Abstract: Provided herein are methods and reagents for treating cancer. Methods of treating cancer are provided, comprising administering to a patient in need thereof an effective amount of a DKK1 peptide-loaded MHC antibody provided herein. The methods can further include administering an effective amount of chemotherapy or immunotherapy to said patient.

Abstract: Disclosed are antigen binding molecules that bind to Dickkopf-1 (DKK1) P20 peptide in the context of MHC-HLA-A2 (i.e., a DKK1-A2 complex). Such antigen binding molecules can by antibodies, antibody fragments, bi-specific antibodies, immunotoxins or the chimeric antigen receptor portion of a chimeric antigen receptor T cell. Also disclosed herein are methods of using said antigen binding molecules for the treatment of cancer.

Abstract: Provided herein are methods and reagents for treating cancer. Methods of treating cancer are provided, comprising administering to a patient in need thereof an effective amount of a DKK1 peptide-loaded MHC antibody provided herein. The methods can further include administering an effective amount of chemotherapy or immunotherapy to said patient.

Abstract: A composite material for light filtering, comprising: a polymeric matrix material and particles of neodymium compound doped in the polymeric matrix material. A lighting apparatus comprises the composite material, a method for determining a doping concentration of particles of neodymium compound in the composite material, and a method for determining a thickness of the composite material are also described.

Abstract: An apparatus including at least one light emitting diode (LED) module, configured to generate visible light; and at least one component comprising a compound comprising elements of neodymium fluoride and a dopant to lower a refractive index of the compound as compared to neodymium fluoride, the compound configured with the LED module to provide a desired light spectrum by filtering the visible light generated by the LED module.

Abstract: The present invention provides methods and compositions for Th9-cell mediated cancer therapy.

Abstract: A composite material for light filtering, comprising: a polymeric matrix material and particles of neodymium compound doped in the polymeric matrix material. A lighting apparatus comprises the composite material, a method for determining a doping concentration of particles of neodymium compound in the composite material, and a method for determining a thickness of the composite material are also described.

Abstract: The specification and drawings present a new apparatus such as a lighting apparatus, the apparatus comprising at least one LED (or OLED) module, configured to generate a visible light such as white light, and at least one component such as optical component comprising a compound consisting essentially of the elements neodymium (Nd) and fluorine (F), and optionally including one or more other elements. The lighting apparatus is configured to provide a desired light spectrum by filtering the generated visible light using the compound. The at least one component can comprise a NdFxOy compound with values of x and y determining a content ratio F/O, which may be adjusted during manufacturing of the NdFxOy compound to provide desired output light parameters of the apparatus including at least a desired output light spectrum realized by filtering the generated visible light using the NdFxOy compound.

Abstract: A lighting apparatus includes at least one light source generating a visible light and an optical component, the optical component includes a transparent, translucent or reflective substrate and a coating on a surface of the substrate to cause a color filtering effect to the visible light passing through the optical component, the coating includes a compound containing Nd3+ ions and F? ions.

Abstract: A lighting apparatus includes at least one light source generating a visible light and an optical component, the optical component includes a transparent, translucent or reflective substrate and a coating on a surface of the substrate to cause a color filtering effect to the visible light passing through the optical component, the coating includes a compound containing Nd3+ ions and F? ions.

Abstract: A composite material (11,21) for light filtering, comprising: a polymeric matrix material and particles of neodymium compound doped in the polymeric matrix material. A lighting apparatus (10,20) comprises the composite material. A method for determining a doping concentration of particles of neodymium compound in the composite material, and a method for determining a thickness of the composite material are also described.

Abstract: The specification and drawings present a new apparatus such as a lighting apparatus, the apparatus comprising at least one LED (or OLED) module, configured to generate a visible light such as white light, and at least one component such as optical component comprising a compound consisting essentially of the elements neodymium (Nd) and fluorine (F), and optionally including one or more other elements. The lighting apparatus is configured to provide a desired light spectrum by filtering the generated visible light using the compound. The at least one component can comprise a NdFxOy compound with values of x and y determining a content ratio F/O, which may be adjusted during manufacturing of the NdFxOy compound to provide desired output light parameters of the apparatus including at least a desired output light spectrum realized by filtering the generated visible light using the NdFxOy compound.

Abstract: An apparatus including at least one light emitting diode (LED) module, configured to generate visible light; and at least one component comprising a compound comprising elements of neodymium fluoride and a dopant to lower a refractive index of the compound as compared to neodymium fluoride, the compound configured with the LED module to provide a desired light spectrum by filtering the visible light generated by the LED module.

Abstract: A lighting apparatus includes at least one light source generating a visible light and an optical component, the optical component includes a transparent, translucent or reflective substrate and a coating on a surface of the substrate to cause a color filtering effect to the visible light passing through the optical component, the coating includes a compound containing Nd3+ ions and F? ions.

Abstract: The specification and drawings present a new apparatus such as a lighting apparatus, the apparatus comprising at least one LED (or OLED) module, configured to generate a visible light such as white light, and at least one component such as optical component comprising a compound consisting essentially of the elements neodymium (Nd) and fluorine (F), and optionally including one or more other elements. The lighting apparatus is configured to provide a desired light spectrum by filtering the generated visible light using the compound. The at least one component can comprise a NdFxOy compound with values of x and y determining a content ratio F/O, which may be adjusted during manufacturing of the NdFxOy compound to provide desired output light parameters of the apparatus including at least a desired output light spectrum realized by filtering the generated visible light using the NdFxOy compound.

Abstract: A composite material (11,21) for light filtering, comprising: a polymeric matrix material and particles of neodymium compound doped in the polymeric matrix material. A lighting apparatus (10,20) comprises the composite material. A method for determining a doping concentration of particles of neodymium compound in the composite material, and a method for determining a thickness of the composite material are also described.

Abstract: The specification and drawings present a new apparatus such as a lighting apparatus, the apparatus comprising at least one LED (or OLED) module, configured to generate a visible light such as white light, and at least one component such as optical component comprising a compound consisting essentially of the elements neodymium (Nd) and fluorine (F), and optionally including one or more other elements. The lighting apparatus is configured to provide a desired light spectrum by filtering the generated visible light using the compound. The at least one component can comprise a NdFxOy compound with values of x and y determining a content ratio F/O, which may be adjusted during manufacturing of the NdFxOy compound to provide desired output light parameters of the apparatus including at least a desired output light spectrum realized by filtering the generated visible light using the NdFxOy compound.

Abstract: A lamp is disclosed, which comprises a tubular, an elongate and two end-caps, wherein the tubular body comprises two ends of the tubular body; the elongate light source board is inside the tubular body along a longitudinal direction thereof, and the elongate light source board comprises at least one light source arranged thereon and two ends of the elongate light source board; two end-caps are adapted to seal the two ends of the tubular body respectively, and at least one end-cap is slidingly connected to one of the two ends of the tubular body and fixedly connected to one of the two ends of the elongate light source board. The lamp of the present disclosure can be adapted to temperature changes, and can avoid an overall length variation, and/or a bending deformation in appearance.

Abstract: A lamp is disclosed, which comprises a tubular, an elongate and two end-caps, wherein the tubular body comprises two ends of the tubular body; the elongate light source board is inside the tubular body along a longitudinal direction thereof, and the elongate light source board comprises at least one light source arranged thereon and two ends of the elongate light source board; two end-caps are adapted to seal the two ends of the tubular body respectively, and at least one end-cap is slidingly connected to one of the two ends of the tubular body and fixedly connected to one of the two ends of the elongate light source board. The lamp of the present disclosure can be adapted to temperature changes, and can avoid an overall length variation, and/or a bending deformation in appearance.

Abstract: A method of producing a population of CD8+ Tc9 lymphocytes is provided including priming a population of naïve CD8+ T cells by contacting the population of naïve CD8+ T cells with an immunogenic peptide, in the presence of a Tc9 supportive environment, thereby producing a population of CD8+ Tc9 lymphocytes which secrete IL-9. Purified populations of CD8+Tc9 cells are also disclosed herein, as are method for their use in the treatment of cancer in a subject.