Abstract: This invention provides a process for sequencing nucleic acids using 3? modified deoxynucleotide analogues or 3? modified deoxyinosine triphosphate analogues, and 3? modified dideoxynucleotide analogues having a detectable marker attached thereto.

Abstract: The present application discloses an anthropogenic heat flux estimation method and system based on flux observation data. The method includes: performing grid division on the selected region, and acquiring building vector data, land utilization data and instrument observation data in the selected region; calculating and correcting sensible heat fluxes and latent heat fluxes of different underlying surface types in a vorticity correlator flux source region; calculating temporal-spatial distribution of the sensible heat flux and the latent heat flux of each grid in a large-aperture scintillometer flux source region, and calculating temporal-spatial distribution of an anthropogenic heat flux of each grid in the flux source region in combination with a surface energy balance equation; and constructing an anthropogenic heat flux estimation model based on a convolutional neural network, and accurately estimating temporal-spatial distribution of the anthropogenic heat flux of each grid in the selected region.

Abstract: The present disclosure provides a model training method, including: performing feature extraction from a speech sample to obtain a speech feature; inputting the speech feature into an encoding network of a to-be-trained model for encoding processing; decoding an intermediate encoding feature to obtain an additional loss; obtaining an encoding loss based on an encoding feature and an encoding label; obtaining a total encoding loss based on the additional loss, the encoding loss, and a preset first loss weight; inputting the encoding feature into a decoding network for decoding processing to obtain a total decoding loss; obtaining a total model loss based on the total encoding loss, the total decoding loss, and a preset second loss weight; updating parameters in the model based on the total model loss, and continuing to train the to-be-trained model according to the updated parameters until the total model loss converges, obtaining a trained model.

Abstract: This invention provides novel azido linkers for deoxynucleotide analogues having a detectable marker attached thereto.

Abstract: A speech recognition method. The method includes: performing speech activity detection on speech data to obtain multiple speech segments; determining, for each of the speech segments, a number of speakers involved in the each of the speech segments; for each of at least one of the speech segments with the determined number greater than 1: performing speech separation on the each of at least one of the speech segments to obtain multiple audio segments; performing speech recognition on each of the audio segments to obtain respective first speech recognition results for the audio segments; performing feature extraction on each of the audio segments to obtain respective voiceprint feature vectors; and performing clustering on the audio segments with respect to the speakers to obtain a clustering result; and obtaining a second speech recognition result for the speech data based on the clustering result and the respective first speech recognition results.

Abstract: A hot-humid climatic wind tunnel and a multi-field coupling control system therefor. A fan (18), a variable temperature device, a variable humidity device, a salt fog generator (8), a sky background radiation board (11), a solar radiation lamp array (12) and a rain generator (13) are mounted in a wind tunnel body (29).

Abstract: Disclosed is a method for siting heat wave monitoring stations based on risk evaluation, including: acquiring historical meteorological data of a target region, and preprocessing the historical meteorological data to generate a gridded associated meteorological data set; identifying historical high-temperature heat wave events based on the associated meteorological data set, and calculating parameters and summary indexes of heat wave feature of grids; evaluating station building priority of the grids based on spatial distribution features of the summary indexes; acquiring multi-source data, and evaluating a heat wave risk to generate a heat wave risk map; performing iterative computation using an optimization algorithm based on current station building information, temporal-spatial distribution features of meteorological factors and the heat wave risk map to determine alternative station building positions; and acquiring on-site survey information of each alternative station building position, and determining

Abstract: This invention provides a process for sequencing single-stranded DNA by employing a nanopore and modified nucleotides.

Abstract: The disclosure provides chromogenic and fluorogenic compounds comprising amino acid or peptide appendages that are capable of detecting an activity in a bioassay. Also provided herein are methods for detecting a biological activity in a sample with the subject chromogenic and fluorogenic compounds. In one embodiment, provided herein is a method for detecting endotoxin in a sample. Further provided herein are kits including the subject chromogenic and fluorogenic compounds for detecting a biological activity in a sample.

Abstract: This invention provides a process for sequencing single-stranded DNA by employing a nanopore and modified nucleotides.

Abstract: This invention provides a process for sequencing nucleic acids using 3? modified deoxynucleotide analogues or 3? modified deoxyinosine triphosphate analogues, and 3? modified dideoxynucleotide analogues having a detectable marker attached thereto.

Abstract: This invention provides novel azido linkers for deoxynucleotide analogues having a detectable marker attached thereto.

Abstract: This invention provides a process for sequencing nucleic acids using 3? modified deoxynucleotide analogues or 3? modified deoxyinosine triphosphate analogues, and 3? modified dideoxynucleotide analogues having a detectable marker attached thereto.

Abstract: This invention provides novel azido linkers for deoxynucleotide analogues having a detectable marker attached thereto.

Abstract: This invention provides a process for sequencing single-stranded DNA by employing a nanopore and modified nucleotides.

Abstract: This invention provides a process for sequencing single-stranded DNA employing modified nucleotides.

Abstract: This invention provides a process for making 3?-O-allyl-dGTP-PC-Biodopy-FL-510, 3?-O-allyl-dATP-PC-ROX, 3?-O-allyl-dCTP-PC-Bodipy-650 and 3?-O-allyl-dUTP-PC-R6G, and related methods.

Abstract: This invention provides a process for sequencing single-stranded DNA employing modified nucleotides.

Abstract: This invention provides a process for sequencing nucleic acids using 3? modified deoxynucleotide analogues or 3? modified deoxyinosine triphosphate analogues, and 3? modified dideoxynucleotide analogues having a detectable marker attached thereto.

Abstract: This invention provides a process for sequencing single-stranded DNA employing modified nucleotides.