Patents by Inventor Qingping Jiang

Qingping Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11093782
    Abstract: A method for matching a license plate number, comprises: obtaining a first license plate number to be matched; obtaining a license plate number library, wherein the license plate number library includes at least one second license plate number; calculating, based on a visual similarity of characters, a difficult degree in editing a character string required to converting between each second license plate number and the first license plate number; and determining, according to the difficult degree in editing a character string, at least one second license plate number matched with the first license plate number.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: August 17, 2021
    Assignee: Hangzhou Hikvision Digital Technology Co., Ltd.
    Inventors: Longsheng Hu, Zhiming Shen, Qingping Jiang
  • Patent number: 10710962
    Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.
    Type: Grant
    Filed: May 28, 2016
    Date of Patent: July 14, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, David Sharpe, David Wen, Qingping Jiang
  • Publication number: 20200190037
    Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.
    Type: Application
    Filed: February 26, 2020
    Publication date: June 18, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, David Sharpe, Qingping Jiang, David Wen
  • Publication number: 20200026946
    Abstract: A method for matching a license plate number, comprises: obtaining a first license plate number to be matched; obtaining a license plate number library, wherein the license plate number library includes at least one second license plate number; calculating, based on a visual similarity of characters, a difficult degree in editing a character string required to converting between each second license plate number and the first license plate number; and determining, according to the difficult degree in editing a character string, at least one second license plate number matched with the first license plate number.
    Type: Application
    Filed: September 27, 2019
    Publication date: January 23, 2020
    Inventors: Longsheng HU, Zhiming SHEN, Qingping JIANG
  • Publication number: 20190367556
    Abstract: Methods of removing high molecular weight species, in particular aggregates, from antibody drug conjugate preparations, by contacting preparations of the antibody drug conjugate reaction mixture with a hydroxyapatite resin and selectively eluting the ADC from the resin using a gradient comprising sodium phosphate.
    Type: Application
    Filed: December 7, 2016
    Publication date: December 5, 2019
    Applicant: PFIZER INC.
    Inventors: Durgesh V. Nadkarni, Jeffry R. Borgmeyer, He Meng, Qingping Jiang
  • Publication number: 20170320830
    Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.
    Type: Application
    Filed: July 4, 2014
    Publication date: November 9, 2017
    Inventors: Anand Natrajan, David Sharpe, Qingping Jiang, David Wen
  • Patent number: 9575062
    Abstract: Hydrophilic, chemiluminescent acridinium compounds containing zwitterions are disclosed. These acridinium compounds, when used as chemiluminescent labels in immunochemistry assays and the like, exhibit decreased non-specific binding to solid phases and provide increased assay sensitivity.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: February 21, 2017
    Assignee: SIEMENS HEALTHCARE DIAGNOSTICS INC.
    Inventors: Anand Natrajan, David Sharpe, Qingping Jiang
  • Patent number: 9487480
    Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: November 8, 2016
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, David Sharpe, David Wen, Qingping Jiang
  • Publication number: 20160274094
    Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.
    Type: Application
    Filed: May 28, 2016
    Publication date: September 22, 2016
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, David Sharpe, David Wen, Qingping Jiang
  • Patent number: 9353056
    Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: May 31, 2016
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, David Sharpe, David Wen, Qingping Jiang
  • Publication number: 20140295575
    Abstract: Hydrophilic, chemiluminescent acridinium compounds containing zwitterions are disclosed. These acridinium compounds, when used as chemiluminescent labels in immunochemistry assays and the like, exhibit decreased non-specific binding to solid phases and provide increased assay sensitivity.
    Type: Application
    Filed: June 11, 2014
    Publication date: October 2, 2014
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
    Inventors: Anand Natrajan, David Sharpe, Qingping Jiang
  • Patent number: 8778624
    Abstract: Hydrophilic, chemiluminescent acridinium compounds containing zwitterions are disclosed. These acridinium compounds, when used as chemiluminescent labels in immunochemistry assays and the like, exhibit decreased non-specific binding to solid phases and provide increased assay sensitivity.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: July 15, 2014
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, David Sharpe, Qingping Jiang
  • Publication number: 20130065325
    Abstract: Zwitterion-containing compounds for the modification of hydrophobic molecules to improve their solubility and/or to lower their non-specific binding as provided. The zwitterion-containing compounds may be suitable for modification of detectable labels such as biotin and fluorescein to improve their solubility. The zwitterion-containing compounds may also be useful for the preparation of conjugates of proteins, peptides and other macromolecules or for crosslinking molecules and/or macromolecules.
    Type: Application
    Filed: May 18, 2011
    Publication date: March 14, 2013
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
    Inventors: Anand Natrajan, David Sharpe, David Wen, Qingping Jiang
  • Publication number: 20120225497
    Abstract: Hydrophilic, chemiluminescent acridinium compounds containing zwitterions are disclosed. These acridinium compounds, when used as chemiluminescent labels in immunochemistry assays and the like, exhibit decreased non-specific binding to solid phases and provide increased assay sensitivity.
    Type: Application
    Filed: November 12, 2010
    Publication date: September 6, 2012
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS INC.
    Inventors: Anand Natrajan, David Sharpe, Qingping Jiang
  • Patent number: 8119422
    Abstract: Chemiluminescent acridinium esters are provided which are fast light emitting and hydrolytically stable. The chemiluminescent acridinium esters are useful labels in assays for detecting or quantifying analytes.
    Type: Grant
    Filed: October 15, 2007
    Date of Patent: February 21, 2012
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, Qingping Jiang, David Sharpe
  • Patent number: 7875467
    Abstract: Chemiluminescent acridinium compounds are used in homogeneous assays to determine the concentration of an analyte in a sample without strong acid or strong base treatment. The chemiluminescent acridinium compounds include acridinium esters with electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus to inhibit pseudo-base formation, or acridinium sulfonamides with or without electron donating functional groups at the C2 and/or C7 position on the acridinium nucleus.
    Type: Grant
    Filed: November 21, 2007
    Date of Patent: January 25, 2011
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand A. Natrajan, Todd Sells, Hartmut Schroeder, Guohan Yang, David Sharpe, Qingping Jiang, Hana Lukinsky, Say-Jong Law
  • Patent number: 7785904
    Abstract: The present invention relates to hydrophilic, high quantum yield acridinium compounds. It has been discovered that the placement of electron-donating groups in the acridinium ring system increases the amount of light that is emitted by the corresponding acridinium compound when its chemiluminescence is triggered by alkaline peroxide. More specifically, it has been found that the placement of one or two hydrophilic, alkoxy groups at the C-2 and/or C-7 position of the acridinium ring system of acridinium compounds increases their quantum yield and enhances the aqueous solubility of these compounds. The present hydrophilic, high quantum yield, acridinium compounds are useful chemiluminescent labels for improving the sensitivity of immunoassays.
    Type: Grant
    Filed: June 19, 2007
    Date of Patent: August 31, 2010
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, Qingping Jiang, David Sharpe, James Costello
  • Publication number: 20100099077
    Abstract: Chemiluminescent acridinium esters are provided which are fast light emitting and hydrolytically stable. The chemiluminescent acridinium esters are useful labels in assays for detecting or quantifying analytes.
    Type: Application
    Filed: October 15, 2007
    Publication date: April 22, 2010
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, Qingping Jiang, David Sharpe
  • Publication number: 20090318627
    Abstract: Acridinium-functionalized solid-phase supports and methods for making acridinium-functionalized solid-phase supports are disclosed. The acridinium-functionalized solid-phase supports comprise a solid phase support linked to a chemiluminescent substituted acridinium compound through a linker group covalently attached to the nitrogen atom of the acridinium nucleus and the solid phase support as exemplified in FIG. 1.
    Type: Application
    Filed: February 6, 2007
    Publication date: December 24, 2009
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, David Sharpe, Jim Costello, Qingping Jiang
  • Patent number: 7611909
    Abstract: A method for the detection or quantitation of unlabeled target analyte in a biological sample, the method comprising labeling a target analyte for a biological sample suspected of containing unlabeled target analyte with an acridinium compound to form a labeled target analyte and providing the labeled target analyte to the biological sample, or providing the labeled target analyte to the biological sample, wherein the acridinium compound comprises an acridinium nucleus having an electron-donating substituent directly attached to the acridinium nucleus, with the electron-donating substituent attached at the C2 position. Chemiluminescent acridinium compounds useful in the method have emission maxima close to or in the near infrared (NIR) region (>590 nm).
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: November 3, 2009
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, Qingping Jiang, David Sharpe, Say-Jong Law