Patents by Inventor Qingzhong Yu

Qingzhong Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10196616
    Abstract: An altered avian NDV that contains the coding sequence of avian interleukin-4 (IL-4), or a portion thereof, in the reverse orientation suppresses in-ovo IL-4 production via RNAi when administered to embryonic birds. An immunogenic composition containing this altered NDV is included in this invention. The altered avian NDV can, optionally contain a polynucleotide encoding a heterologous antigen from a heterologous avian pathogen and can produce said heterologous antigen in-ovo.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: February 5, 2019
    Assignees: The United States of America, as represented by the Secretary of Agriculture, University of Georgia Research Foundation, Inc.
    Inventors: Claudio L. Afonso, Valerie C. Marcano, Nany Stivalis Cardenas Garcia, Qingzhong Yu, Tonya L. Taylor
  • Publication number: 20180230439
    Abstract: An altered avian NDV that contains the coding sequence of avian interleukin-4 (IL-4), or a portion thereof, in the reverse orientation suppresses in-ovo IL-4 production via RNAi when administered to embryonic birds. An immunogenic composition containing this altered NDV is included in this invention. The altered avian NDV can, optionally contain a polynucleotide encoding a heterologous antigen from a heterologous avian pathogen and can produce said heterologous antigen in-ovo.
    Type: Application
    Filed: February 7, 2018
    Publication date: August 16, 2018
    Inventors: Claudio L. Afonso, Valerie C. Marcano, Nany Stivalis Cardenas Garcia, Qingzhong Yu, Tonya L. Taylor
  • Patent number: 9950059
    Abstract: Recombinant chimeric viruses based on NDV LaSota strain and containing either ILTV gB or gD are produced. Administration of the chimeric viruses to chickens induces an immune response in the animal against both NDV and ILTV. Immunogenic compositions, plasmids, kits and methods are described.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: April 24, 2018
    Assignee: The United States of America, as represented by the Secretary of Agriculture.
    Inventors: Qingzhong Yu, Stephen J. Spatz, Laszlo Zsak
  • Publication number: 20170072046
    Abstract: Recombinant chimeric viruses based on NDV LaSota strain and containing either ILTV gB or gD are produced. Administration of the chimeric viruses to chickens induces an immune response in the animal against both NDV and ILTV. Immunogenic compositions, plasmids, kits and methods are described.
    Type: Application
    Filed: February 13, 2015
    Publication date: March 16, 2017
    Inventors: Qingzhong YU, Stephen J. SPATZ, Laszlo ZSAK
  • Publication number: 20160030550
    Abstract: Disclosed are compositions, vectors, kits, and methods for inducing an immune response against avian infectious bronchitis virus (IBV). In particular, the compositions, vectors, kits, and methods may be utilized to immunize poultry against disease associated with IBV infection or to protect poultry from IBV infection altogether.
    Type: Application
    Filed: October 19, 2015
    Publication date: February 4, 2016
    Applicants: AUBURN UNIVERSITY, The United States of America, as Represented by the Secretary of Agriculture
    Inventors: Haroldo Enrique Toro Guzman, Qingzhong Yu
  • Publication number: 20140141043
    Abstract: Disclosed are compositions, vectors, kits, and methods for inducing an immune response against avian infectious bronchitis virus (IBV). In particular, the compositions, vectors, kits, and methods may be utilized to immunize poultry against disease associated with IBV infection or to protect poultry from IBV infection altogether.
    Type: Application
    Filed: March 15, 2013
    Publication date: May 22, 2014
    Applicant: AUBURN UNIVERSITY
    Inventors: Haroldo Enrique Toro Guzman, Qingzhong Yu
  • Publication number: 20090258035
    Abstract: The present invention relates to poultry vaccines for prevention of Newcastle disease.
    Type: Application
    Filed: March 20, 2009
    Publication date: October 15, 2009
    Applicant: The United States of America, as represented by the Secretary of Agriculture
    Inventors: Qingzhong Yu, Carlos Estevez, Daniel J. King, David L. Suarez, Patti J. Miller
  • Patent number: 5789229
    Abstract: Recombinant methods for recovering wildtype or engineered negative stranded, non-segmented RNA virus genomes containing non-coding 3' and 5' regions (e.g. leader or trailer regions) surrounding one, several or all of the genes of the virus or one or more heterologous gene(s) in the form of ribonucleocapsids containing N, P and L proteins, which are capable of replicating and assembling with the remaining structural proteins to bud and form virions, or which are only capable of infecting one cell, or are transcribing particles, are disclosed. Novel vaccines, gene therapy vectors and antiviral compounds based on these viral particles are also disclosed.
    Type: Grant
    Filed: September 29, 1995
    Date of Patent: August 4, 1998
    Assignee: UAB Research Foundation
    Inventors: Gail W. Wertz, Qingzhong Yu, Laurence A. Ball, John N. Barr, Sean P. J. Whelan
  • Patent number: 5716821
    Abstract: Recombinant methods for recovering wildtype or engineered negative stranded, non-segmented RNA virus genomes containing non-coding 3' and 5' regions (e.g. leader or trailer regions) surrounding one, several or all of the genes of the virus or one or more heterologous gene(s) in the form of ribonucleocapsids containing N, P and L proteins, which are capable of replicating and assembling with the remaining structural proteins to bud and form virions, or which are only capable of infecting one cell, or are defective interfering particles, are disclosed. Novel vaccines, gene therapy vectors and antiviral compounds are also disclosed.
    Type: Grant
    Filed: September 30, 1994
    Date of Patent: February 10, 1998
    Assignee: UAB Research Foundation
    Inventors: Gail W. Wertz, Qingzhong Yu