Abstract: The present application relates an automatically arranged emergency shipwreck position-indicating buoy, which belongs to the technical field of navigation (ship) aids. The automatically arranged emergency shipwreck position-indicating buoy comprises a gasbag, a rope, a high-pressure gas storage device, and a position-indicating light assembly; a rear end of the rope is wound onto a shaft arranged on the gasbag and a front end of the rope is arranged on a ship; a gas outlet of the high-pressure gas storage device is communicated with a gas inlet of the gasbag, and a sealing device is arranged at the gas outlet of the high-pressure gas storage device, and the sealing device is connected to the rope by a connector so as to be arranged on the ship; the position-indicating light assembly is arranged above the gasbag.

Abstract: The present invention discloses a systematic pharmacological method for personalized medicine. In the present invention, biological networks such as gene dependence networks are employed to reflect relationships between genes in pathogenesis. In combination with the gene expression data of a specific patient, a gene rank algorithm, which is capable of utilizing inter-genetic regulation relationships to mine key genes in the pathogenesis of disease in a specific patient, is used to construct a key genes list. Then, personalized medicine is carried out according to whether the drug targets are significantly targeted to the key genes list in the pathogenesis of disease in the specific patient. The systematic pharmacological method for personalized medicine proposed by the present invention is easy to implement, has low cost and high efficiency, and has wide application prospects in precision medicine and drug discovery.

Abstract: The present invention relates to the field of biomedical technology, and discloses a screening method for multi-target drugs and/or drug combinations. It includes the following steps: step (1): searching a drug target database, summarizing a drug target, a target in development and a drug corresponding to each target, obtaining data of a corresponding relationship between the target and the drug; step (2): screening out a related target-target pair according to a systematic genetics method; step (3): screening out a multi-target drug and/or a drug combination according to the data of the corresponding relationship between the target and the drug obtained in step (1) and the related target-target pair obtained in step (2).