Patents by Inventor Qingling Yang
Qingling Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220240823Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes, and associated architectures, as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: ApplicationFiled: January 29, 2021Publication date: August 4, 2022Applicant: Medtronic MiniMed, Inc.Inventors: Ashwin K. Rao, Qingling Yang, Ellis Garai, Daniel E. Pesantez
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Muting glucose sensor oxygen response and reducing electrode edge growth with pulsed current plating
Patent number: 11266332Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.Type: GrantFiled: August 27, 2019Date of Patent: March 8, 2022Assignee: Medtronic MiniMed, inc.Inventors: Ting Huang, Ashwin K. Rao, Rajiv Shah, Qingling Yang -
Publication number: 20220047193Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes as well as methods for making and using such sensors. The amperometric analyte sensor apparatus comprises: a base layer; a conductive layer disposed on the base layer and comprising a working electrode; an interference rejection membrane disposed on an electroactive surface of the working electrode, wherein the interference rejection membrane comprises poly(vinyl alcohol) (PVA) polymers crosslinked by an acid crosslinker, wherein the crosslinker is a dicarboxylic acid type monomer or a polymer comprising a carboxylic acid group; and an analyte sensing layer. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: ApplicationFiled: October 29, 2021Publication date: February 17, 2022Applicant: Medtronic MiniMed, Inc.Inventors: Qingling Yang, Robert C. Mucic
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MUTING GLUCOSE SENSOR OXYGEN RESPONSE AND REDUCING ELECTRODE EDGE GROWTH WITH PULSED CURRENT PLATING
Publication number: 20200060586Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.Type: ApplicationFiled: August 27, 2019Publication date: February 27, 2020Applicant: Medtronic MiniMed, Inc.Inventors: Ting Huang, Ashwin K. Rao, Rajiv Shah, Qingling Yang -
Muting glucose sensor oxygen response and reducing electrode edge growth with pulsed current plating
Patent number: 10426383Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.Type: GrantFiled: February 27, 2013Date of Patent: October 1, 2019Assignee: MEDTRONIC MINIMED, INC.Inventors: Ting Huang, Ashwin K. Rao, Rajiv Shah, Qingling Yang -
Publication number: 20190094169Abstract: The invention pertains to analyte sensors designed to include layered compositions that provide these sensors with enhanced functional and/or material properties including, for example, resistance to damage caused by ethylene oxide during sterilization processes. Embodiments of the invention include polyvinyl alcohol N-methyl-4(4?-formylstyryl)pyridinium (SbQ) polymer materials and methods for employing such materials during the ethylene oxide sterilization of glucose sensors.Type: ApplicationFiled: November 26, 2018Publication date: March 28, 2019Applicant: MEDTRONIC MINIMED, INC.Inventors: Rajiv Shah, Qingling Yang, Robert C. Mucic, Jenn-Hann Larry Wang
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Publication number: 20170311858Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes as well as methods for making and using such sensors. The amperometric analyte sensor apparatus comprises: a base layer; a conductive layer disposed on the base layer and comprising a working electrode; an interference rejection membrane disposed on an electroactive surface of the working electrode, wherein the interference rejection membrane comprises poly(vinyl alcohol) (PVA) polymers crosslinked by an acid crosslinker, wherein the crosslinker is a dicarboxylic acid type monomer or a polymer comprising a carboxylic acid group; and an analyte sensing layer. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: ApplicationFiled: April 27, 2016Publication date: November 2, 2017Applicant: Medtronic MiniMed, Inc.Inventors: Qingling Yang, Robert C. Mucic
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Publication number: 20150122645Abstract: Embodiments of the invention provide analyte sensors formed from layered materials that include polymeric enzyme compositions selected to provide advantageous material properties, as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: ApplicationFiled: November 7, 2013Publication date: May 7, 2015Inventors: Qingling Yang, Rajiv Shah, Robert C. Mucic, Mercedes M. Perez, Ting Huang
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Publication number: 20150122647Abstract: The invention pertains to analyte sensors designed to include layered compositions that provide these sensors with enhanced functional and/or material properties including, for example, resistance to damage caused by ethylene oxide during sterilization processes. Embodiments of the invention include polyvinyl alcohol N-methyl-4(4?-formylstyryl)pyridinium (SbQ) polymer materials and methods for employing such materials during the ethylene oxide sterilization of glucose sensors.Type: ApplicationFiled: November 4, 2014Publication date: May 7, 2015Inventors: Rajiv Shah, Qingling Yang, Robert C. Mucic, Jenn-Hann Larry Wang
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MUTING GLUCOSE SENSOR OXYGEN RESPONSE AND REDUCING ELECTRODE EDGE GROWTH WITH PULSED CURRENT PLATING
Publication number: 20140243634Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.Type: ApplicationFiled: February 27, 2013Publication date: August 28, 2014Applicant: Medtronic MiniMed, Inc.Inventors: Ting Huang, Ashwin K. Rao, Rajiv Shah, Qingling Yang -
Patent number: 8808532Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as electrodes formed from sputtered platinum compositions as well as layers of material selected to optimize the characteristics of a wide variety of sensor elements and sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: GrantFiled: January 20, 2011Date of Patent: August 19, 2014Assignee: Medtronic Minimed, IncInventors: Qingling Yang, Rajiv Shah, Xiaolong Li, Barry Phong Pham, Yiwen Li
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Patent number: 8608921Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as electrodes formed from sputtered platinum compositions as well as layers of material selected to optimize the characteristics of a wide variety of sensor elements and sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: GrantFiled: January 20, 2011Date of Patent: December 17, 2013Assignee: Medtronic MiniMed, Inc.Inventors: Xiaolong Li, Rajiv Shah, Qingling Yang, Yiwen Li, Barry Phong Pham
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Publication number: 20120186997Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as electrodes formed from sputtered platinum compositions as well as layers of material selected to optimize the characteristics of a wide variety of sensor elements and sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: ApplicationFiled: January 20, 2011Publication date: July 26, 2012Applicant: MEDTRONIC MINIMED, INC.Inventors: Xiaolong Li, Rajiv Shah, Qingling Yang, Yiwen Li, Barry Phong Pham
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Publication number: 20120190950Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as electrodes formed from sputtered platinum compositions as well as layers of material selected to optimize the characteristics of a wide variety of sensor elements and sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: ApplicationFiled: January 20, 2011Publication date: July 26, 2012Applicant: MEDTRONIC MINIMED, INC.Inventors: Qingling Yang, Rajiv Shah, Xiaolong Li, Barry Phong Pham, Yiwen Li
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Publication number: 20110082356Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: ApplicationFiled: October 1, 2009Publication date: April 7, 2011Applicant: Medtronic MiniMed, Inc.Inventors: Qingling Yang, Rajiv Shah, Megan E. Little, Chia-Hung Chiu
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Publication number: 20030108574Abstract: When tumor cells are incubated with N-propionyl mannosamine, the N-acetyl groups of their surface a2-8 polysialic acid are converted to N-propionyl groups. The resultant bio-engineered cancer cells can be killed and used as a allogenic or autologous therapy or vaccine. The presence of N-propionylated polysialic acid-specific antibodies is detected in animals immunized with the vaccine prior to tumor implantation. Mice immunized with the heat-killed cancer cells experience better protection against challenge with live autologous RMA-S cells than mice immunized with heat-killed autologous RMA-S cells. Killed cells having modified sialic acid groups on their surface may be used as an anti-cancer therapy or vaccine either alone or in combination with an anti-cancer compound, such as cyclophosphamide.Type: ApplicationFiled: August 21, 2002Publication date: June 12, 2003Inventors: Harold J. Jennings, Tianmin Liu, Qingling Yang