular light from the copper foil surface is received by CCD cameras 14a, and scattered light from the copper foil surface is received by CCD cameras 14b. When, in a region in which the amount of specular light received by the CCD cameras 14a is equal to or larger than a first threshold, a portion having a luminance equal to or larger than a second threshold is present, and when the amount of scattered light received by the CCD cameras 14b is smaller than a luminance average, that region is determined to be a defective copper portion.

Abstract: This invention relates generally to the field of growth factor. In particular, the invention provides an isolated nucleic acid fragment, comprising a sequence of nucleotides encoding a Kringle domain 1 of human hepatocyte growth factor (HGFK1). Proteins or peptides encoded by the HGFK1 nucleic acids are also provided. Compositions comprising HGFK1 nucleic acids, proteins, or functional derivatives or fragments are also provided. Methods for producing and/or using HGFK1 nucleic acids, proteins, or functional derivatives or fragments are further provided.