Abstract: A system and method to forecast oil production and estimated ultimate recovery of oil from a multiply-fractured horizontal shale oil well. The method includes determining oil flow behavior of the oil well during linear stage flow and pseudo boundary stage flow of a well. Oil production forecasts and estimated ultimate recovery are determined based on the flow behaviors of the well and historical oil production rate data obtained from sensors disposed in or around the well. The system includes said sensor for measuring properties of the well and, optionally, a computer processor for executing the method.

Abstract: Methods, computing systems, and computer-readable media for forecasting oil recovery from a well. The method includes obtaining bottom-hole pressures, production rates, and a reservoir pressure for the well, and calculating pressure normalized rates based thereon. The method also includes forecasting a forecasted bottom-hole pressure for a first material balance time, based on the plurality of bottom-hole pressures, and forecasting a forecasted pressure normalized rate for the first material balance time based on the pressure normalized rates.

Abstract: Provided are multispecific binding proteins and methods for using these multispecific binding proteins to modulate the activation state of immune cells, such as T-cells (e.g., cytotoxic T-cells). Also provided are methods of modulating an immune response (e.g., cell killing by cytotoxic T-cells) in a subject (e.g., a human subject). Also provided are nucleic acids, expression vectors and host cells encoding the multispecific binding proteins.