Patents by Inventor Qingsheng GUO

Qingsheng GUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230296518
    Abstract: An imaging system for multiplex detection of biomolecules, including at least a first optical path and a second optical path; the first optical path is from an excitation light source to an objective lens, and a filter set is provided between the excitation light source and the objective lens and is configured to guide excitation light from the excitation light source to the objective lens; the second optical path is from the objective lens to an image acquisition device, a reflector is provided between the objective lens and the image acquisition device and is configured to project the fluorescence received by the objective lens to the image acquisition device; the excitation light source includes at least a first excitation light source used for excitation of fluorescent signals and a second excitation light source used for excitation of light-initiated chemiluminescence signals The system simultaneously realizes fluorescence and light-initiated chemiluminescence imaging.
    Type: Application
    Filed: February 10, 2021
    Publication date: September 21, 2023
    Applicants: SHANGHAI JIAO TONG UNIVERSITY, Shanghai Mag-Gene NanoTech Co., Ltd.
    Inventors: QINGSHENG GUO, HONG XU, HONGCHEN GU
  • Publication number: 20230184685
    Abstract: A detection particle suitable for multiplex detection of biomolecules, including a microcarrier with an encoding function, detection microparticles connected to the microcarrier, where the detection microparticle is suitable for light-initiated chemiluminescent detection. A multifunctional detection particle integrating encoding identification, magnetic separation, and light-initiated chemiluminescent detection functions was prepared. And an imaging detection and analysis device for the multifunctional detection particle was provided. The provided detection particle suitable for multiplex detection of biomolecules can realize a highly sensitive, fast, and washing-free multiplex detection method, which greatly increases the types of biomolecules that can be detected by a single reaction, and can remove unreacted signal labeled molecules without washing during the whole process, thus simplifying experimental steps, and improving detection efficiency.
    Type: Application
    Filed: February 20, 2021
    Publication date: June 15, 2023
    Applicants: SHANGHAI JIAO TONG UNIVERSITY, Shanghai Mag-Gene NanoTech Co., Ltd.
    Inventors: QINGSHENG GUO, HONG XU, HONGCHEN GU, ZUYING FENG
  • Publication number: 20210387656
    Abstract: A bolster beam is correspondingly connected to a connection base by means of a damping unit; the radial dimensions of an outer wall of an inner supporting member and an inner wall of an outer supporting member gradually decrease from one end to the other end in a vertical direction; one of the inner supporting member and the outer supporting member is connected to the connection base, and the other one is connected to the bolster beam; when in use, the inner supporting member and the outer supporting member tend to be close to each other, and since surfaces, close to each other, of the two are configured to be tapered, the two can-not be relatively separated; when getting closer to each other, the inner supporting member and the outer supporting member produce a compression action on an intermediate buffer member, and the intermediate buffer member is elastically deformable.
    Type: Application
    Filed: September 11, 2019
    Publication date: December 16, 2021
    Applicant: CRRC ZHUZHOU LOCOMOTIVE CO., LTD.
    Inventors: Quanwei PU, Longjiang SHEN, Xiaoyan LI, Xinpeng ZHOU, Bin GAO, Yulong LIU, Wentao ZHANG, Han LUO, Qingsheng GUO, Jianhui JIANG, Ti XIAO, Pingping WANG, Wei ZENG