Abstract: Disclosed are an array cutting knife-type cotton topping machine and a control method thereof. The cotton topping machine includes cameras, controllers, a tacho-generator and a plurality of groups of topping assemblies arranged in a left-right direction; the cameras and the tacho-generator are connected to the controllers; and a plurality of topping devices staggered left and right are arranged for each planting row. In the present disclosure, by densely arranging low-cost topping devices and determining which topping devices are switched to an operating state for topping according to visually determined top bud positions, the potential problems in the prior art of the damage to other parts of the plant or the unnecessary intertwining of branches and leaves are avoided.

Abstract: The present invention relates to an SOS1 inhibitor with a pyrido-fused-six-membered ring structure, a preparation method therefor, and use thereof. The SOS1 inhibitor has the structural formula shown in formula (I) and an inhibitory activity on SOS1, and can be used to treat head and neck cancer, lung cancer, a mediastinal tumor, a gastrointestinal tumor, prostate cancer, testicular cancer, a gynecological tumor, breast cancer, renal and bladder cancer, an endocrine tumor, soft tissue sarcoma, osteosarcoma, rhabdomyosarcoma, mesothelioma, skin cancer, a peripheral nerve tumor, a central nervous system tumor, lymphoma, leukemia, Noonan syndrome, cardio-facio-cutaneous syndrome, and hereditary gingival fibromatosis and a related syndrome thereof.

Abstract: Aspects of the disclosure relate to compositions and methods for treating spinal muscular atrophy (SMA). The disclosure is based, in part, on isolated nucleic acids and vectors (e.g., viral vectors, such as rAAV vectors) encoding SMN1. In some embodiments, the expression of SMN 1 is driven by a native SMN 1 promoter or a variant thereof. In some embodiments, isolated nucleic acids and vectors of the disclosure have reduced toxicity and/or increased transgene expression relative to previously described SMN-encoding vectors.

Abstract: Aspects of the disclosure relate to compositions and methods for treating spinal muscular atrophy (SMA). The disclosure is based, in part, on isolated nucleic acids and vectors (e.g., viral vectors, such as rAAV vectors) encoding SMN1. In some embodiments, the expression of SMN1 is driven by a native SMN1 promoter or a variant thereof. In some embodiments, isolated nucleic acids and vectors of the disclosure have reduced toxicity and/or increased transgene expression relative to previously described SMN-encoding vectors.

Abstract: A method, computer system, and a computer program product for digital twin usage are provided. A first digital twin and performance data of the first digital twin are input into a first machine learning model to produce a second digital twin. The first machine learning model performs neural network-based data clustering. The first and second digital twins digitally represent a first physical entity. The second digital twin includes one or more changes from the first digital twin. Performance data of the second digital twin is analyzed.

Abstract: A preparation method and an application method of injectable polylactic acid (PLA) microspheres are provided, which relate to the field of biomedical technologies. The preparation method of the injectable PLA microspheres include: S01, preparing a spray solution; S02, performing homogeneous emulsification on the spray solution to obtain an emulsified spray solution; and S03, drying the emulsified spray solution. The spray solution includes an oil phase and an aqueous phase, and a weight ratio of the oil phase and the aqueous phase is 1-10:1-10. The oil phase includes PLA and an organic solvent, and the aqueous phase includes a surfactant, macromolecular substances and deionized water. A particle size of the injectable PLA microspheres is basically below 60 ?m, and the injectable PLA microspheres have a complete form, are independent of each other, do not exhibit agglomeration and have good biocompatibility, which can satisfy the requirement of the injection.

Abstract: A memory system includes a memory controller, a physical layer (PHY), and a memory (e.g., DRAM). Data is written to and read from the memory in different manners for different memory technologies, such as using different signals or signal timings for different memory technologies. Various runtime services specific to the memory technology are performed by the PHY rather than the memory controller. Examples of such runtime services include performing a training routine to train or re-train an interface between the PHY and the memory, performing a power management routine (e.g., to put the main memory in a self-refresh mode), and so forth.

Abstract: A lens-free microscopic imaging system (11), which is used to image microbeads (15) with pattern codes, includes an illumination system (11a) and an imaging system (11b). The illumination system (11a) includes an illumination light source (111) and an excitation light source (112). The imaging system (11b) includes an image sensor (113). The illumination light source (111) is used to emit illumination light to irradiate the microbeads (15), causing the irradiated microbeads (15) to be imaged on the image sensor. The excitation light source (112) is used to emit excitation light to excite the microbeads (15) to generate specific signals. The image sensor (113) is used to collect the images of the microbeads (15) and the specific signals to generate images. The imaging system (11) does not require a lens system. The present disclosure improves a detection efficiency of the microbeads (15).

Abstract: Embodiments of this application provide a cross-domain fault analysis method and system. According to the method and the system, whether a first single-domain network fault and a second single-domain network fault are caused by a same fault is determined based on correlation analysis on the first single-domain network fault and the second single-domain network fault in time dimension and service dimension. This resolves a problem of low fault diagnosis efficiency caused by a fact that operation and maintenance personnel needs to analyze each single-domain network fault because the same fault leads to a plurality of single-domain network faults.

Abstract: The present disclosure relates to cross-domain fault analysis methods and systems. According to the methods and the systems, whether a first single-domain network fault and a second single-domain network fault are caused by a same fault is determined based on correlation analysis on the first single-domain network fault and the second single-domain network fault in time dimension and service dimension.

Abstract: The present disclosure relates to cross-domain fault analysis methods and systems. According to the methods and the systems, whether a first single-domain network fault and a second single-domain network fault are caused by a same fault is determined based on correlation analysis on the first single-domain network fault and the second single-domain network fault in time dimension and service dimension.

Abstract: A system and method for recommending a similar incident in operations technologies and a related device are provided.

Abstract: A method for determining a fault root cause includes obtaining first fault information, where the first fault information includes M alarms, and M is an integer greater than or equal to 1; determining, from N pieces of known fault information based on the M alarms, at least one piece of known fault information that matches the first fault information, where each of the N pieces of known fault information includes a plurality of alarms; and determining, based on a fault root cause of the at least one piece of known fault information, information related to a root cause of the first fault information. The root cause of the first fault information is determined by using the known fault information that matches the first fault information.

Abstract: Provided are a mask, a sample collecting tube, and a pathogen collecting apparatus. The mask includes a mask body, a breather valve fixed on the mask body, and a sampling structure including a pathogen adsorption portion. The pathogen adsorption portion is disposed on an inner side of the breather valve and is adapted to adsorb pathogens in exhaled gas. The pathogen adsorption portion is adapted to enter the sample collecting tube to be in contact with a sample preservation solution in the sample collecting tube.

Abstract: A lens-free microscopic imaging system (11), which is used to image microbeads (15) with pattern codes, includes an illumination system (11a) and an imaging system (11b). The illumination system (11a) includes an illumination light source (111) and an excitation light source (112). The imaging system (11b) includes an image sensor (113). The illumination light source (111) is used to emit illumination light to irradiate the microbeads (15), causing the irradiated microbeads (15) to be imaged on the image sensor. The excitation light source (112) is used to emit excitation light to excite the microbeads (15) to generate specific signals. The image sensor (113) is used to collect the images of the microbeads (15) and the specific signals to generate images. The imaging system (11) does not require a lens system. The present disclosure improves a detection efficiency of the microbeads (15).

Abstract: A system and method for recommending a similar incident in operations technologies and a related device are provided.

Abstract: The present disclosure relates to new agents useful for anti-cancer therapy such as anti-cancer adoptive T-cell transfer (ACT) immunotherapy or immune check-point blockade therapy and related compositions, uses and methods thereof.

Abstract: A suspension thrust assembly, the suspension thrust assembly including a damping component and a rigid component, the damping component being overmolded and formed to the rigid component; the damping component including a damping radial portion; the rigid component including a rigid radial portion; where a ring-shaped damping component protrusion is provided on the damping radial portion, a ring-shaped rigid component groove is provided on the rigid radial portion, and the damping component protrusion is fitted in the rigid component groove.

Abstract: A video annotation system for deep learning based video analytics and corresponding methods of use and operation are described that significantly improve the efficiency of video data frame labeling and the user experience. The video annotation system described herein may be deployed at a network edge and may support various intelligent annotation functionality including annotation tracking, adaptive video segmentation, and execution of predictive annotation algorithms. In addition, the video annotation system described herein supports team collaboration functionality in connection with large-scale labeling tasks.