Patents by Inventor Qingwei HOU

Qingwei HOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Revaprazan hydrochloride polymorphs and preparation method therefor
    Patent number: 10005757
    Abstract: Provided are revaprazan hydrochloride polymorphs and a preparation method thereof. The method comprises a step of dissolving revaprazan hydrochloride in ethanol or aqueous solutions of ethanol having different proportions to perform recrystallization.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: June 26, 2018
    Assignee: Jiangsu Tasly Diyi Pharmaceutical Co., Ltd.
    Inventors: Wenzheng Liu, Guocheng Wang, Qingwei Hou, Hongguang Meng
  • Preparation method for revaprazan hydrochloride
    Patent number: 9981917
    Abstract: Provided is a preparation method for revaprazan hydrochloride, the method comprising: (1) the preparation of 4-hydroxyl-2-(4-fluoroaniline)-5,6-dimethylpyrimidine; (2) the preparation of 4-chloro-2-(4-fluoroaniline)-5,6-dimethylpyrimidine; (3) the preparation of revaprazan hydrochloride. The method has advantages such as simple operations, high product purity, good yield and suitability for industrial production.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: May 29, 2018
    Assignee: Jiangsu Tasly Diyi Pharmaceutical Co., Ltd.
    Inventors: Wenzheng Liu, Guocheng Wang, Qingwei Hou, Qiaoping Cui, Zhanyuan Zhu, Jinping Liu, Mingbo Yang, Hongguang Meng
  • REVAPRAZAN HYDROCHLORIDE POLYMORPHS AND PREPARATION METHOD THEREFOR
    Publication number: 20170334877
    Abstract: Provided are revaprazan hydrochloride polymorphs and a preparation method thereof. The method comprises a step of dissolving revaprazan hydrochloride in ethanol or aqueous solutions of ethanol having different proportions to perform recrystallization.
    Type: Application
    Filed: November 12, 2015
    Publication date: November 23, 2017
    Inventors: Wenzheng Liu, Guochang Wang, Qingwei Hou, Hongguang Meng
  • PREPARATION METHOD FOR REVAPRAZAN HYDROCHLORIDE
    Publication number: 20170267646
    Abstract: Provided is a preparation method for revaprazan hydrochloride, the method comprising: (1) the preparation of 4-hydroxyl-2-(4-fluoroaniline)-5,6-dimethylpyrimidine; (2) the preparation of 4-chloro-2-(4-fluoroaniline)-5,6-dimethylpyrimidine; (3) the preparation of revaprazan hydrochloride. The method has advantages such as simple operations, high product purity, good yield and suitability for industrial production.
    Type: Application
    Filed: November 12, 2015
    Publication date: September 21, 2017
    Inventors: Wenzheng Liu, Guocheng Wang, Qingwei Hou, Qiaoping Cui, Zhanyuan Zhu, Jinping Liu, Mingbo Yang, Hongguang Meng
  • Crystalline forms of temozolomide and the method for preparing same
    Patent number: 9714250
    Abstract: Provided in the present invention are a new method for preparing the crystalline forms of Temozolomide and three types of crystalline form of Temozolomide by the method. Said method comprises the following steps: a Temozolomide is dissolved into dimethyl sulphoxide, a second organic solvent is added for recrystallization to prepare the crystalline forms of Temozolomide, wherein the second organic solvent is an alcohol, a ketone, a halohydrocarbon or an ester.
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: July 25, 2017
    Assignee: Jiangsu Tasly Diyi Pharmaceutical Co., Ltd.
    Inventors: Guocheng Wang, Wenzheng Liu, Yuzhe Gao, Hailong Yang, Qingwei Hou, Yu Zhang
  • The Crystalline Forms of Temozolomide and the Method for Preparing Same
    Publication number: 20160289234
    Abstract: Provided in the present invention are a new method for preparing the crystalline forms of Temozolomide and three types of crystalline form of Temozolomide by the method. Said method comprises the following steps: a Temozolomide is dissolved into dimethyl sulphoxide, a second organic solvent is added for recrystallization to prepare the crystalline forms of Temozolomide, wherein the second organic solvent is an alcohol, a ketone, a halohydrocarbon or an ester.
    Type: Application
    Filed: October 28, 2014
    Publication date: October 6, 2016
    Inventors: Guocheng Wang, Wenzheng LIU, Yuzhe GAO, Hailong YANG, Qingwei HOU, Yu ZHANG