Patents by Inventor QingQing Zhang
QingQing Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240141070Abstract: Provided is an isolated antigen-binding protein, wherein the drug is used for the treatment of tumor, and the isolated antigen-binding protein comprises a PD-L1 binding moiety and an OX40 binding moiety, wherein: the OX40 binding moiety is capable of recognizing and/or binding amino acid residues G70 and/or F71 in a human OX40 extracellular domain; and the PD-L1 binding moiety is capable of recognizing and/or binding amino acid residues I54, Y56, E58, Q66 and/or R113 in an N-terminal IgV domain of human PD-L1. Further provided is a use of the isolated antigen-binding protein in preparing a drug, wherein the drug is used for the treatment of tumors.Type: ApplicationFiled: October 16, 2020Publication date: May 2, 2024Inventors: Ting XU, Pilin WANG, Kangping GUO, Yuhao JIN, Ting CHEN, Li GAO, Qingqing ZHANG
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Patent number: 11971307Abstract: According to the present disclosure, there is provided a device (2) and a method for measuring a wavelength for a laser device. The device (2) for measuring a wavelength for a laser device includes: a first optical path assembly and a second optical path assembly. The first optical path assembly and the second optical path assembly constitute a laser wavelength measurement optical path. The second optical path assembly includes: an FP etalon assembly (11) and an optical classifier (13). The homogenized laser beam passes through the FP etalon assembly (11) to generate an interference fringe. The optical classifier (13) is arranged after the FP etalon assembly (11) in the laser wavelength measurement optical path, and configured to deflect the laser beam passing through the FP etalon assembly (11).Type: GrantFiled: December 11, 2020Date of Patent: April 30, 2024Assignee: Beijing RSLaserOpto-Electronics Technology Co. LtdInventors: Guangyi Liu, Rui Jiang, Xiaoquan Han, Jiangshan Zhao, Pengfei Sha, Qingqing Yin, Hua Zhang
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Publication number: 20240124227Abstract: The present disclosure provides a whole-process automatic loading-and-unloading and logistics system, including an outer yarn preparation area, an inner yarn preparation area, a weaving area and an in-air conveying rail; the outer yarn preparation area is configured to have a carrier assembly, which delivers an outer yarn winding package to an outer yarn branch rail of a twisting machine in a twisting area via the out yarn main rail of the in-air conveying rail; in the inner yarn preparation area, the carrier assembly delivers an inner yarn winding package to an inner yarn branch rail of the twisting machine in the twisting area via the inner yarn main rail of the in-air conveying rail; in the twisting area, the carrier assembly delivers a yarn product to a yarn product donning rail in the weaving area via the yarn product main rail of the in-air conveying rail.Type: ApplicationFiled: December 21, 2022Publication date: April 18, 2024Inventors: Jian NIE, Pihua ZHANG, Ming ZHANG, Yanwei ZHANG, Lei WU, Yuchao YAN, Yongming LI, Longfei ZHANG, Qingqing LV, Huanian YANG
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Publication number: 20240126150Abstract: A support stand for photography includes a support main body having supporting ends and a mounting end and an adapting device provided at the mounting end. The supporting ends are formed on supporting legs of the support main body. The supporting legs can be unfolded to allow two adjacent supporting ends to move away from each other. The supporting legs can be folded to allow the two adjacent supporting ends to move close to each other and form a gap between two adjacent supporting legs. The adapting device includes a fixed seat provided with an adapting structure for mounting a first photographic equipment and a clamping seat configured to clamp a second photographic equipment. The clamping seat is rotatably connected to the fixed seat. The clamping seat can rotate toward a side where the supporting ends are located to be accommodated in the gap between the two adjacent supporting legs.Type: ApplicationFiled: January 19, 2023Publication date: April 18, 2024Applicant: Shenzhen Weiji Technology Co.,Ltd.Inventors: Qingqing ZOU, Wei WEI, Xinzhi WANG, Youjin XIAO, Jun ZHANG, Jianxiong XIA
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Publication number: 20240125011Abstract: A lifting system for inner yarn rails relates to the technical field of twisting and weaving equipment in factories, the system comprises an in-air conveying rail, and a carrier unit, wherein the in-air conveying rail is configured to convey the carrier unit, and the carrier unit is configured to carry a winding package; an inner yarn-carrier-lifting section is arranged on the in-air conveying rail, the inner yarn-carrier-lifting section is positioned on both sides of a twisting machine; when the inner yarn-carrier-lifting section rises, it communicates with the in-air conveying rail; when the inner yarn-carrier-lifting section descends, it approaches the position of a spindle bucket of the twisting machine. The winding packages delivered each time by one carrier unit can correspond to every spindle position of the twisting machine, dramatically improving the delivery efficiency of the winding packages.Type: ApplicationFiled: December 21, 2022Publication date: April 18, 2024Inventors: Jian NIE, Pihua ZHANG, Ming ZHANG, Yanwei ZHANG, Lei WU, Yuchao YAN, Yongming LI, Longfei ZHANG, Qingqing LV, Huanian YANG
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Publication number: 20240125010Abstract: The present disclosure provides a twisting machine for automatic donning, including an outer yarn branch rail arranged at the middle position of the twisting machine, wherein the outer yarn branch rail is positioned above the twisting machine, so as to successively drive the outer yarn carrier assembly to deliver the outer yarn winding package by suspending; further including an inner yarn branch rail arranged at the both sides of the twisting machine, the inner yarn branch rail is positioned above the twisting machine, so as to successively drive the inner yarn carrier assembly to deliver the inner yarn winding package by suspending. The forementioned structure enables the outer yarn winding package and the inner yarn winding package to be delivered high-efficiently in large scale by suspending and conveying, so as to largely reduce the labor intensity of operators and greatly improve production efficiency.Type: ApplicationFiled: December 21, 2022Publication date: April 18, 2024Inventors: Jian NIE, Pihua ZHANG, Ming ZHANG, Yanwei ZHANG, Lei WU, Yuchao YAN, Yongming LI, Longfei ZHANG, Qingqing LV, Huanian YANG
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Publication number: 20240104590Abstract: The present disclosure relates to an item information push method. The item information push method includes: acquiring a plurality of attribute value sets of a to-be-promoted item according to preset value sets of a plurality of specified attributes; for the each attribute value set, determining an estimated warehouse-out quantity of the to-be-promoted item on a plurality of promotion platforms, according to historical traffic and historical warehouse-out quantities corresponding to a plurality of reference items and the historical traffic corresponding to the to-be-promoted item, on the plurality of promotion platforms; setting attribute values of the plurality of specified attributes of the to-be-promoted item according to the determined estimated warehouse-out quantity corresponding to the each attribute value set and the one set of values in the each attribute value set and sending the set attribute values to the plurality of promotion platforms.Type: ApplicationFiled: November 2, 2021Publication date: March 28, 2024Inventors: Qingqing ZHANG, Shanlin LI, Rui MAO, Yang PAN
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Publication number: 20240096483Abstract: An adaptive control method and system for an upper limb rehabilitation robot based on a game theory and surface Electromyography (sEMG) is disclosed. A movement trajectory that a robot is controlled to run within a training time is designed during subject operation. An sEMG-based Back Propagation Neural Network (BPNN) muscle force estimation model establishes a nonlinear dynamic relationship between an sEMG signal and end force by constructing a three-layer neural network. A human-computer interaction system is analyzed by the game theory principle, and a role of the robot is deduced. The control rate between the robot and a subject is updated by Nash equilibrium, and adaptive weight factors of the robot and the subject are determined. The robot adaptively adjusts the training mode thereof according to a movement intention of the subject during operation and a weight coefficient obtained by the game theory principle.Type: ApplicationFiled: July 25, 2022Publication date: March 21, 2024Applicant: SOUTHEAST UNIVERSITYInventors: Hong ZENG, Qingqing CHEN, Xiao LI, Yinxin DUAN, Jianxi ZHANG, Aiguo SONG
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Patent number: 11927937Abstract: Disclosed is a prediction method for tool remaining life of a numerical control machine tool based on a hybrid neural model, including: constructing a hybrid neural network model, specifically including the following steps: constructing sample data according to the sampling frequency of tool data; obtaining a first feature vector representing the tool life by utilizing a convolutional neural network and a long short-term memory network; generating working condition signals of sampling points into a second feature vector representing the tool life by utilizing an NFM neural network; and inputting a current working time of a tool and the acquired feature vectors into a multi-layer perceptron for fusion to predict the tool life.Type: GrantFiled: October 31, 2023Date of Patent: March 12, 2024Assignee: INSTITUTE OF INDUSTRIAL INTERNET, CHONGQING UNIVERSITY OF POSTS AND TELECOMMUNICATIONSInventors: Qingqing Huang, Yan Han, Zhen Kang, Yan Zhang, Ping Wang
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Publication number: 20230417307Abstract: A muscle-like actuator comprises a motor with a rotatable drive shaft and a string with a shear thickening fluid (STF) embedded therein. One end of the string is attached to the drive shaft and the other end is connected to a load to form a twisted string actuator (TSA). By controlling the speed and current of the motor, the characteristics of the actuator can be changed. Multiple strings may be located in a flexible soft tube to improve the mechanical properties of the actuator.Type: ApplicationFiled: June 26, 2023Publication date: December 28, 2023Applicant: The University of Hong KongInventors: Ning XI, Qingqing ZHANG, Yafei ZHAO
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Patent number: 11467711Abstract: Systems and methods for displaying and associating context images with zones or devices of a security system or a home automation system are provided. Such systems and methods may include associating each of a plurality of zones or devices of the security system or the home automation system with a respective context image and displaying the respective context image for one of the plurality of zones or devices in response to a user interface of the security system or the home automation system receiving user input.Type: GrantFiled: December 21, 2017Date of Patent: October 11, 2022Assignee: Ademco Inc.Inventors: Xinyu Ma, Qingqing Zhang, Lu Yuan
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Patent number: 11396557Abstract: The present application provides a bispecific antibody or an antibody mixture with common light chains and a preparation method therefor. the present application also provides a nucleic acid molecule encoding the antibody or the mixture, a recombinant vector and a recombinant cell comprising the nucleic acid molecule, as well as a detection and quantitation method for the antibody or the mixture.Type: GrantFiled: September 16, 2020Date of Patent: July 26, 2022Assignee: Jiangsu Alphamab Biopharmaceuticals Co., Ltd.Inventors: Ting Xu, Tao Xu, Xiaoxiao Wang, Qian Li, Minjie Pang, Huimin Zhang, Li Han, Qingqing Zhang
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Patent number: 11390591Abstract: The present invention provides a 2,4,6-trisubstituted s-triazine compound represented by general formula (I) or pharmaceutically acceptable salts, prodrugs or solvates thereof, a preparation method therefor, and use of these compounds in preparing drugs for preventing or treating diseases associated with protein kinase and vimentin dysregulation, and cell vacuolization, and in particular, drugs for treating or preventing cancer growth and metastasis, tissue fibrosis and atherosclerosis.Type: GrantFiled: February 26, 2020Date of Patent: July 19, 2022Assignee: Aluda Pharmaceuticals, Inc.Inventors: Qizheng Yao, Jianping Wu, Ruihuan Chen, Lei Zhang, Shining Yao, Lian Mo, Qingqing Zhang
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Patent number: 11149621Abstract: An exhaust pipe assembly includes: an exhaust cavity; an exhaust port (234) and at least two air inlets (115) communicating with the exhaust cavity, the exhaust port (234) being disposed at an end of the exhaust pipe assembly; and a water inlet (114), a first part of a water inlet cavity (111), a second part of a water inlet cavity, a water counterflow cavity, and a water outlet (311) that are provided in the exhaust pipe assembly. The water inlets (114) are provided in the same number as the air inlets (115). The first part of the water inlet cavity (111) communicates with the first water inlet portion (114). The second part of the water inlet cavity communicates with the second water inlet portion (114). The water counterflow cavity communicates with the end of the second part of the water inlet cavity located at the exhaust port (234) of the exhaust pipe assembly. The water outlet (311) is disposed at a second end of the exhaust pipe assembly.Type: GrantFiled: December 28, 2017Date of Patent: October 19, 2021Assignee: WEICHAI POWER CO., LTDInventors: Yangyang Zhang, Hongshuang He, Qingqing Zhang, Bin Hou, Feng Yun, Chao Rong
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Patent number: 11138352Abstract: An additive manufacturing (AM) system includes a process distortion compensation computing system and an AM peripheral device. The process distortion compensation computing system determines a digital nominal model that represents a physical target object excluding a distortion, and a digital distortion model that represents the physical target object including at least one distortion. The AM peripheral device forms a three-dimensional (3D) physical object based on a digital compensation model. The process distortion compensation computing system also determines a digital skeletal model indicating a predicted change in at least one of the shape and volume of the nominal model, and generates the digital compensation model based on the skeletal model that compensates for the at least one distortion.Type: GrantFiled: June 5, 2019Date of Patent: October 5, 2021Assignee: HAMILTON SUNDSTRAND CORPORATIONInventors: Yanzhi Chen, Qingqing Zhang, Tahany Ibrahim El-Wardany, Ranadip Acharya, Colette Opsahl Fennessy, William K. Tredway
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Publication number: 20210070885Abstract: The present application provides a bispecific antibody or an antibody mixture with common light chains and a preparation method therefor. the present application also provides a nucleic acid molecule encoding the antibody or the mixture, a recombinant vector and a recombinant cell comprising the nucleic acid molecule, as well as a detection and quantitation method for the antibody or the mixture.Type: ApplicationFiled: September 16, 2020Publication date: March 11, 2021Inventors: Ting XU, Tao XU, Xiaoxiao WANG, Qian LI, Minjie PANG, Huimin ZHANG, Li HAN, Qingqing ZHANG
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Publication number: 20200340387Abstract: Exhaust pipe assembly (EPA) includes: exhaust cavity; exhaust port (EP) and at least two air inlets communicating with the exhaust cavity, the EP being disposed at an end of the EPA; and a water inlet, a first part of a water inlet cavity (WIC), a second part of a WIC, a water counterflow cavity (WCC), and a water outlet that are provided in the EPA. The water inlets are provided in the same number as the air inlets. The first part of the WIC communicates with the first water inlet portion (WIP). The second part of the WIC communicates with the second WIP. The WCC communicates with the end of the second part of the WIC located at the EP of the EPA. The water outlet is disposed at a second end of the EPA. The first part of the WIC and the WCC each communicate with the water outlet.Type: ApplicationFiled: December 28, 2017Publication date: October 29, 2020Inventors: Yangyang ZHANG, Hongshuang He, Qingqing Zhang, Bin Hou, Feng Yun, Chao Rong
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Patent number: 10808043Abstract: The present application provides a bispecific antibody or an antibody mixture with common light chains and a preparation method therefor. the present application also provides a nucleic acid molecule encoding the antibody or the mixture, a recombinant vector and a recombinant cell comprising the nucleic acid molecule, as well as a detection and quantitation method for the antibody or the mixture.Type: GrantFiled: January 8, 2016Date of Patent: October 20, 2020Assignee: Jiangsu Alphamab Biopharmaceuticals Co., Ltd.Inventors: Ting Xu, Tao Xu, Xiaoxiao Wang, Qian Li, Minjie Pang, Huimin Zhang, Li Han, Qingqing Zhang
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Publication number: 20200190042Abstract: The present invention provides a 2,4,6-trisubstituted s-triazine compound represented by general formula (I) or pharmaceutically acceptable salts, prodrugs or solvates thereof, a preparation method therefor, and use of these compounds in preparing drugs for preventing or treating diseases associated with protein kinase and vimentin dysregulation, and cell vacuolization, and in particular, drugs for treating or preventing cancer growth and metastasis, tissue fibrosis and atherosclerosis.Type: ApplicationFiled: February 26, 2020Publication date: June 18, 2020Inventors: QIZHENG YAO, JIANPING WU, RUIHUAN CHEN, LEI ZHANG, SHINING YAO, LIAN MO, QINGQING ZHANG
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Patent number: 10611736Abstract: The present invention provides a 2,4,6-trisubstituted s-triazine compound represented by general formula (I) or pharmaceutically acceptable salts, prodrugs or solvates thereof, a preparation method therefor, and use of these compounds in preparing drugs for preventing or treating diseases associated with protein kinase and vimentin dysregulation, and cell vacuolization, and in particular, drugs for treating or preventing cancer growth and metastasis, tissue fibrosis and atherosclerosis.Type: GrantFiled: May 11, 2017Date of Patent: April 7, 2020Assignee: Aluda Pharmaceuticals, Inc.Inventors: Qizheng Yao, Jianping Wu, Ruihuan Chen, Lei Zhang, Shining Yao, Lian Mo, Qingqing Zhang