Patents by Inventor Qingyun JIANG

Qingyun JIANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BRUTON'S TYROSINE KINASE INHIBITOR AND PREPARATION METHOD THEREFOR
    Publication number: 20230348471
    Abstract: A type of Bruton's tyrosine kinase inhibitor, a preparation method therefor, and an application thereof in the field of medicine. The Bruton's tyrosine kinase inhibitor may be used for preventing and/or treating a disease related to Bruton's tyrosine kinase mediation, such as an autoimmune disease, cancer, or an inflammatory disease. Through experimental research, the provided compound has high selectivity with respect to a Bruton's tyrosine kinase target, and can exhibit a uniquely advantageous medicinal effect in an in vivo animal experiment.
    Type: Application
    Filed: June 18, 2021
    Publication date: November 2, 2023
    Inventors: Xin Xu, Jia Chen, Guan Wang, Linli Zhang, Qingyun Jiang, Chenghao Xi, Kang Sun, Xiaojuan Zhang, Chunqiao Chen, Shuai Li, Qiang Li, Liangze Xia, Ying Wang, Xiaoer Xia
  • Preparation Method for Amide Compound and Application Thereof in Field of Medicine
    Publication number: 20220098178
    Abstract: The present invention relates to a preparation method for an amide compound and an application thereof in the field of medicine. Specifically, provided by the present invention is an amide small molecule compound which is an inhibitor of Zeste gene enhancer homolog 2 (EZH2) and which may be used to prevent and/or treat EZH2-mediated related diseases, comprising tumors, myeloproliferative diseases or autoimmune diseases.
    Type: Application
    Filed: March 24, 2020
    Publication date: March 31, 2022
    Inventors: Xin XU, Jia CHEN, Zhen ZHANG, Liming ZHANG, Qimei WU, Qingyun JIANG, Fengying GUO, Yuyun ZHANG, Hao YU, Ying WANG, Kang SUN, Chengxu ZANG, Chenggang QIN, Xiaobo ZHOU, Xiaojuan ZHANG, Yijin WANG, Xiaoer XIA, Yunfei LI, Jian GE
  • Preparation Method for Amide Compounds and Use Thereof in Medical Field
    Publication number: 20220024941
    Abstract: Provided are a preparation method for amide compounds and use thereof in medical field. Specifically, provided are small molecule amide compounds. Such compounds are inhibitors of enhancer homolog 2 (EZH2) of Zeste gene, and can be used for preventing and/or treating related diseases mediated by EZH2, including tumors, myeloproliferative diseases or autoimmune diseases.
    Type: Application
    Filed: March 24, 2020
    Publication date: January 27, 2022
    Inventors: Xin XU, Jia CHEN, Zhen ZHANG, Liming ZHANG, Qimei WU, Qingyun JIANG, Fengying GUO, Yuyun ZHANG, Hao YU, Xiaojuan ZHANG, Kang SUN, Xiaobo ZHOU, Chengxu ZANG, Yijin WANG, Xiaoer XIA, Yunfei LI, Jian GE
  • ?-opioid receptor agonist and preparation method therefor and use thereof in field of medicine
    Patent number: 11072601
    Abstract: Disclosed are a class of ?-opioid receptor agonists and a preparation method therefor and the use thereof in the field of medicine, belonging to the field of medicinal chemistry. The ?-opioid receptor agonists significantly increase the selectivity for a G protein signaling pathway, and not only can exhibit excellent pharmacodynamic effects, but also significantly improve safety.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: July 27, 2021
    Assignees: SHANGHAI SYNERGY PHARMACEUTICAL SCIENCES CO., LTD., ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD.
    Inventors: Xin Xu, Zhen Zhang, Yunfei Li, Liming Zhang, Fengying Guo, Qingyun Jiang, Dongsheng Li, Linli Zhang, Jinqian Song, Lei Liu, Qiang Liu, Jing Su, Yijin Wang, Jian Ge
  • Pyrido five-element aromatic ring compound, preparation method therefor and use thereof
    Patent number: 10968215
    Abstract: The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: April 6, 2021
    Assignees: SHANGHAI HAIHE PHARMACEUTICAL CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Xuxing Chen, Meiyu Geng, Lei Jiang, Yi Chen, Jianhua Cao, Qingyun Jiang, Qianqian Shen, Jian Ding, Yucai Yao, Zhao Zhao, Yuanfang Xiong
  • ยต-OPIOID RECEPTOR AGONIST AND PREPARATION METHOD THEREFOR AND USE THEREOF IN FIELD OF MEDICINE
    Publication number: 20200270230
    Abstract: Disclosed are a class of ?-opioid receptor agonists and a preparation method therefor and the use thereof in the field of medicine, belonging to the field of medicinal chemistry. The ?-opioid receptor agonists significantly increase the selectivity for a G protein signaling pathway, and not only can exhibit excellent pharmacodynamic effects, but also significantly improve safety.
    Type: Application
    Filed: September 17, 2018
    Publication date: August 27, 2020
    Inventors: Xin Xu, Zhen Zhang, Yunfei Li, Liming Zhang, Fengying Guo, Qingyun Jiang, Dongsheng Li, Linli Zhang, Jinqian Song, Lei Liu, Qiang Liu, Jing Su, Yijin Wang, Jian Ge
  • PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20190211010
    Abstract: The present invention provides a pyrido five-element aromatic ring compound, and a preparation method therefor and a use thereof. The compound provided in the present invention has an inhibitory effect on wild-type and/or mutant EZH2, and is well positioned to become a novel anti-tumor drug or a drug for the treatment of autoimmune diseases.
    Type: Application
    Filed: September 6, 2017
    Publication date: July 11, 2019
    Inventors: Xuxing CHEN, Meiyu GENG, Lei JIANG, Yi CHEN, Jianhua CAO, Qingyun JIANG, Qianqian SHEN, Jian DING, Yucai YAO, Zhao ZHAO, Yuanfang XIONG