Abstract: The present invention relates to a tetracyclic derivative, a method for preparing same and the use thereof in medicine. In particular, the present invention relates to a tetracyclic derivative represented by general formula (I), a method for preparing same and a pharmaceutically acceptable salt thereof, and the use thereof as a therapeutic agent, especially as a K-Ras GTPase inhibitor, with definitions of each substituent in general formula (I) being the same as of which are defined in the description.

Abstract: A drilling device and a drilling construction method for an electric power iron tower foundation are provided. The drilling device includes a hydraulic drilling unit, a multi-way connector, a compressed air conduit, a plurality of air compressor units, an air duct, a dust removal unit and an operation bench. The hydraulic drilling unit is capable of moving among a plurality of drilling platforms and among a plurality of hole positions on the plurality of drilling platforms and performing a drilling operation. The plurality of air compressor units are disposed in a fixing and mounting region that is between the plurality of drilling platforms, where compressed air outputted by the plurality of air compressor units flows jointly through the multi-way connector and then is transmitted to the hydraulic drilling unit through the compressed air conduit.

Abstract: Disclosed herein is a decontaminant aqueous solution for decontaminating diisocyanate drum, including 20-97 wt % of at least one alcohol or derivative thereof, based on the total weight of decontaminant aqueous solution, and an alkaline source in an amount effective to provide the solution a pH of at least 8. Further disclosed herein is a method for decontaminating diisocyanate residues in an emptied drum with the decontaminant aqueous solution.

Abstract: A construction method and an application of a digital human cardiovascular system based on hemodynamics are provided, the construction method comprising: partitioning various parts of a human body according to a distributed hemodynamic monitoring system, and determining granularity of a digital human model system; constructing an arterial blood flow transmission equation based on an elastic tube model for arteries, and defining physiological significance for characteristic values of the equation; inputting signals, characteristic values and hemodynamic parameters acquired by the distributed hemodynamic monitoring system into the digital human model system; and obtaining a dynamic and distributed digital human cardiovascular system through finite element calculation. An individual dynamic digital human model based on hemodynamics is constructed through the distributed characteristic values of various parts of the human body and the calculated hemodynamic parameters.

Abstract: A second blockchain system receives a first consensus message from a first blockchain system, the first blockchain system includes first nodes that provide services to at least a first account, and the second blockchain system includes second nodes that provide services to at least a second account. The first consensus message indicates a first plurality of the first nodes reaches a consensus for transferring a resource from the first account to the second account. The second blockchain system transfers the resource in the task to the second account. The transferring includes that a node in the second nodes adds the resource to the second account and generates a fourth block that records a completion of a transfer event. A second consensus message is transmitted from the second blockchain system to the first blockchain system in response to a second plurality of the second nodes completing the transfer event.

Abstract: A depth camera assembly (DCA) has a light source assembly, a mask, a camera assembly, and a controller. The light source assembly includes at least one light source. The mask is configured to generate an interference pattern that is projected into a target area. The mask has two openings configured to pass through light emitted by the at least one light source, and the light passed through the two openings forms an interference pattern across the target area. The interference pattern has a phase based on a position of the light source. The camera assembly is configured to capture images of a portion of the target area that includes the interference pattern. The controller is configured to determine depth information for the portion of the target area based on the captured images.

Abstract: A computer-implemented method, system and computer program product for improving performance for retrieving and reporting information from a data warehouse. A query (e.g., SQL query) is received. If a materialized view is present, and if such a materialized view was generated within the designated time frame, then the query is translated to query a materialized view. The translated query is then sent to a first data storage database of the data warehouse storing materialized views to be processed to obtain the materialized object associated with the query. If, on the other hand, the materialized view is not present, or the materialized view is present but has not been generated within the designated time frame, then the query is sent to the second data storage database of the data warehouse storing the original data without any modification to retrieve and report the appropriate information from the second data storage database.

Abstract: A method for producing an amino acid liquid fertilizer from waste feathers includes: acquiring an enzymatic hydrolysate by performing enzymolysis on feather powder with a complex enzyme; adding acid protease to the enzymatic hydrolysate for enzymolysis; and acquiring the amino acid liquid fertilizer by performing enzyme inactivation on a filtrate acquired by performing filtering after enzymolysis is completed, wherein the complex enzyme includes keratinase and amino acid peptidase. By adopting this method, the enzymolysis rate of the feathers reaches 80% or above and the prepared amino acid liquid fertilizer contains various kinds of amino acids (17 amino acids); and the content of the amino acid can reach 10.12% (by mass fraction) or above and the content of small peptide reaches 9.39% (by mass fraction), which reach the Chinese standard of the amino acid liquid fertilizers without concentration. Thus, the environmental-friendly amino acid liquid fertilizer can be prepared.

Abstract: A process for separating an alkylation product includes introducing a liquid phase alkylation product from an alkylation reaction unit into a first heat-exchanger directly or after being pressurized with a pressure pump and heat-exchanged with a vapor phase stream from the column top of a high-pressure fractionating column, then into a second heat-exchanger and subsequently into the high-pressure fractionating column. The vapor phase stream from the column top of the high-pressure fractionating column is heat-exchanged with the liquid phase alkylation product to be separated, a liquid phase stream from the column bottom of the high-pressure fractionating column is introduced into a low-pressure fractionating column and subjected to fractionation under a condition of 0.2 MPa-1.0 MPa, a low-carbon alkane is obtained from the column top of the low-pressure fractionating column, and a liquid phase stream obtained from the column bottom of the low-pressure fractionating column is an alkylation oil product.

Abstract: Enhancement of less dominant patterns for parametric wafer measurements. Dominant patterns are removed from the parametric pattern thereby revealing a less dominant pattern. The less dominant patterns can be used to identify root causes for yield loss that are not visible in the original parametric measurements.

Abstract: Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.

Abstract: Scheme for detection and classification of semiconductor equipment faults. Sensor traces are monitored and processed to separate known abnormal operating conditions from unknown abnormal operating conditions. Feature engineering permits focus on relevant traces for a targeted feature. A machine learning model is built to detect and classify based on an initial classification set of anomalies. The machine learning model is continuously updated as more traces are processed and learned.

Abstract: Provided are an organic light-emitting display panel and a display device. The organic light-emitting display includes an array substrate and organic light-emitting components each having an anode, a cathode and an organic functional layer. The organic functional layer includes an organic light-emitting layer, a first electron transmission layer, and a hole injection layer. LUMO1 and LUMO4 satisfy: |LUMO1?LUMO4|<1.7 eV. HOMO5 and HOMO4 satisfy: |HOMO5?HOMO4|<1 eV. A work function ?1 of the first dopant and a work function ?4 of the cathode satisfy: ?1<?4, and a work function ?2 of the second dopant and a work function ?3 of the anode satisfy: ?2>?3.

Abstract: A knitted stent and a knitted stent system are disclosed, the knitted stent system comprising the knitted stent, a knitted stent (100) is formed by spirally coiling a knitted wire about an axis in an interlaced manner. The knitted wire includes at least one elastic metal tube (110), each elastic metal tube (110) defining a first lumen and having a wall in which release holes (111) in communication with the first lumen are formed. The first lumen can serve as a drug receptacle. A drug can be filled in the receptacle and released from the release holes (111). In this way, the knitted stent (100) can be used as a base of a drug-loaded stent, thus solving the problem of poor geometric compliance and fatigue resistance arising from the use of conventional drug-loaded stents.

Abstract: A system for occluding a dissection tear includes a stent and at least one occluder and is such configured that the stent and the occluder are separate from each other prior to the delivery of the system to a targeted site and connect to each other after the delivery of the system to the targeted site. The stent and the occluder are separately delivered and released in a diseased blood vessel to significantly reduce the resistance encountered during delivery and release of the stent and the occluder. Moreover, when introducing the occluder into the false lumen, only the profile of the occluder needs to be adjusted, resulting in a lowered surgical difficulty and an improved surgical success rate.

Abstract: A stent delivery system and a method for mounting a stent (1) are disclosed. The stent delivery system includes a handle, an outer tube (52), a restraining member and delayed-release member (4) and is structurally simple and easy to use. During the release of a stent (1) from the restraining member, a proximal end of the stent (1) is always secured to the delayed-release member (4), avoiding the stent (1) from moving backward under the action of forces from the blood and thus resulting in improved positional accuracy of the release of the stent (1). Additionally, during the release of the stent (1) from the restraining member, a distal end of the stent (1) can be secured to an inner tube (51) by means of a fixed coil (32), and the proximal end of the stent (1) can remain fixed on the delayed-release member (4). This can avoid the stent (1) from moving forward or backward during the release of a middle section of the stent (1), allowing the stent (1) to be released under true accurate positional control.

Abstract: An occluder (100) and system. The occluder (100) includes a body (110) including a shaping wire (111) and a spring coil (112), the shaping wire (111) formed by a resilient metal wire and configured to have a predetermined shape, the spring coil (112) sleeved on the shaping wire (111) in order to shape the body (110) with the predetermined shape. Through maintaining the shape of the body (110) by means of the shaping wire (111), the body (110) is able to effectively block the breach (30) in aortic dissection treatments.

Abstract: Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.

Abstract: A nitrogen heterocyclic compound having a structure of Chemical Formula I is provided. z is 1 or 2, m and n are each 1 or 2, p and q are each 0, 1 or 2. X1-X6 are each independently nitrogen or carbon, and at least one of X1-X6 is nitrogen. R1, R2 and R3 are each independently C1-C10 linear or branched alkyl, substituted or unsubstituted aryl, fused aryl, an aromatic heterocyclic group, or a fused aromatic heterocyclic group. R1 and R2 may be otherwise a single bond. Ar1 and Ar2 are each substituted or unsubstituted aryl, fused aryl, an aromatic heterocyclic group, or a fused aromatic heterocyclic group. The nitrogen heterocyclic compound has a higher refractive index, can improve light extraction efficiency and luminous efficiency and alleviate angular dependence of luminescence when it is used as a capping layer CPL of an OLED device.

Abstract: A waterborne polyurethane dispersion is provided. The waterborne polyurethane dispersion is prepared in the presence of a chain extender N-aminoethylpiperazine (AEP) and exhibits good modulus while retaining limited solubility.