Patents by Inventor Qinghao Xu

Qinghao Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTOXIN-II VARIANTS AND METHODS OF USE THEREOF
    Publication number: 20220054590
    Abstract: The present invention relates to Protoxin-II variants, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Application
    Filed: August 9, 2021
    Publication date: February 24, 2022
    Inventors: Mack FLINSPACH, Alan WICKENDEN, Ross FELLOWS, Qinghao XU, Andrew PIEKARZ
  • Protoxin-II variants and methods of use
    Patent number: 11083776
    Abstract: The present invention relates to Protoxin-II variants, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: August 10, 2021
    Assignee: JANSSEN BIOTECH, INC.
    Inventors: Mack Flinspach, Alan Wickenden, Ross Fellows, Qinghao Xu, Andrew Piekarz
  • Protoxin-II variants and methods of use
    Patent number: 10975129
    Abstract: The present invention relates to Protoxin-II variants, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: April 13, 2021
    Assignee: JANSSEN BIOTECH, INC.
    Inventors: Mack Flinspach, Alan Wickenden, Ross Fellows, Robert Neff, Yi Liu, Rebecca Hagan, Qinghao Xu
  • PROTOXIN-II VARIANTS AND METHODS OF USE
    Publication number: 20200054712
    Abstract: The present invention relates to Protoxin-II variants, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Application
    Filed: November 4, 2019
    Publication date: February 20, 2020
    Inventors: Mack FLINSPACH, Alan WICKENDEN, Ross FELLOWS, Qinghao XU, Andrew PIEKARZ
  • PROTOXIN-II VARIANTS AND METHODS OF USE
    Publication number: 20200048316
    Abstract: The present invention relates to Protoxin-II variants, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Application
    Filed: April 17, 2017
    Publication date: February 13, 2020
    Inventors: Mack Flinspach, Alan Wickenden, Ross Fellows, Robert Neff, Yi Liu, Rebecca Hagan, Qinghao Xu
  • Protoxin-II variants and methods of use
    Patent number: 10463714
    Abstract: The present invention relates to Protoxin-II variants, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: November 5, 2019
    Assignee: JANSSEN BIOTECH, INC.
    Inventors: Mack Flinspach, Alan Wickenden, Ross Fellows, Qinghao Xu, Andrew Piekarz
  • Regulation of specific spinal neurons regulating pain transmission via chimeric toxins
    Patent number: 10022450
    Abstract: A chimeric toxin is disclosed comprising a peptide ligand specifically targeting neurons involved in pain processing; and a clostridial neurotoxin light chain, wherein the ligand is linked to the light chain. The methods of preparing such chimeric toxin and the method of using the chimeric toxin to regulate pain transmission are also disclosed.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: July 17, 2018
    Assignees: Wisconsin Alumni Research Foundation, The Regents of the University of California
    Inventors: Eric A. Johnson, Sabine Pellett, William H. Tepp, Tony L. Yaksh, Marc Marino, Qinghao Xu
  • Protoxin-II variants and methods of use
    Patent number: 9624280
    Abstract: The present invention relates to Protoxin-II variants, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: April 18, 2017
    Assignee: JANSSEN BIOTECH, INC.
    Inventors: Mack Flinspach, Alan Wickenden, Ross Fellows, Robert Neff, Yi Liu, Rebecca Hagan, Qinghao Xu
  • Regulation of Specific Spinal Neurons Regulating Pain Transmission
    Publication number: 20160361429
    Abstract: A chimeric toxin is disclosed comprising a peptide ligand specifically targeting neurons involved in pain processing; and a clostridial neurotoxin light chain, wherein the ligand is linked to the light chain. The methods of preparing such chimeric toxin and the method of using the chimeric toxin to regulate pain transmission are also disclosed.
    Type: Application
    Filed: August 19, 2016
    Publication date: December 15, 2016
    Inventors: Eric A. Johnson, Sabine Pellett, William H. Tepp, Tony L. Yaksh, Marc Marino, Qinghao Xu
  • Pain treatment using ERK2 inhibitors
    Patent number: 9506068
    Abstract: This application describes methods and compositions for reducing, inhibiting and/or treating pain that involve use of ERK2 inhibitors.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: November 29, 2016
    Assignee: Cornell University
    Inventors: Charles E. Inturrisi, Qinghao Xu, Sandra M. Garraway
  • PROTOXIN-II VARIANTS AND METHODS OF USE
    Publication number: 20160287666
    Abstract: The present invention relates to Protoxin-II variants, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Application
    Filed: April 4, 2016
    Publication date: October 6, 2016
    Inventors: Mack Flinspach, Alan Wickenden, Ross Fellows, Qinghao XU, Andrew Piekarz
  • Regulation of specific spinal neurons regulating pain transmission via chimeric toxins
    Patent number: 9447405
    Abstract: A chimeric toxin is disclosed comprising a peptide ligand specifically targeting neurons involved in pain processing; and a clostridial neurotoxin light chain, wherein the ligand is linked to the light chain. The methods of preparing such chimeric toxin and the method of using the chimeric toxin to regulate pain transmission are also disclosed.
    Type: Grant
    Filed: February 14, 2014
    Date of Patent: September 20, 2016
    Assignees: WISCONSIN ALUMNI RESEARCH FOUNDATION, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Eric A. Johnson, Sabine Pellett, William H. Tepp, Tony L. Yaksh, Marc Marino, Qinghao Xu
  • PAIN TREATMENT USING ERK2 INHIBITORS
    Publication number: 20150240241
    Abstract: This application describes methods and compositions for reducing, inhibiting and/or treating pain that involve use of ERK2 inhibitors.
    Type: Application
    Filed: January 26, 2015
    Publication date: August 27, 2015
    Inventors: Charles E. Inturrisi, Qinghao Xu, Sandra M. Garraway
  • PROTOXIN -II VARIANTS AND METHODS OF USE
    Publication number: 20150099705
    Abstract: The present invention relates to Protoxin-II variants, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Application
    Filed: October 3, 2014
    Publication date: April 9, 2015
    Inventors: Mack FLINSPACH, Alan Wickenden, Ross Fellows, Robert Neff, Yi Liu, Rebecca Hagan, Qinghao Xu
  • Pain treatment using ERK2 inhibitors
    Patent number: 8951979
    Abstract: This application describes methods and compositions for reducing, inhibiting and/or treating pain that involve use of ERK2 inhibitors.
    Type: Grant
    Filed: June 12, 2009
    Date of Patent: February 10, 2015
    Assignee: Cornell University
    Inventors: Charles E. Inturrisi, Qinghao Xu, Sandra M. Garraway
  • Regulation of Specific Spinal Neurons Regulating Pain Transmission
    Publication number: 20140255376
    Abstract: A chimeric toxin is disclosed comprising a peptide ligand specifically targeting neurons involved in pain processing; and a clostridial neurotoxin light chain, wherein the ligand is linked to the light chain. The methods of preparing such chimeric toxin and the method of using the chimeric toxin to regulate pain transmission are also disclosed.
    Type: Application
    Filed: February 14, 2014
    Publication date: September 11, 2014
    Inventors: Eric A. Johnson, Sabine Pellett, William H. Tepp, Tony L. Yaksh, Marc Marino, Qinghao Xu
  • PAIN TREATMENT USING ERK2 INHIBITORS
    Publication number: 20110293628
    Abstract: This application describes methods and compositions for reducing, inhibiting and/or treating pain that involve use of ERK2 inhibitors.
    Type: Application
    Filed: June 12, 2009
    Publication date: December 1, 2011
    Applicant: Cornell University
    Inventors: Charles E. Inturrisi, Qinghao Xu, Sandra M. Garraway
  • Device for hanging weights to an elongated bar member
    Patent number: 7789814
    Abstract: A compact device for attaching weights to an elongated rod. One embodiment of the device comprises a tubular member and two arms attached to the tubular member. The tubular member can be slid onto the end of the elongated rod. Each of the two arms has a plurality of hook-shaped openings. Each pair of the corresponding hook-shaped openings defines a pocket for receipt of a bar member, such as the handle of a dumbbell. One device can be attached to each end of the elongated rod for supporting a plurality of dumbbells on each end thereof to thereby convert pairs of dumbbells into a barbell. Other embodiments are described and shown.
    Type: Grant
    Filed: April 23, 2009
    Date of Patent: September 7, 2010
    Inventor: Qinghao Xu