Abstract: The present application relates to a mold for substrate surface functionalization. In the mold, a rubber strip is provided between an upper mold plate and a lower mold plate in a clamping manner, and a fastening structure enables the upper mold plate and the lower mold plate to clamp in opposite directions, such that the rubber strip, the upper mold plate and the lower mold plate form a mold cavity together under the action of a clamping force; and a positioning structure is used for fixing a substrate in the mold cavity, such that a pouring space is formed between at least one side surface of the substrate and the upper mold plate and/or the lower mold plate, the pouring space being used for pouring a modified material for surface functionalization of the substrate. The present invention further relates to a method for substrate surface functionalization.

Abstract: The present invention relates to long-chain dimethylaniline derivative compounds, their preparation methods, self-assembled texture, and uses thereof. Said compounds show ultralong acting anaesthetic effect, and belong to N-diethylaminoacetyl-2,6-dimethylaniline compounds, having a structure according to formula (I). Said compounds may self-assemble into micelle or gel in an aqueous solvent, and exert an in vivo elongated local anesthetic actions. Local anesthesia and/or analgesic activity can last more than 72 hours. The biomaterials can self-assemble into micelles or gels in water and have local anesthetic effect, as well as can further be used as the coating of medicinal bioactive molecules for treatment of pain, itching and the like and/or the drug carriers, together with as pharmaceutical adjuvants for delivery system. Thus, said materials have a favorable perspective.

Abstract: The present invention relates to long-chain dimethylaniline derivative compounds, their preparation methods, self-assembled texture, and uses thereof. Said compounds show ultralong acting anaesthetic effect, and belong to N-diethylaminoacetyl-2,6-dimethylaniline compounds, having a structure according to formula (I). Said compounds may self-assemble into micelle or gel in an aqueous solvent, and exert an in vivo elongated local anesthetic actions. Local anesthesia and/or analgesic activity can last more than 72 hours. The biomaterials can self-assemble into micelles or gels in water and have local anesthetic effect, as well as can further be used as the coating of medicinal bioactive molecules for treatment of pain, itching and the like and/or the drug carriers, together with as pharmaceutical adjuvants for delivery system. Thus, said materials have a favourable perspective.