Patents by Inventor Qingshun Guo

Qingshun Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIMERIZATION DELIVERY SYSTEM FOR INTRACELLULAR DELIVERY OF MOLECULE
    Publication number: 20230054711
    Abstract: A multimerization delivery system that can be used to deliver a cargo molecule intracellularly. The multimerization delivery system can achieve high-efficiency endocytosis of a cargo molecule and high-efficiency release thereof from an endocytic vesicle, significantly improving the cytoplasmic delivery efficiency of the cargo molecule. Once the cargo molecule is available in the cytoplasm, the cargo molecule can play any role related thereto. The multimerization delivery system provides an effective means for affecting the biological mechanisms and pathways of cells, and can be used in various fields such as research, treatment, and diagnosis.
    Type: Application
    Filed: November 9, 2020
    Publication date: February 23, 2023
    Inventors: Shengxiang GE, Siyuan YU, Han YANG, Haifeng PAN, Shuling REN, Tingdong LI, Qingshun GUO, Junhui XIONG, Jun ZHANG, Ningshao XIA
  • COMPLEX FOR INTRACELLULAR DELIVERY OF MOLECULES
    Publication number: 20220265837
    Abstract: A fusion protein and a complex containing same, capable of being used for the intracellular delivery of cargo molecules. The fusion protein and complex can implement the efficient release of cargo molecules from endocytic vesicles, thereby significantly improving the cytoplasmic delivery efficiency of the cargo molecules. One cargo molecules can be obtained in cytoplasms, they can exert any function related thereto. The fusion protein and complex provide effective means for affecting biological mechanisms and pathways of cells, and can be used in various fields such as research, treatment, and diagnosis.
    Type: Application
    Filed: July 10, 2020
    Publication date: August 25, 2022
    Inventors: Shengxiang GE, Siyuan YU, Han YANG, Haifeng PAN, Shuling REN, Tingdong LI, Qingshun GUO, Junhui XIONG, Jun ZHANG, Ningshao XIA
  • Method for in-vitro preparation of double-layered virus-like particles of rotavirus
    Patent number: 9862933
    Abstract: The invention relates to a method for preparing double-layered virus-like particles of rotavirus in vitro. The method comprises the following steps: purifying rotavirus VP6 proteins from a lysis supernatant, and in vitro assembling double-layered virus-like particles consisting of VP2 proteins and VP6 proteins, wherein the proteins and the virus-like particles can be used for preventing or reducing the clinical symptoms caused by rotavirus infection.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: January 9, 2018
    Assignees: Xiamen University, Xiamen Innovax Biotech Co., Ltd.
    Inventors: Shengxiang Ge, Tingdong Li, Qingshun Guo, Feihai Xu, Jun Zhang, Ningshao Xia
  • Method for In-Vitro Preparation of Double-Layered Virus-Like Particles of Rotavirus
    Publication number: 20150252334
    Abstract: The invention relates to a method for preparing double-layered virus-like particles of rotavirus in vitro. The method comprises the following steps: purifying rotavirus VP6 proteins from a lysis supernatant, and in vitro assembling double-layered virus-like particles consisting of VP2 proteins and VP6 proteins, wherein the proteins and the virus-like particles can be used for preventing or reducing the clinical symptoms caused by rotavirus infection.
    Type: Application
    Filed: June 24, 2013
    Publication date: September 10, 2015
    Inventors: Shengxiang Ge, Tingdong Li, Qingshun Guo, Feihai Xu, Jun Zhang, Ningshao Xia