Abstract: A perpendicular magnetic recording (PMR) disk has a patterned template layer for the growth of the magnetic grains and the nonmagnetic material surrounding the grains. The template layer is a substantially planar platinum (Pt) or palladium (Pd) layer that is patterned to have Pt or Pd regions arranged in a hexagonal-close-packed (hcp) pattern with the Pt or Pd regions surrounded by Pt-oxide or Pd-oxide regions. The two separate regions of the template layer have different surface chemistries and energies, which provide a “chemical contrast” to impinging atoms during deposition of the metallic magnetic material and nonmagnetic (typically oxide) material, effectively guiding the deposition. The metallic magnetic material is preferentially deposited on the pristine, epitaxial Pt or Pd regions to form the magnetic grains, while the oxide migrates to the oxidized Pt or Pd regions due to the matching of lower surface energy.

Abstract: The present invention provides immunostimulatory combinations of TLR ligands and therapeutic and/or prophylactic methods that include administering an immunostimulatory combination to a subject. In general, the immunostimulatory combinations described herein can provide an increased immune response compared to other immunostimulatory combinations and/or compositions.

Abstract: The present disclosure relates to a method for fabricating an ion-implanted bit-patterned medium. The method includes providing a medium, the medium having a magnetic layer and a substrate and the magnetic layer includes migrating components. The method further includes forming a patterned mask layer on the surface of the magnetic layer and then ion-implanting the medium through the patterned mask layer, wherein the exposed portions of the magnetic layer comprise trench regions, the covered portions of the magnetic layer comprise island regions, and the transition areas between the trench regions and the island regions comprise boundary regions, wherein the island regions have more favorable magnetic properties than the trench regions. The method also includes annealing the medium, wherein the migrating components diffuse from inside the island regions towards the trench regions.

Abstract: In one embodiment, a method includes: depositing a plurality of nanoparticles on a substrate; and forming a monolayer of the nanoparticles on the substrate via self-assembly, where each of the nanoparticles comprises a nanoparticle core grafted to one or more oligomers and/or polymers, where each of the polymers and/or oligomers includes at least a first functional group configured to bind to the nanoparticles. In another embodiment, a method includes: depositing a plurality of nanoparticles on a substrate; and forming a monolayer of the nanoparticles on the substrate via self-assembly, where the nanoparticles each comprise a nanoparticle core grafted to one or more oligomers and/or polymers, each of the polymers and/or oligomers including a first terminal functional group configured to bind to the nanoparticles, and an optional second terminal functional group configured to bind to the substrate, where the substrate comprises guiding features configured to direct the self-assembly of the nanoparticles.

Abstract: In one embodiment, a structure includes: a substrate; and a monolayer of nanoparticles positioned above the substrate, where the nanoparticles are each grafted to one or more oligomers and/or polymers, and where each of the polymers and/or oligomers includes at least a first functional group configured to bind to the nanoparticles. In another embodiment, a structure includes: a substrate; a structured layer positioned above the substrate, the structured layer comprising a plurality of nucleation regions and a plurality of non-nucleation regions; and a crystalline layer positioned above the structured layer, where the plurality of nucleation regions have a pitch in a range between about 5 nm to about 20 nm.

Abstract: A perpendicular magnetic recording (PMR) disk has a patterned template layer for the growth of the magnetic grains and the nonmagnetic material surrounding the grains. The template layer is a substantially planar platinum (Pt) or palladium (Pd) layer that is patterned to have Pt or Pd regions arranged in a hexagonal-close-packed (hcp) pattern with the Pt or Pd regions surrounded by Pt-oxide or Pd-oxide regions. The two separate regions of the template layer have different surface chemistries and energies, which provide a “chemical contrast” to impinging atoms during deposition of the metallic magnetic material and nonmagnetic (typically oxide) material, effectively guiding the deposition. The metallic magnetic material is preferentially deposited on the pristine, epitaxial Pt or Pd regions to form the magnetic grains, while the oxide migrates to the oxidized Pt or Pd regions due to the matching of lower surface energy.

Abstract: In some embodiments, a web-browser-based presentation and report requests over a network may be facilitated. A request for a first report may be obtained from a user system through a web browser. The first report request may comprise a selection of one or more template or filter combinations for formatting the first report. Control of the web browser may be returned to enable a user to use the web browser to perform one or more other tasks while the first report request is being processed. The one or more other tasks may comprise requesting another report or other task. The first report request may be processed by obtaining and formatting the first report in accordance with the one or more selected template or filter combinations of the first report request. The formatted first report may be transmitted over the network to the web browser of the user system.

Abstract: A piezoelectric microcantilever for sensing compounds or molecules. The piezoelectric microcantilever, may include at least one electrode, an insulation layer, a receptor, an immobilization layer, a non-piezoelectric layer and a piezoelectric layer The sensor is capable of self actuation and detection. The piezoelectric layer may be constructed from a highly piezoelectric thin lead magnesium niobate-lead titanate film, a highly piezoelectric thin zirconate titanate film, a highly piezoelectric lead-free film. Methods of using the sensors and flow cells and arrays including the sensors are also described.

Abstract: A branched stent graft, a convey system comprising thereof and manufacturing method thereof, the branched stent graft includes a main body (100) and a side branch (200), at least a portion of a lowermost stent section of the side branch (200) closest to the main body (100) is not stitched to the cover of the side branch from a lower end to an upper end, the at least a portion of the lowermost stent section is located on a side of the side branch corresponding to a folding direction of the side branch. After deployed, the branched stent graft has an effective supporting force at the base portion of the side branch. In addition, during the deployment of the stent, the side branch can expand to a maximal extent even when the positioning is slightly inaccurate. Further, vascular stenosis or occlusion will not be caused even when subsequent endothelialization occurs.

Abstract: A perpendicular magnetic recording disk includes a template layer below a Ru or Ru alloy underlayer, with a granular Co alloy recording layer formed on the underlayer. substrate. The template layer comprises nanoparticles spaced-apart and partially embedded within a polymer material, with the nanoparticles protruding above the surface of the polymer material. A seed layer covers the surface of the polymer material and the protruding nanoparticles and an underlayer of Ru or a Ru alloy covers the seed layer. The protruding nanoparticles serve as the controlled nucleation sites for the Ru or Ru alloy atoms. The nanoparticle-to-nanoparticle distances can be controlled during the formation of the template layer. This enables control of the Co alloy grain diameter distribution as well as grain-to-grain distance distribution.

Abstract: A continuous-media perpendicular magnetic recording disk has a granular recording layer (RL) with controlled grain pitch distribution and controlled long range ordering of the grains. The disk includes a substrate with a template layer for the RL that comprises a blend of at least two different sized nanoparticles. The nanoparticles have a nanoparticle core with attached polymer ligands. The nanoparticle cores protrude above the surface of the template layer to provide a nonplanar surface topology. The blend of two sizes of nanoparticles causes the RL to have low grain pitch distribution and a disruption of long range ordering so that there are no large magnetic rafts. One of the nanoparticles types has a diameter greater than 105% of the diameter of the other nanoparticle type and is present in the total blend of nanoparticles of between about 5% and 35% or between about 55% and 90%.

Abstract: A network-based system for enabling users connected over the network to an OLAP system to select formatting options for reports requested for processing by the OLAP system. The system enables a user to select the format for each report in a workbook or for a stand-alone report. The format specified may be multiple levels of format that are applied in a hierarchical manner including global formats that apply to all reports in a workbook, report formats which apply to specific reports in the workbooks, attribute/element/metric formats which apply to specific attributes, elements, and metrics of a report, and value formats which apply to specific values within an element of a report. The formats specified may also comprise merged report formats, combined grid and graphs within a report and an autoformat that enables each recipient of the report to specify the format in which that recipient views the report when the report is received.

Abstract: According to one embodiment, a structure includes a substrate; an epitaxial seed layer positioned above the substrate, the epitaxial seed layer including a plurality of nucleation regions and a plurality of non-nucleation regions; and a crystalline layer positioned above the epitaxial seed layer, where the epitaxial seed layer has a crystallographic orientation substantially along an axis perpendicular to an upper surface of the substrate.

Abstract: A continuous-media perpendicular magnetic recording disk has a granular recording layer (RL) with controlled grain pitch distribution and controlled long range ordering of the grains. The disk includes a substrate with a template layer for the RL that comprises a blend of at least two different sized nanoparticles. The nanoparticles have a nanoparticle core with attached polymer ligands. The nanoparticle cores protrude above the surface of the template layer to provide a nonplanar surface topology. The blend of two sizes of nanoparticles causes the RL to have low grain pitch distribution and a disruption of long range ordering so that there are no large magnetic rafts. One of the nanoparticles types has a diameter greater than 105% of the diameter of the other nanoparticle type and is present in the total blend of nanoparticles of between about 5% and 35% or between about 55% and 90%.

Abstract: A stent graft (5) comprises a tubular graft member (4), and a plurality of sloping stent members (3) substantially coaxial with and coupled to the tubular graft member (4). Each of the sloping stent members (3) comprises multiple uneven apexes characterizing a round tubular configuration with a distal end and a proximal end disposed about a longitudinal axis. The distal apexes of the sloping stent member (3) are arranged in substantially the same plane substantially horizontal to the longitudinal axis of the sloping stent member and the proximal apexes are arranged in a sloping plane oblique to the longitudinal axis.

Abstract: In one general embodiment, a magnetic medium includes a recording layer having at least three exchange control layers each having a magnetic moment less than 100 emu/cc, and four magnetic layers separated from one another by the exchange control layers. An uppermost of the magnetic layers is doped with oxygen. In another general embodiment, a magnetic medium includes a recording layer having at least three exchange control layers and four magnetic layers separated from one another by the exchange control layers. An uppermost of the magnetic layers has an oxygen content of greater than 0.5 vol %. An average pitch of magnetic grains in a lowermost of the magnetic layers is 9 nm or less. A lowermost of the magnetic layers has an oxide content of at least 20 vol %.

Abstract: The present invention relates to novel respiratory syncytial virus (RSV) F peptides and compositions comprising them. The present invention also relates to methods of evaluating anti-RSV antibody binding to F peptides. The present invention also relates to antibodies that immunospecifically bind to an F peptide of the present invention. The invention further provides methods and protocols for the administration of F peptides and/or antibodies that immunospecifically bind to F peptides for the prevention, neutralization, treatment of RSV infection. Additionally, the methods of the invention may be useful for the treatment, prevention and the amelioration of symptoms associated with RSV infection.

Abstract: A piezoelectric microcantilever for sensing compounds or molecules. The piezoelectric microcantilever, may include at least one electrode, an insulation layer, a receptor, an immobilization layer, a non-piezoelectric layer and a piezoelectric layer The sensor is capable of self actuation and detection. The piezoelectric layer may be constructed from a highly piezoelectric thin lead magnesium niobate-lead titanate film, a highly piezoelectric thin zirconate titanate film, a highly piezoelectric lead-free film. Methods of using the sensors and flow cells and arrays including the sensors are also described.

Abstract: Provided herein are pharmaceutical formulations comprising a one-armed, anti-c-met antibody and uses of the same.

Abstract: A branched stent graft comprises a main body portion and a branch portion. Each of the main body portion and the branch portion includes a stent and a tubular graft. The stent of the main body portion includes a plurality of stent segments, at least one of which is a varying-height stent segment (102). The stent of the branch portion includes one or more stent segments, at least one of which is a varying-height stent segment (103). The distance between the proximal-most stent segment of the branch portion and the main body portion is in the range of 2-8 mm. A positioning ring (105) may be used at a side opening which connects the branch portion and the main body portion, and the positioning ring (105) can be sutured inside the graft of the main body, between the graft of the main body and the graft of the branch, or outside the graft of the branch.