Patents by Inventor Qingkai Zeng

Qingkai Zeng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11976139
    Abstract: A preparation method of sodium hyaluronate with a full molecular weight distribution (MWD) is provided, including: step 1): spraying hydrogen peroxide on a sodium hyaluronate solid raw material, and conducting an ultraviolet (UV) irradiation treatment; step 2): dissolving a sodium hyaluronate degradation material in water, and adjusting a pH to higher than 7.0; step 3): subjecting a sodium hyaluronate alkaline solution to an ultrasonic treatment; step 4): preparing the sodium hyaluronate solid raw material into a sodium hyaluronate solution with a concentration of 0.1% to 1% (w/v), and thoroughly mixing the sodium hyaluronate solution in an addition proportion of 20% to 60% (v/v) with the sodium hyaluronate alkaline solution obtained after the ultrasonic treatment; and step 5): subjecting a resulting mixed solution to an adsorption treatment with diatomaceous earth and activated carbon, filtering for concentration, and drying a resulting concentrate to obtain the sodium hyaluronate with a full MWD.
    Type: Grant
    Filed: July 31, 2022
    Date of Patent: May 7, 2024
    Assignees: MEYER BIO-MEDICINE CO., LTD., SHANDONG MEIMAO PHARMACEUTICAL CO., LTD., SHANDONG GUANTIANXIA BIOTECHNOLOGY CO., LTD.
    Inventors: Peixue Ling, Huarong Shao, Qingkai Zeng
  • Publication number: 20240002551
    Abstract: A preparation method of sodium hyaluronate with a full molecular weight distribution (MWD) is provided, including: step 1): spraying hydrogen peroxide on a sodium hyaluronate solid raw material, and conducting an ultraviolet (UV) irradiation treatment; step 2): dissolving a sodium hyaluronate degradation material in water, and adjusting a pH to higher than 7.0; step 3): subjecting a sodium hyaluronate alkaline solution to an ultrasonic treatment; step 4): preparing the sodium hyaluronate solid raw material into a sodium hyaluronate solution with a concentration of 0.1% to 1% (w/v), and thoroughly mixing the sodium hyaluronate solution in an addition proportion of 20% to 60% (v/v) with the sodium hyaluronate alkaline solution obtained after the ultrasonic treatment; and step 5): subjecting a resulting mixed solution to an adsorption treatment with diatomaceous earth and activated carbon, filtering for concentration, and drying a resulting concentrate to obtain the sodium hyaluronate with a full MWD.
    Type: Application
    Filed: July 31, 2022
    Publication date: January 4, 2024
    Applicants: MEYER BIO-MEDICINE CO., LTD., SHANDONG MEIMAO PHARMACEUTICAL CO., LTD., SHANDONG GUANTIANXIA BIOTECHNOLOGY CO., LTD.
    Inventors: Peixue LING, Huarong SHAO, Qingkai ZENG
  • Patent number: 11797611
    Abstract: An approach for a non-factoid question answering framework across tasks and domains may be provided. The approach may include training a multi-task joint learning model in a general domain. The approach may also include initializing the multi-task joint learning model in a specific target domain. The approach may include tuning the joint learning model in the target domain. The approach may include determining which task of the multiple tasks is more difficult for the multi-task joint learning model to learn. The approach may also include dynamically adjusting the weights of the multi-task joint learning model, allowing the model to concentrate on learning the more difficult learning task.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: October 24, 2023
    Assignee: International Business Machines Corporation
    Inventors: Wenhao Yu, Lingfei Wu, Yu Deng, Qingkai Zeng, Ruchi Mahindru, Sinem Guven Kaya, Meng Jiang
  • Publication number: 20230012063
    Abstract: An approach for a non-factoid question answering framework across tasks and domains may be provided. The approach may include training a multi-task joint learning model in a general domain. The approach may also include initializing the multi-task joint learning model in a specific target domain. The approach may include tuning the joint learning model in the target domain. The approach may include determining which task of the multiple tasks is more difficult for the multi-task joint learning model to learn. The approach may also include dynamically adjusting the weights of the multi-task joint learning model, allowing the model to concentrate on learning the more difficult learning task.
    Type: Application
    Filed: July 7, 2021
    Publication date: January 12, 2023
    Inventors: Wenhao Yu, LINGFEI WU, Yu Deng, Qingkai Zeng, Ruchi Mahindru, Sinem Guven Kaya, Meng Jiang