Abstract: A program detection method includes receiving a program provided by a user, and obtaining, based on a query parameter and the program, a result of the program running in a weak memory environment. The query parameter indicates a maximum interval between two operations on which reordering occurs and that are of the program.

Abstract: Truncated dominant negative forms of CEBPB and CEBPD, and cell-penetrating forms thereof are described. Methods for using the truncated dominant negative forms of CEBPB and CEBPD proteins, and cell-penetrating forms thereof, for decreasing viability of neoplastic cells and treating cancer in a subject are also described.

Abstract: The present invention discloses a method for nitrogen removal of wastewater, which achieves the perfect combination of COD removal (Fenton oxidation) and nitrogen removal (Feammox) of wastewater, thereby avoiding the waste of reagents in traditional Fenton oxidation treatment of wastewater.

Abstract: A model management system adaptively refines a training dataset for more effective visual inspection. The system trains a machine learning model using the initial training dataset and sends the trained model to a client for deployment. The deployment process generates outputs that are sent back to the system. The system determines that performance of predictions for noisy data points are inadequate and determines a cause of failure based on a mapping of the noisy data point to a distribution generated for the training dataset across multiple dimensions. The system determines a cause of failure based on an attribute of the noisy datapoint that deviates from the distribution of the training dataset and performs refinement towards the training dataset based on the identified cause of failure. The system retrains the machine learning model with the refined training dataset and sends the retrained machine learning model back to the client for re-deployment.

Abstract: Techniques are provided for enriching samples for clinically-relevant cell-free (cfDNA), e.g., for downstream analysis. For example, cell-free DNA molecules having NCG end motifs can be selected, as such a subset has an increased proportion of the clinically-relevant cfDNA. Such NCG cfDNA molecules can be further selected based on size and/or location at tissue-specific hypomethylated sites for further enrichment. As another example, cell-free DNA molecules having CGN end motifs can be selected, as such a subset can have an increased proportion of the clinically-relevant cfDNA when located at tissue-specific hypermethylated sites. Such CGN cfDNA molecules can be further selected based on size.

Abstract: Fragmentation of cell-free DNA molecules is measured and used for various purposes, including determining methylation, e.g., at a particular site of a DNA molecule, at a particular genomic site in a reference genome for a biological sample (e.g., plasma, serum, urine, saliva) of cell-free DNA of a subject, or for a particular region in the reference genome for the biological sample (also just referred to as a sample). Various types of fragmentation measurements can be used, e.g., end motifs and cleavage profiles. Another purpose is determining a fractional concentration of DNA of a particular tissue type (e.g., clinically-relevant DNA). Another purpose is determining a pathology of a subject using a biological sample including cell-free DNA. The cell-free DNA can be of the subject or of a pathogen (e.g., a virus) in the subject's sample. Sites/regions that are hypermethylated, hypomethylated, 5hmC-enriched, and 5hmC-depleted for a particular tissue type can be used.

Abstract: The present invention relates to the field of solid-phase extraction, and particularly to a solid-phase extraction material, and a preparation method and use thereof. The preparation method includes prepolymerizing the monomers N-vinylpyrrolidone and divinylbenzene in the presence of a chain transfer agent, adding prepolymer dropwise to an emulsion of monodispersed seed microspheres, swelling, and reacting to prepare white spheres; and functionalizing the white spheres, to obtain the solid-phase extraction material. The solid-phase extraction material prepared by the reaction has good spherical morphology, large specific surface area, and high ion exchange capacity. The prepared solid-phase extraction material functions in the separation and enrichment of PPCPs by means of a variety of forces with a high extraction rate. The extraction rate is basically maintained between 85% and 105%, and acidic, alkaline, neutral and amphoteric substances is capable of being selectively separated.

Abstract: Disclosed is a top surface wave antenna of a spherical Tokamak, comprising a feedback waveguide, a brim, sub-waveguides, and a metal base. The lower end of the feed waveguide is connected to one end of the metal base, and one side of the feed waveguide is connected to the brim. The brim is towards a length direction of the metal base. A plurality of sub-waveguides are arranged on the metal base at equal intervals, the tops of the sub-waveguides are not higher than the height of the metal base, and the sub-waveguides are arranged in a rising line trend. The feed waveguide serves as a microwave input port. The top surface wave antenna of the spherical Tokamak is mainly used in a high-power Tokamak system and acts on the low-hybrid wave current driving together with an external antenna so as to obtain a better effect.

Abstract: Disclosed is a method for predicting collision severity, including: establishing a first learning model, and inputting vehicle data and collision accident scene feature data into the first learning model; obtaining a predicted collision acceleration curve outputted by the first learning model, the predicted collision acceleration curve being established based on a plane rectangular coordinate system; establishing a second learning model, and inputting the predicted collision acceleration curve, the occupant feature data and the restraint system feature data into the second learning model; obtaining a plurality of predicted collision kinematics and dynamics curves of human body parts outputted by the second learning model; generating a collision severity parameter according to the plurality of predicted collision kinematics and dynamics curves of the human body parts, the collision severity parameter being configured to evaluate the collision severity.

Abstract: An example image capture device includes a display configured to display captured images, a camera sensor, the camera sensor being disposed to receive light through at least a portion of the display, memory configured to store captured images, and one or more processors coupled to the camera sensor, the display, and the memory. The one or more processors are configured to receive a signal from a sensor. The one or more processors are configured to determine, based at least in part on the signal, a user interface mode. The user interface mode includes a first mode having a first number of black pixels or a second mode having a second number of black pixels. The first number is greater than the second number. The one or more processors are also configured to receive image data from the camera sensor.

Abstract: Porous structures are made from compositions that include hollow glass bodies and an inorganic powder. The inorganic powder may act as a rigid frame member, a crystallization agent, or both, which reduces the shrinkage of the porous structures during firing. The porous structures made therefrom have an open porosity of greater than 70% and reduced shrinkage of less than 10% compared to the green structures prior to firing. Methods for firing the green structures made from the compositions are also disclosed, the firing methods including reducing a temperature ramping rate of the green structures during a crystallization temperature range of the glass of the hollow bodies.

Abstract: An operator processing method includes obtaining a real-time shape of any to-be-output first tensor by combining in real time one or more micro-operators in a pre-constructed micro-operator library. Then, a micro-operator included in one combination (for example, a combination with optimal performance because different combinations have different performance) is selected for execution. Micro-operators in the micro-operator library are pre-compiled. Therefore, a compiler is not needed. In addition, shapes of the micro-operators are fixed and different, and are used as a “basis” of “shape space”.

Abstract: A method of plugging a filter, comprising: positioning a mask layer over the filter comprising a plurality of intersecting walls, wherein the intersecting walls define at least one channel between the intersecting walls; perforating the mask layer proximate the channel to form a hole, wherein the hole extends around a portion of a perimeter of the channel such that the mask layer defines a flap extending over a center of the channel; passing a plugging mixture into the channel through the hole in the mask layer; and sintering the plugging mixture to form a plug within the channel.

Abstract: The fragmentomic feature of which strand (3? or 5?), if any, overhangs the other at one or both ends double-stranded cell-free DNA fragments can be used to analyze a biological sample. The amount of fragments with the 3? strand overhanging the 5? strand, the 5? strand overhanging the 3? strand, and/or strands being even (blunt) at one or both ends can be used to determine the type of DNA or a level of condition, including cancer and nuclease activity deficiencies. Embodiments described herein allow for determining the amount of these different end modalities, unlike prior techniques. The end modality information can be paired with end motifs to further analyze biological samples. Related systems are also described.

Abstract: A battery pack is provided, including at least one layer of battery cells in a height direction thereof. Each layer of battery cells includes either or both of a plurality of rows and a plurality of columns of battery cells. The battery cells in each row are arranged end-to-end in a length direction of the battery pack. The rows are arranged in a width direction of the battery pack. At least a part of the battery cells in each row are staggered with corresponding battery cells in an immediately adjacent row of battery cells. The battery cells in each column are arranged end-to-end in the width direction of the battery pack. The columns are arranged in the length direction of the battery pack. At least a part of the battery cells in each column are staggered with corresponding battery cells in an immediately adjacent column of battery cells.

Abstract: The present invention relates to the field of solid-phase extraction, and particularly to a solid-phase extraction material, and a preparation method and use thereof. The preparation method includes prepolymerizing the monomers N-vinylpyrrolidone and divinylbenzene in the presence of a chain transfer agent, adding prepolymer dropwise to an emulsion of monodispersed seed microspheres, swelling, and reacting to prepare white spheres; and functionalizing the white spheres, to obtain the solid-phase extraction material. The solid-phase extraction material prepared by the reaction has good spherical morphology, large specific surface area, and high ion exchange capacity. The prepared solid-phase extraction material functions in the separation and enrichment of PPCPs by means of a variety of forces with a high extraction rate. The extraction rate is basically maintained between 85% and 105%, and acidic, alkaline, neutral and amphoteric substances is capable of being selectively separated.

Abstract: A reconfigurable optical add and drop multiplexer (ROADM) system is provided. The ROADM system may include a switching system which includes at least one first WSS optically coupled to a tapping coupler and configured to receive an input optical signal from a first circulator, transmit a drop optical signal to a demultiplexer to drop one or more first wavelength channels, and output a through optical signal. The switching system may also include at least one second WSS optically coupled to the at least one first WSS and a multiplexer and configured to receive an add optical signal to add one or more second wavelength channels, receive the through optical signal, and output an output optical signal to a second circulator, and at least one OCM configured to monitor the input optical signal and the output optical signal.

Abstract: This disclosure relates to antibody-drug conjugates (ADCs) comprising an anti-Trop-2 antibody. Provided herein are compositions comprising such ADCs, as well as methods of making and using the same.