Abstract: A water supply simulation method for interlaced system of river and canal system based on groundwater model, includes: S1. constructing simulated water conveyance channel based on first data, and performing attribute definition on water conveyance channels; S2. acquiring initial seepage, evaporation and discharge; S3. performing reverse water demand calculation; S4. performing sequential water supply simulation; S5. acquiring corresponding water head, obtaining current seepage, evaporation, discharge, head-end water demand and water consumption demand of each water conveyance channel based on water head; S6. judging whether current iteration is converged according to water head, if yes, proceeding to S7, otherwise returning to S3 after update; S7. judging whether there is next time period, if yes, returning to S3 after update, otherwise proceeding to S8; and S8. judging whether there is a next stress period, if yes, returning to S3 after update, otherwise outputting the result obtained in S5, and ending.

Abstract: The invention provides a series of halogenated tetracyclic triterpene derivatives and their preparation and application. It is represented by the following general structural formula: R1 is halogen, R2 is H, and the halogen is selected from fluorine, chlorine, bromine or iodine; or R1 and R2 are each fluorine, and R3 is an amine, alcohol, amino acid, peptide or phosphate linked to oxygen through an acyl group. The derivatives are relatively stable in rat whole blood through pharmacokinetic studies. The absolute bioavailability after a single intragastric administration for male and female rats was 15.6% and 28.4% respectively. The mean bioavailability was 22%. The derivatives showed better in vivo activities compared with the existing standard drugs enalapril and sacubitril valsartan sodium. Meanwhile, hydrophilic prodrugs of the tetracyclic triterpenoid derivatives in the present invention were prepared. The derivatives of the present invention can be used for preparing cardiovascular medicines.

Abstract: A method for estimating quantitative precipitation by combining observation data of a weather radar and rain gauges includes: acquiring original accumulated data of rain gauges and original accumulated precipitation data of a weather radar to obtain rain gauge-weather radar data G/R pairs matched in the same grid; calculating an observation error of the original accumulated precipitation data of the weather radar through the G/R pairs, and detecting abnormal data to generate an initial correction factor field; determining whether a distance correlation exists between the initial correction factor field and the observation error, and if yes, adjusting the initial correction factor field, and correcting the original accumulated precipitation data of the weather radar through the adjusted correction factor field to obtain corrected accumulated precipitation data of the weather radar; and if not, obtaining the corrected accumulated precipitation data of the weather radar directly through a mean field bias (MFB) f

Abstract: A numerical method for simulating a Karez well in association with a groundwater model includes: first, a Karez well section is divided into an underground channel, an open channel and an overflow area, wherein corresponding parameter values are assigned to each part; second, a Karez well conceptual model is established according to the parameters; third, based on the conceptual model, a dynamic relationship between the Karez well and groundwater is simulated using finite difference matrix equations; fourth, a water balance calculation is performed on the converged simulation result (head values); finally, water balance errors, parameter values in the conceptual model and the simulated head value are computed and output for all time periods. This method can simulate the whole process of the Karez well water flow from water collection to water impounding, providing a new approach for analyzing the Karez well seasonal water demand while used in agricultural water management.

Abstract: Disclosed are a tetrahydronaphtho[1,2-b]furan-2(3H)-one derivative of formula (I) and a method of making the same, where definitions of R, R1 and R2 herein are the same as those in the specification. It has been demonstrated by animal experiments that the tetrahydronaphtho[1,2-b]furan-2(3H)-one derivative can significantly inhibit the adjuvant-induced in Wistar male rats so that it can alleviate the primary and secondary lesions, showing a preventive activity to some extent. Therefore, the tetrahydronaphtho[1,2-b]furan-2(3H)-one derivative provided herein is applicable to the preparation of a drug for preventing/treating rheumatoid arthritis, and has promising clinical applications.

Abstract: A water supply simulation method for interlaced system of river and canal system based on groundwater model, includes: S1. constructing simulated water conveyance channel based on first data, and performing attribute definition on water conveyance channels; S2. acquiring initial seepage, evaporation and discharge; S3. performing reverse water demand calculation; S4. performing sequential water supply simulation; S5. acquiring corresponding water head, obtaining current seepage, evaporation, discharge, head-end water demand and water consumption demand of each water conveyance channel based on water head; S6. judging whether current iteration is converged according to water head, if yes, proceeding to S7, otherwise returning to S3 after update; S7. judging whether there is next time period, if yes, returning to S3 after update, otherwise proceeding to S8; and S8. judging whether there is a next stress period, if yes, returning to S3 after update, otherwise outputting the result obtained in S5, and ending.

Abstract: Disclosed are a tetrahydronaphtho[1,2-b]furan-2(3H)-one derivative of formula (I) and a method of making the same, where definitions of R, R1 and R2 herein are the same as those in the specification. It has been demonstrated by animal experiments that the tetrahydronaphtho[1,2-b]furan-2(3H)-one derivative can significantly inhibit the adjuvant-induced in Wistar male rats so that it can alleviate the primary and secondary lesions, showing a preventive activity to some extent. Therefore, the tetrahydronaphtho[1,2-b]furan-2(3H)-one derivative provided herein is applicable to the preparation of a drug for preventing/treating rheumatoid arthritis, and has promising clinical applications.

Abstract: A derivative of inula lineariifolia lactone A, and in particular, a dimethylamine 4-O-acetyl inula lineariifolia lactone A or a salt thereof, preparation of same, and an application of same in preparation of medicine for treating multiple sclerosis.

Abstract: A derivative of inula lineariifolia lactone A, and in particular, a dimethylamine 4-O-acetyl inula lineariifolia lactone A or a salt thereof, preparation of same, and an application of same in preparation of medicine for treating multiple sclerosis.