Patents by Inventor Qing-shan Li

Qing-shan Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treating oxalate-related conditions
    Patent number: 9795657
    Abstract: The subject invention relates in one aspect to an oxalate degrading composition, which includes at least one oxalate degrading enzyme. The composition includes an enriched insoluble component of fungal bio sample, and the composition is effective to degrade oxalate at a pH of 1.9 or higher. The composition is protected from protease degradation such as pepsin, trypsin and chymotrypsin. The composition is capable of withstanding the conditions of the stomach, small intestines, and/or large intestines of a subject.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: October 24, 2017
    Assignee: CAPTOZYME, LLC
    Inventors: Aaron Cowley, Qing-Shan Li
  • Methods and Compositions for Treating Oxalate-Related Conditions
    Publication number: 20130108607
    Abstract: The subject invention relates in one aspect to an oxalate degrading composition, which includes at least one oxalate degrading enzyme. The composition includes an enriched insoluble component of fungal biosample, and the composition is effective to degrade oxalate at a pH of 1.9 or higher. The composition is protected from protease degradation such as pepsin, trypsin and chymotrypsin. The composition is capable of withstanding the conditions of the stomach, small intestines, and/or large intestines of a subject.
    Type: Application
    Filed: November 23, 2010
    Publication date: May 2, 2013
    Inventors: Aaron Cowley, Qing-Shan Li
  • Modified cytochrome P450 monooxygenases
    Patent number: 7981652
    Abstract: The present invention relates to modified cytochrome P450 monooxygenases with an altered substrate profile, to nucleic acid sequences coding therefor, to expression constructs and vectors, to recombinant microorganisms which comprise these vectors, and to processes for the microbiological production of terminally or subterminally hydroxylated aliphatic carboxylic acids.
    Type: Grant
    Filed: April 13, 2009
    Date of Patent: July 19, 2011
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernhard Hauer, Juergen Pleiss, Ulrich Schwaneberg, Jutta Schmitt, Markus Fischer, Rolf Schmid, Qing-shan Li
  • Cytochrome p450 monooxygenases and their use for oxidizing organic compounds
    Patent number: 7960155
    Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: June 14, 2011
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernhard Hauer, Juergen Pleiss, Ulrich Schwaneberg, Jutta Schmitt, Markus Fischer, Rolf Schmid, Qing-shan Li, Sabine Lutz-Wahl, Daniel Appel
  • Modified Cytochrome P450 Monooxygenases
    Publication number: 20100267083
    Abstract: The present invention relates to modified cytochrome P450 monooxygenases with an altered substrate profile, to nucleic acid sequences coding therefor, to expression constructs and vectors, to recombinant microorganisms which comprise these vectors, and to processes for the microbiological production of terminally or subterminally hydroxylated aliphatic carboxylic acids.
    Type: Application
    Filed: April 13, 2009
    Publication date: October 21, 2010
    Inventors: Bernhard Hauer, Juergen Pleiss, Ulrich Schwaneberg, Jutta Schmitt, Markus Fischer, Rolf Schmid, Qing-shan Li
  • Modified cytochrome p450 monooxygenases
    Patent number: 7531335
    Abstract: The present invention relates to modified cytochrome P450 monooxygenases with an altered substrate profile, to nucleic acid sequences coding therefor, to expression constructs and vectors, to recombinant microorganisms which comprise these vectors, and to processes for the microbiological production of terminally or subterminally hydroxylated aliphatic carboxylic acids.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: May 12, 2009
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernhard Hauer, Juergen Pleiss, Ulrich Schwaneberg, Jutta Schmitt, Markus Fischer, Rolf Schmid, Qing-shan Li